Results 71 to 80 of about 9,955 (253)
Pathogens, 2020 Fungi from the Hypocreales order synthesize a range of toxic non-ribosomal cyclic peptides with antimicrobial, insecticidal and cytotoxic activities. Entomopathogenic Beauveria, Isaria and Cordyceps as well as phytopathogenic Fusarium spp.
Monika Urbaniak +4 more
doaj +1 more source
The FEBS Journal, EarlyView.Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley +1 more source
The Spore-Surface Depsipeptide of Pithomyces sacchari [PDF]
Journal of General Microbiology, 1967 SUMMARY: The spore-surface spicules of Pithomyces sacchari contain the cyclotetra-depsipeptide, angolide.
P, Riches, A, Rothwell, D W, Russell
openaire +2 more sources
Total Synthesis of the Depsipeptide FR-901375
, 2016 The first total synthesis of FR-901375, a novel bicyclic depsipeptide isolated from the fermentation broth of Pseudomonas chloroaphis No. 2522, has been achieved. The synthetic approach involves 13 reaction steps and is achieved in 12% overall yield. The
Yoshito Abe (663027) +4 more
core +1 more source
Advances in large DNA fragment assembly for microbial cell factory engineering
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Degradable Depsipeptide-Based Multiblock Copolymers with Polyester or Polyetherester Segments
, 2011 Polydepsipeptides, alternating copolymers of an α-amino acid and a α-hydroxy acid, are an interesting group of degradable polymers. They have gained attention as potential degradable implant materials.
Marc Behl +3 more
core +1 more source
Vacuolization as a Novel Approach to Cancer Therapy
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak +9 more
wiley +1 more source
Depsipeptide synthesis by accelerated active ester coupling
, 1968 Protected amino acid active esters react with α-hydroxy acid esters in the presence of several equivalents of imidazole to form aminoaoyl hydroxy acid derivatives in high yield.
FHC Stewart
core +1 more source
The Journal of Pathology, Volume 269, Issue 2, Page 149-163, June 2026.Abstract The conceptualization of mitochondria, previously restricted to their function as cellular ‘powerhouses’, has evolved to recognize their function as central coordinating hubs for the orchestration of cancer cell metabolism, signaling, and fate determination.
Woo Hyun Park
wiley +1 more source
Development of a high-throughput strategy for discovery of potent analogues of antibiotic lysocin E
Nature Communications, 2019 The depsipeptide Lysocin E has antibacterial activity against methicillin-resistant Staphylococcus aureus. Here, the authors developed a high-throughput one-bead-on-compound method for the synthesis and screening lysocin E derivatives, with several hits ...
Hiroaki Itoh +7 more
doaj +1 more source