Results 21 to 30 of about 7,439 (222)
Characterization of cereulide synthetase, a toxin-producing macromolecular machine.
PLoS ONE, 2015 Cereulide synthetase is a two-protein nonribosomal peptide synthetase system that produces a potent emetic toxin in virulent strains of Bacillus cereus.
Diego A Alonzo +2 more
doaj +1 more source
A cyclic carbo-isosteric penta-depsipeptide: cyclo(Phe1–d-Ala2–Gly3–Phe4–APO5)
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound, cyclo(Phe1–d-Ala2–Gly3–Phe4–APO5), C26H32N4O5, is the minor diastereoisomer of a cyclic penta-peptidomimetic analogue containing a novel 2-aminopropyl lactone (APO) motif, which displays the same number of atoms as the native amino ...
Stéphanie M. Guéret, Trixie Wagner
doaj +1 more source
Depsipeptide substrates for sortase-mediated N-terminal protein ligation [PDF]
, 2014 Technologies that allow the efficient chemical modification of proteins under mild conditions are widely sought after. Sortase-mediated peptide ligation provides a strategy for modifying the N or C terminus of proteins. This protocol describes the use of
Michael E Webb +5 more
core +1 more source
Discovery of a Cyclic Depsipeptide from Chaetomium mollipilium by the Genome Mining Approach
, 2022 Genome mining and bioinformatics analyses allowed us to rationally find a candidate biosynthetic gene cluster for a new cyclic depsipeptide of Chaetomium mollipilium.
Taro Ozaki (823047) +11 more
core +1 more source
Evidence for Naturally Produced Beauvericins Containing N-Methyl-Tyrosine in Hypocreales Fungi
Toxins, 2019 Beauvericin is a depsipeptide mycotoxin. The production of several beauvericin analogues has previously been shown among various genera among Hypocreales fungi.
Monika Urbaniak +2 more
doaj +1 more source
Stereocalpin B, a New Cyclic Depsipeptide from the Antarctic Lichen Ramalina terebrata
Metabolites, 2022 Stereocalpin B, a new cyclic depsipeptide (1), and a new dibenzofuran derivative (3), were isolated from the Antarctic lichen, Ramalina terebrata (Ramalinaceae), along with a known cyclic depsipeptide (2).
Seulah Lee +9 more
doaj +1 more source
Marine Drugs, 2013 During our search for new natural products from the marine environment, we discovered a wide range of cyclic peptides from a marine Photobacterium, closely related to P. halotolerans.
Louise Kjaerulff +6 more
doaj +1 more source
Transcriptional Modulation Using HDACi Depsipeptide Promotes Immune Cell-Mediated Tumor Destruction of Murine B16 Melanoma [PDF]
, 2008 With melanoma, as with many other malignancies, aberrant transcriptional repression is a hallmark of refractory cancer. To restore gene expression, use of a histone deacetylase inhibitor (HDACi) is expected to be effective.
Sato, Atsuko +19 more
core +1 more source
A new depsipeptide antibiotic, citropeptin. [PDF]
Agricultural and Biological Chemistry, 1990 An actinomycete identified as Streptomyces flavidovirens was found to produce a new cyclic hexadepsipeptide antibiotic, designated citropeptin. Citropeptin showed antitumor activity against P388 murine leukemia.
HAYAKAWA, Yoichi +3 more
openaire +3 more sources
, 2008 Factors that determine the chirality of supramolecular helical tapes formed by a backbone-modified amylin(20–29) depsipeptide and inverso-depsipeptide, were studied by Fourier transform infrared spectroscopy, circular dichroism and transmission electron ...
Mulder, Gwenn E. +9 more
core +2 more sources