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Deregulations of RNA Pol II Subunits in Cancer

open access: yesApplied Biosciences, 2023
Deregulated transcription is a well-known characteristic of cancer cells, with differentially expressed genes being a common feature of several cancers.
Marco Saponaro
exaly   +3 more sources

Metabolic Deregulations in Patients with Polycystic Ovary Syndrome

open access: yesMetabolites, 2023
Polycystic ovary syndrome (PCOS) contributes to endocrine and metabolic complications for women worldwide. The aim of this study was to establish the usefulness of new anthropometric indices and atherogenic indices in the evaluation of metabolic ...
Karolina Kulik-Kupka   +2 more
exaly   +3 more sources

FDI deregulations and employment

open access: yesChina Economic Quarterly International
We empirically investigate whether employment is affected by foreign direct investment (FDI). Empirical results show that the FDI deregulations promote employment by increasing the job creation rate.
Jiawen Hu, Chaoqun Zhan
exaly   +3 more sources

Selection of endogenous control and identification of significant microRNA deregulations in cervical cancer

open access: yesFrontiers in Oncology, 2023
IntroductionCervical cancer causes approximately 350,000 deaths each year. The availability of sensitive and specific diagnostic tests to detect cervical cancer in its early stages is essential to improve survival rates.MethodsIn this study, we compared ...
T. Stverakova   +8 more
exaly   +3 more sources

MicroRNA Deregulations in Head and Neck Squamous Cell Carcinomas

open access: yesJournal of Oral & Maxillofacial Research, 2013
Objectives: Head and neck/oral cancer, predominantly head and neck squamous cell carcinoma (HNSCC), is the sixth most common cancer in the world. While substantial advances have been made to define the genomic alterations associated with head and neck ...
, Anxun Wang
exaly   +3 more sources

Histone acetylation and methylation in rare diseases: from molecular mechanisms to clinical presentations [PDF]

open access: yesFrontiers in Cell and Developmental Biology
Rare diseases, which collectively affecting millions of people worldwide, present unique diagnostic and therapeutic challenges due to their low prevalence and phenotypic heterogeneity.
Burcu Akman   +14 more
doaj   +2 more sources

FilaggrinHigh melanomas exhibit active FGFR and allergic signatures with impaired GNA14 and Th1 signatures [PDF]

open access: yesFrontiers in Genetics
Filaggrin gene (FLG/FLG2) product deregulations are associated with various allergic skin diseases, including but not limited to atopic dermatitis, alopecia areata, and ichthyosis vulgaris.
Goodwin G. Jinesh   +2 more
doaj   +2 more sources

Deregulation [PDF]

open access: yesJurist, 2020
Despite the secular increase in regulation, there are important illustrations of its opposite – deregulation. As well as general assaults on needless regulation, or “red tape,” there are many examples of the more focused elimination of legal and regulatory restrictions on entry into certain economic activities.
Cave, Martin   +3 more
  +4 more sources

Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy

open access: yesFrontiers in Immunology, 2022
Chagas disease, caused by the protozoan Trypanosoma cruzi, is an endemic parasitic disease of Latin America, affecting 7 million people. Although most patients are asymptomatic, 30% develop complications, including the often-fatal Chronic Chagasic ...
Pauline Brochet   +62 more
doaj   +1 more source

Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia

open access: yesGut Microbes, 2021
An array of chronic inflammatory diseases, including metabolic diseases such as obesity and diabetes, are thought to be promoted by disturbance of the intestinal microbiota.
Clara Delaroque   +3 more
doaj   +1 more source

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