Results 21 to 30 of about 3,944 (245)

E-Cigarette Liquid Provokes Significant Embryotoxicity and Inhibits Angiogenesis

open access: yesToxics, 2020
E-cigarette smoking (ECS) is a new method of tobacco smoking that is gaining popularity as it is thought to be a “healthy method” of tobacco consumption.
Anas A. Ashour   +7 more
doaj   +1 more source

Predicting Non-Alcoholic Fatty Liver Disease Progression and Immune Deregulations by Specific Gene Expression Patterns

open access: yesFrontiers in Immunology, 2021
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide with rising rates in parallel to obesity, type 2 diabetes, and metabolic syndrome.
Fanhong Zeng   +11 more
doaj   +1 more source

Apoptosis regulation in adrenocortical carcinoma

open access: yesEndocrine Connections, 2019
Apoptosis evading is a hallmark of cancer. Tumor cells are characterized by having an impaired apoptosis signaling, a fact that deregulates the balance between cell death and survival, leading to tumor development, invasion and resistance to treatment ...
Sofia S Pereira   +3 more
doaj   +1 more source

A Tailspin for Taxi Drivers: Platform Labor, Deregulations, and a Migrant Occupation

open access: yesNordic Journal of Working Life Studies, 2021
In this article, we investigate Norwegian taxi drivers’ perceptions and experiences of the introduction of Transportation Network Companies (TNCs) such as Uber. We find that taxi drivers are highly critical, but not over technology or TNCs as such. Their
Helga Hiim Staalhane, Anders Vassenden
doaj  

Metabolomics and in-silico analysis reveal critical energy deregulations in animal models of Parkinson's disease. [PDF]

open access: yesPLoS ONE, 2013
Parkinson's disease (PD) is a multifactorial disease known to result from a variety of factors. Although age is the principal risk factor, other etiological mechanisms have been identified, including gene mutations and exposure to toxins. Deregulation of
Pierre O Poliquin   +4 more
doaj   +1 more source

FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons

open access: yesiScience, 2023
Summary: MicroRNAs (miRNAs) modulate mRNA expression, and their deregulation contributes to various diseases including amyotrophic lateral sclerosis (ALS).
Wan Yun Ho   +19 more
doaj   +1 more source

Reformasi Administrasi di Korea Selatan: Sebuah Pembelajaran Kesuksesan

open access: yesJurnal Wacana Kinerja, 2020
This research examined the strategy and process of administrative reform in South Korea. The method was using a descriptive qualitative approach with analysis of literature study from secondary data.
Ramadhani Haryo Seno
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Molecular interactions between NAFLD and xenobiotic metabolism

open access: yesFrontiers in Genetics, 2013
Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, is a complex multifactorial disease characterised by metabolic deregulations that include accumulation of lipids in the liver, lipotoxicity and insulin ...
Adviti eNaik   +3 more
doaj   +1 more source

Pathophysiology of Myelodysplastic Syndromes

open access: yesHemato, 2021
Ineffective hematopoiesis is the major characteristic of early myelodysplastic syndromes. Its pathophysiology relies on a diversity of mechanisms supported by genetic events that develop in aging hematopoietic stem cells.
Michaela Fontenay   +2 more
doaj   +1 more source

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