Results 21 to 30 of about 11,747 (273)
Apoptosis regulation in adrenocortical carcinoma
Endocrine Connections, 2019 Apoptosis evading is a hallmark of cancer. Tumor cells are characterized by having an impaired apoptosis signaling, a fact that deregulates the balance between cell death and survival, leading to tumor development, invasion and resistance to treatment ...
Sofia S Pereira +3 more
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Frontiers in Immunology, 2021 Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide with rising rates in parallel to obesity, type 2 diabetes, and metabolic syndrome.
Fanhong Zeng +11 more
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Global isoform-specific transcript alterations and deregulated networks in clear cell renal cell carcinoma. [PDF]
, 2018 Extensive genome-wide analyses of deregulated gene expression have now been performed for many types of cancer. However, most studies have focused on deregulation at the gene-level, which may overlook the alterations of specific transcripts for a given ...
Girke, Thomas +2 more
core +1 more source
FDI deregulations and employment
China Economic Quarterly InternationalWe empirically investigate whether employment is affected by foreign direct investment (FDI). Empirical results show that the FDI deregulations promote employment by increasing the job creation rate.
Yongbing Chen +3 more
doaj +1 more source
A Tailspin for Taxi Drivers: Platform Labor, Deregulations, and a Migrant Occupation
Nordic Journal of Working Life Studies, 2021 In this article, we investigate Norwegian taxi drivers’ perceptions and experiences of the introduction of Transportation Network Companies (TNCs) such as Uber. We find that taxi drivers are highly critical, but not over technology or TNCs as such. Their
Helga Hiim Staalhane, Anders Vassenden
doaj
Metabolomics and in-silico analysis reveal critical energy deregulations in animal models of Parkinson's disease. [PDF]
PLoS ONE, 2013 Parkinson's disease (PD) is a multifactorial disease known to result from a variety of factors. Although age is the principal risk factor, other etiological mechanisms have been identified, including gene mutations and exposure to toxins. Deregulation of
Pierre O Poliquin +4 more
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MicroRNA Deregulations in Head and Neck Squamous Cell Carcinomas
eJournal of Oral Maxillofacial Research, 2013 Objectives: Head and neck/oral cancer, predominantly head and neck squamous cell carcinoma (HNSCC), is the sixth most common cancer in the world. While substantial advances have been made to define the genomic alterations associated with head and neck ...
Muzaffar Shah-Khan +6 more
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Pathophysiology of Myelodysplastic Syndromes
Hemato, 2021 Ineffective hematopoiesis is the major characteristic of early myelodysplastic syndromes. Its pathophysiology relies on a diversity of mechanisms supported by genetic events that develop in aging hematopoietic stem cells.
Michaela Fontenay +2 more
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Molecular interactions between NAFLD and xenobiotic metabolism
Frontiers in Genetics, 2013 Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, is a complex multifactorial disease characterised by metabolic deregulations that include accumulation of lipids in the liver, lipotoxicity and insulin ...
Adviti eNaik +3 more
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A model for gene deregulation detection using expression data [PDF]
, 2015 In tumoral cells, gene regulation mechanisms are severely altered, and these modifications in the regulations may be characteristic of different subtypes of cancer. However, these alterations do not necessarily induce differential expressions between the
Birmelé, Etienne +5 more
core +5 more sources