Results 61 to 70 of about 7,439 (222)

Advances in large DNA fragment assembly for microbial cell factory engineering

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang   +5 more
wiley   +1 more source

Degradable Depsipeptide-Based Multiblock Copolymers with Polyester or Polyetherester Segments

open access: yes, 2011
Polydepsipeptides, alternating copolymers of an α-amino acid and a α-hydroxy acid, are an interesting group of degradable polymers. They have gained attention as potential degradable implant materials.
Marc Behl   +3 more
core   +1 more source

Diastereoselective Assembly of Chiral RuII-Coordinated Depsipeptide-Dendrimers [PDF]

open access: yes, 2013
The synthesis, characterization and chiroptical properties of chiral dendrimers 11–14 formed by ruthenium coordination of2,2′-bipyridine (bpy*) ligands 4, 7, 8 and 10 involving two pairs of enantiomerically pure depsipeptide dendrons bound in 4,4 ...
Buschhaus, Boris, Hirsch, Andreas
core   +1 more source

Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids

open access: yesBeilstein Journal of Organic Chemistry, 2014
The synthesis of six cyclic depsipeptoids inspired by the natural depsipeptide sansalvamide A is described. An efficient and fast synthetic strategy was developed using a combination of consecutive isocyanide-based multicomponent reactions (Ugi and ...
Angélica de Fátima S. Barreto   +3 more
doaj   +1 more source

SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A.

open access: yesPLoS ONE, 2016
In order to expand the repertoire of antifungal compounds a novel, high-throughput phenotypic drug screen targeting fungal phosphatidylserine (PS) synthase (Cho1p) was developed based on antagonism of the toxin papuamide A (Pap-A).
Chelsi D Cassilly   +6 more
doaj   +1 more source

Response Surface Method‐Optimized Microwave‐Assisted Extraction and LC–MS/MS Profiling of Bioactive Compounds Wild Edible Arisaema schimperianum Tuber

open access: yesSEPARATION SCIENCE PLUS, Volume 9, Issue 9, September 2026.
Response surface optimization identified 60% microwave power and 40 s as a balanced condition for recovering bioactive compounds from Arisaema schimperianum tuber. LC–MS/MS profiling revealed diverse metabolites, while freeze‐drying best preserved thermolabile compounds, highlighting an effective strategy for maximizing extraction efficiency and ...
Gezahegn Abawa Zeleke   +2 more
wiley   +1 more source

Depsipeptide synthesis by accelerated active ester coupling

open access: yes, 1968
Protected amino acid active esters react with α-hydroxy acid esters in the presence of several equivalents of imidazole to form aminoaoyl hydroxy acid derivatives in high yield.
FHC Stewart
core   +1 more source

Low dose histone deacetylase inhibitor, depsipeptide (FR901228), promotes adenoviral transduction in human rhabdomyosarcoma cell lines

open access: yes, 2020
Purpose. Transduction of rhabdomyosarcoma (RMS) cells with adenoviral vectors for in vivo and in vitro applications has been limited by the low to absent levels of coxackie and adenovirus receptor (CAR).
Blaine T Mischen   +2 more
core  

Structure and Antibacterial Activity of Ambobactin, a New Telomycin-Like Cyclic Depsipeptide Antibiotic Produced by Streptomyces ambofaciens F3

open access: yesMolecules, 2015
A new telomycin-like cyclic depsipeptide, ambobactin (1), was isolated from the metabolites of Streptomyces ambofaciens F3, an endophyte of Platycladus orientalis.
Shaopeng Wei, Wenhao Zhang, Zhiqin Ji
doaj   +1 more source

depsipeptides

open access: yes, 2014
Citation: 'depsipeptides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01604 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +1 more source

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