Results 51 to 60 of about 7,439 (222)
Total Synthesis of the Depsipeptide FR‐901375. [PDF]
ChemInform, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Yanping, Chen +4 more
openaire +2 more sources
Pest Management Science, EarlyView.This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King +6 more
wiley +1 more source
, 2016 Coibamide A, a Potent Antiproliferative Cyclic Depsipeptide from the Panamanian Marine Cyanobacterium Leptolyngbya ...
Luz I. Romero (2417095) +8 more
core +1 more source
Three New Depsipeptides, Homiamides A–C, Isolated from Streptomyces sp., ROA-065
MoleculesThree new depsipeptides, homiamides A–C (1–3), were isolated from a marine sediment-derived strain of Streptomyces sp., ROA-065. The planar structures of homiamides A–C (1–3) were elucidated using mass spectrometry (MS) and nuclear magnetic resonance ...
Jeong-Hyeon Kim +8 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley +1 more source
, 2013 (A) H719 cells with deficient DNMT1, DKD of DNMT1/DNMT3A, DKD of DNMT1/DNMT3B, or TKD (triple knockdown) of DNMT1/DNMT3A/DNMT3B were treated with or without depsipeptide at 0.1 µM for 6 hrs, and cell proliferation was tested with the MTT assay.
Donglai Wang (49052) +15 more
core +1 more source
Endophytic Fungi Natural Factories of Novel Bioactive Compounds
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev +18 more
wiley +1 more source
Total Synthesis of the Depsipeptide FR-901375
, 2016 The first total synthesis of FR-901375, a novel bicyclic depsipeptide isolated from the fermentation broth of Pseudomonas chloroaphis No. 2522, has been achieved. The synthetic approach involves 13 reaction steps and is achieved in 12% overall yield. The
Yoshito Abe (663027) +4 more
core +1 more source
Myxobacterial Depsipeptide Chondramides Interrupt SARS-CoV-2 Entry by Targeting Its Broad, Cell Tropic Spike Protein: Antagonistic Prospects for Anti-COVID-19 Drug Discovery [PDF]
, 2021 The severity of the COVID-19 pandemic necessitated the search for drugs against the causative viral agent, SARS-CoV-2. Among the promising targets is the viral surface of SARS-CoV-2 adorned by spike proteins appearing as crown-like structures known for ...
Joe Anthony, Manzano +8 more
core +1 more source
Development of a high-throughput strategy for discovery of potent analogues of antibiotic lysocin E
Nature Communications, 2019 The depsipeptide Lysocin E has antibacterial activity against methicillin-resistant Staphylococcus aureus. Here, the authors developed a high-throughput one-bead-on-compound method for the synthesis and screening lysocin E derivatives, with several hits ...
Hiroaki Itoh +7 more
doaj +1 more source