Results 1 to 10 of about 11,747 (273)

Probiotic: is diet part of the efficacy equation? [PDF]

open access: yesGut Microbes, 2023
Discovered at the beginning of the 20th century by Nobel laureate Élie Metchnikoff, probiotics have more recently emerged as a potential noninvasive therapeutic approach for the treatment of various chronic diseases.
Héloïse Rytter   +2 more
doaj   +2 more sources

FilaggrinHigh melanomas exhibit active FGFR and allergic signatures with impaired GNA14 and Th1 signatures [PDF]

open access: yesFrontiers in Genetics
Filaggrin gene (FLG/FLG2) product deregulations are associated with various allergic skin diseases, including but not limited to atopic dermatitis, alopecia areata, and ichthyosis vulgaris.
Goodwin G. Jinesh   +2 more
doaj   +2 more sources

Proteome-scale autoantibody profiling in PSC: Associations with clinical phenotypes and evidence for neuroendocrine deregulations [PDF]

open access: yesJHEP Reports
Background & Aims: Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease with heterogeneous phenotypes and progression. Autoimmune traits, such as the presence of autoantibodies, are suspected to drive its heterogeneity.
Martin Cornillet   +27 more
doaj   +2 more sources

Deregulation [PDF]

open access: yesJurist, 2020
Despite the secular increase in regulation, there are important illustrations of its opposite – deregulation. As well as general assaults on needless regulation, or “red tape,” there are many examples of the more focused elimination of legal and regulatory restrictions on entry into certain economic activities.
Cave, Martin   +3 more
  +4 more sources

Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy

open access: yesFrontiers in Immunology, 2022
Chagas disease, caused by the protozoan Trypanosoma cruzi, is an endemic parasitic disease of Latin America, affecting 7 million people. Although most patients are asymptomatic, 30% develop complications, including the often-fatal Chronic Chagasic ...
Pauline Brochet   +62 more
doaj   +1 more source

Deregulations of RNA Pol II Subunits in Cancer

open access: yesApplied Biosciences, 2023
Deregulated transcription is a well-known characteristic of cancer cells, with differentially expressed genes being a common feature of several cancers.
Martina Muste Sadurni, Marco Saponaro
doaj   +1 more source

Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia

open access: yesGut Microbes, 2021
An array of chronic inflammatory diseases, including metabolic diseases such as obesity and diabetes, are thought to be promoted by disturbance of the intestinal microbiota.
Clara Delaroque   +3 more
doaj   +1 more source

Landscape of transcriptional deregulations in the preeclamptic placenta. [PDF]

open access: yesPLoS ONE, 2013
Preeclampsia is a pregnancy disease affecting 5 to 8% of pregnant women and a leading cause of both maternal and fetal mortality and morbidity. Because of a default in the process of implantation, the placenta of preeclamptic women undergoes insufficient
Daniel Vaiman   +2 more
doaj   +1 more source

Reformasi Administrasi di Korea Selatan: Sebuah Pembelajaran Kesuksesan

open access: yesJurnal Wacana Kinerja, 2020
This research examined the strategy and process of administrative reform in South Korea. The method was using a descriptive qualitative approach with analysis of literature study from secondary data.
Ramadhani Haryo Seno
doaj   +1 more source

Metabolic Deregulations in Patients with Polycystic Ovary Syndrome

open access: yesMetabolites, 2023
Polycystic ovary syndrome (PCOS) contributes to endocrine and metabolic complications for women worldwide. The aim of this study was to establish the usefulness of new anthropometric indices and atherogenic indices in the evaluation of metabolic ...
Marzena Jabczyk   +7 more
doaj   +1 more source

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