Results 11 to 20 of about 3,944 (245)

Deal or No Deal? The Effects of Deregulation on Public School Leaders’ Support for Private School Choice in California

open access: yesInternational Journal of Education Policy and Leadership, 2020
Public school leaders might be more likely to support private school voucher programs if they are enacted alongside public school deregulations. We use a survey experiment to examine the effects of public school deregulations on actual public school ...
Corey A. DeAngelis, Lindsey M. Burke
doaj   +1 more source

Deregulation with consensus [PDF]

open access: yesEconomic Theory, 2007
In this paper the authors analyze the problem of eliminating an inefficient regulation that keeps prices artificially high while obtaining consensus from all agents involved. The planner designs an optimal mechanism to maximize a weighted sum of incumbent finins profits and consumer surplus.
Sandro Brusco, Hugo Hopenhayn
openaire   +3 more sources

Landscape of transcriptional deregulations in the preeclamptic placenta. [PDF]

open access: yesPLoS ONE, 2013
Preeclampsia is a pregnancy disease affecting 5 to 8% of pregnant women and a leading cause of both maternal and fetal mortality and morbidity. Because of a default in the process of implantation, the placenta of preeclamptic women undergoes insufficient
Daniel Vaiman   +2 more
doaj   +1 more source

Pathogenic Roles of S100A8 and S100A9 Proteins in Acute Myeloid and Lymphoid Leukemia: Clinical and Therapeutic Impacts

open access: yesMolecules, 2021
Deregulations of the expression of the S100A8 and S100A9 genes and/or proteins, as well as changes in their plasma levels or their levels of secretion in the bone marrow microenvironment, are frequently observed in acute myeloblastic leukemias (AML) and ...
Julie Mondet   +2 more
doaj   +1 more source

Bortezomib and Arsenic Trioxide Activity on a Myelodysplastic Cell Line (P39): A Gene Expression Study

open access: yesTurkish Journal of Hematology, 2015
INTRODUCTION: We aimed to understand the molecular pathways affected by bortezomib and arsenic trioxide treatment on myelomonocytoid cell line P39.
Hakan Savlı   +7 more
doaj   +3 more sources

Early postnatal soluble FGFR3 therapy prevents the atypical development of obesity in achondroplasia. [PDF]

open access: yesPLoS ONE, 2018
Achondroplasia is a rare genetic disease is characterized by abnormal bone development and early obesity. While the bone aspect of the disease has been thoroughly studied, early obesity affecting approximately 50% of them during childhood has been ...
Celine Saint-Laurent   +10 more
doaj   +1 more source

Integrative modelling of the influence of MAPK network on cancer cell fate decision.

open access: yesPLoS Computational Biology, 2013
The Mitogen-Activated Protein Kinase (MAPK) network consists of tightly interconnected signalling pathways involved in diverse cellular processes, such as cell cycle, survival, apoptosis and differentiation.
Luca Grieco   +5 more
doaj   +1 more source

Deregulation and quality [PDF]

open access: yesInternational Journal of Industrial Organization, 1998
Abstract This paper analyses, within a static model, the effect of quality concern on optimal market structure. It focuses on cases where industry quality has public-good like features and is not contractible. It is shown that the introduction of competition raises a free-rider problem which depresses quality (the smaller producer free-rides on its ...
openaire   +3 more sources

Targeting Aberrant Histone Posttranscription Modification Machinery in Esophageal Squamous Cell Carcinoma: Current Findings and Challenges

open access: yesResearch, 2022
Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy, but the survival rates of patients with ESCC have not improved as yet largely because the available targeted therapies are limited.
Gang Ma, Tongyang Gong, Zhihua Liu
doaj   +1 more source

New clinical trial designs in the era of precision medicine

open access: yesMolecular Oncology, 2019
Cancer treatment has made significant strides towards the promise of personalized medicine. Recent scientific advances have shown that there are numerous genetic deregulations that are common in multiple cancer types, raising the possibility of ...
Elena Garralda   +5 more
doaj   +1 more source

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