Results 61 to 70 of about 5,696 (181)

Thailandepsin A

open access: yesActa Crystallographica Section E, 2011
Thailandepsin A [systematic name: (E)-(1S,5S,6R,9S,20R)-6-[(2S)-butan-2-yl]-5-hydroxy-20-[2-(methylsulfanyl)ethyl]-2-oxa-11,12-dithia-7,19,22-triazabicyclo[7.7.6]docosa-15-ene-3,8,18,21-tetraone], C23H37N3O6S3, is a newly reported [Wang et al. (2011). J.
Cheng Wang, Yi-Qiang Cheng
doaj   +1 more source

Szentiamide, an -formylated Cyclic Depsipeptide from DSM 16338

open access: yesNatural Product Communications, 2011
Szentiamide ( 1 ) a new cyclic hexadepsipeptide was isolated from the culture broth of the entomopathogenic bacterium Xenorhabdus szentirmaii DSM 16338 T .
Birgit Ohlendorf   +3 more
doaj   +1 more source

FK228 from Burkholderia thailandensis MSMB43

open access: yesActa Crystallographica Section E, 2012
FK228 [systematic name: (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone], C24H36N4O6S2, also known as FR901228, depsipeptide, NSC 630176, romidepsin, and ...
Xiang-Yang Liu   +2 more
doaj   +1 more source

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.

open access: yesPLoS Pathogens, 2015
UnlabelledPharmacologically-induced activation of replication competent proviruses from latency in the presence of antiretroviral treatment (ART) has been proposed as a step towards curing HIV-1 infection.
Ole S Søgaard   +18 more
doaj   +1 more source

Preclinical Assessment of a 68Ga-DOTA-Functionalized Depsipeptide as a Radiodiagnostic Infection Imaging Agent

open access: yesMolecules, 2017
The study assessed a radiolabeled depsipeptide conjugate (68Ga-DOTA-TBIA101) for its potential as an imaging agent targeting infection or infection-associated inflammation. 68Ga-labeled DOTA-TBIA101 imaging was performed in (NZR1) healthy rabbits; (NZR2)
Thomas Ebenhan   +5 more
doaj   +1 more source

Kinetik und Mechanismus der selektiven Bindung von Ionen durch Cyclodepsipeptid-Antibiotika

open access: yesCHIMIA, 1972
Stability constants for cation complexes of valinomycin and enniatin B were determined in methanol employing spectrophotometric titrations. Kinetic studies by relaxation methods led to the elucidation of the reaction mechanism of complex formation ...
Th. Funck, F. Eggers, E. Grell
doaj   +1 more source

Clovibactin and Staphylococcus aureus: a new weapon against resistant strains

open access: yesGMS Hygiene and Infection Control
Clovibactin is a new depsipeptide and highly efficacious against () , including methicillin-resistant and vancomycin-resistant , with no apparent resistance. Clovibactutclasses current antibiotics such as vancomycin.
Adeiza, Shuaibu Suleiman
doaj   +1 more source

Konformationsanalyse und Kinetik der Konformationsänderungen von membranaktiven Antibiotika

open access: yesCHIMIA, 1972
Molecular properties of the membrane active antibiotics enniatin B, valinomycin and gramicidin A were investigated in various solvents. The conformational rearrangements of these antibiotics have been studied as a function of solvent polarity by ...
E. Grell, F. Eggers, Th. Funck
doaj   +1 more source

Total Synthesis of Cyclodepsipeptide Xylaroamide A

open access: yesChemistry
Cyclodepsipeptides constitute a structurally diverse class of natural products composed of amino acid and hydroxy acid residues interconnected through both amide and ester bonds.
Rongping Wu   +8 more
doaj   +1 more source

Molecular basis for depsipeptide HDAC inhibitor combinatorial biosynthesis

open access: yesNature Communications
Polyketides and nonribosomal peptides are important natural product classes with wide-ranging medical and agricultural applications. The analogous enzymatic logic employed by bacterial modular polyketide synthases (PKSs) and nonribosomal peptide ...
Munro Passmore   +8 more
doaj   +1 more source

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