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Deregulations of RNA Pol II Subunits in Cancer
Deregulated transcription is a well-known characteristic of cancer cells, with differentially expressed genes being a common feature of several cancers.
Marco Saponaro
exaly +3 more sources
Metabolic Deregulations in Patients with Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) contributes to endocrine and metabolic complications for women worldwide. The aim of this study was to establish the usefulness of new anthropometric indices and atherogenic indices in the evaluation of metabolic ...
Karolina Kulik-Kupka +2 more
exaly +3 more sources
FDI deregulations and employment
We empirically investigate whether employment is affected by foreign direct investment (FDI). Empirical results show that the FDI deregulations promote employment by increasing the job creation rate.
Jiawen Hu, Chaoqun Zhan
exaly +3 more sources
IntroductionCervical cancer causes approximately 350,000 deaths each year. The availability of sensitive and specific diagnostic tests to detect cervical cancer in its early stages is essential to improve survival rates.MethodsIn this study, we compared ...
T. Stverakova +8 more
exaly +3 more sources
MicroRNA Deregulations in Head and Neck Squamous Cell Carcinomas
Objectives: Head and neck/oral cancer, predominantly head and neck squamous cell carcinoma (HNSCC), is the sixth most common cancer in the world. While substantial advances have been made to define the genomic alterations associated with head and neck ...
, Anxun Wang
exaly +3 more sources
Histone acetylation and methylation in rare diseases: from molecular mechanisms to clinical presentations [PDF]
Rare diseases, which collectively affecting millions of people worldwide, present unique diagnostic and therapeutic challenges due to their low prevalence and phenotypic heterogeneity.
Burcu Akman +14 more
doaj +2 more sources
FilaggrinHigh melanomas exhibit active FGFR and allergic signatures with impaired GNA14 and Th1 signatures [PDF]
Filaggrin gene (FLG/FLG2) product deregulations are associated with various allergic skin diseases, including but not limited to atopic dermatitis, alopecia areata, and ichthyosis vulgaris.
Goodwin G. Jinesh +2 more
doaj +2 more sources
Despite the secular increase in regulation, there are important illustrations of its opposite – deregulation. As well as general assaults on needless regulation, or “red tape,” there are many examples of the more focused elimination of legal and regulatory restrictions on entry into certain economic activities.
Cave, Martin +3 more
+4 more sources
Chagas disease, caused by the protozoan Trypanosoma cruzi, is an endemic parasitic disease of Latin America, affecting 7 million people. Although most patients are asymptomatic, 30% develop complications, including the often-fatal Chronic Chagasic ...
Pauline Brochet +62 more
doaj +1 more source
Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia
An array of chronic inflammatory diseases, including metabolic diseases such as obesity and diabetes, are thought to be promoted by disturbance of the intestinal microbiota.
Clara Delaroque +3 more
doaj +1 more source

