Results 31 to 40 of about 67,632 (263)

LncRNA ST6GALNAC3 inhibits dermal fibroblast proliferation and migration in cashmere goat hair follicles via the chi-miR-24-3p/ID4 axis [PDF]

Animal Bioscience
Objective Dermal papilla is developed from the continuous proliferation and differentiation of dermal fibroblasts, which is the key to the normal development of hair follicles.
Rong Ma, Qing Ma, Lu Zhang, Bingjie Ma, Xuxu Bao, Yiming Zhang, Le Wang, Qi Lv, Zhiying Wang, Ruijun Wang, Rui Su, Yanhong Zhao, Fangzheng Shang, Yu Wang, Yanjun Zhang   +14 more
doaj   +1 more source

Interleukin-1β attenuates myofibroblast formation and extracellular matrix production in dermal and lung fibroblasts exposed to transforming growth factor-β1. [PDF]

PLoS ONE, 2014
One of the most potent pro-fibrotic cytokines is transforming growth factor (TGFβ). TGFβ is involved in the activation of fibroblasts into myofibroblasts, resulting in the hallmark of fibrosis: the pathological accumulation of collagen.
Masum M Mia, Miriam Boersema, Ruud A Bank   +2 more
doaj   +1 more source

Contraction-Dependent Apoptosis of Normal Dermal Fibroblasts [PDF]

Journal of Investigative Dermatology, 2001
The mechanisms underlying the contraction-dependent apoptosis of primary fibroblasts are of prime importance in understanding anchorage-dependent survival/apoptosis of dermal fibroblasts. As integrins are essential extracellular matrix receptors in fibroblasts, their role in anchorage-dependent apoptosis/survival of fibroblasts was analyzed.
Niland, Stephan, Cremer, Anja, Fluck, Juliane, Krieg, Thomas, Sollberg, Stephan, Eble, Johannes A.   +5 more
openaire   +2 more sources

3D Cell Migration Studies for Chemotaxis on Microfluidic-Based Chips: A Comparison between Cardiac and Dermal Fibroblasts

Bioengineering, 2018
Fibroblast migration to damaged zones in different tissues is crucial to regenerate and recuperate their functional activity. However, fibroblast migration patterns have hardly been studied in disease terms.
Sandra Pérez-Rodríguez, Esther Tomás-González, José Manuel García-Aznar   +2 more
doaj   +1 more source

Regulation of dermal fibroblasts by human neutrophil peptides

Scientific Reports, 2023
AbstractHuman neutrophil peptides (HNPs) can induce cell proliferation and activation so their growth promoting activities may have potential clinical benefit. This study investigated the effects of HNPs on human dermal fibroblasts. Differential gene expression in HNP-treated cells and genes involved in regulating intracellular pathways were explored ...
Nattarika Niwetbowornchai, Thanawat Chaisirirat, Sira Sriswasdi, Supichcha Saithong, Grace Filbertine, Helen L. Wright, Steven W. Edwards, Sita Virakul, Direkrit Chiewchengchol   +8 more
openaire   +3 more sources

Allogeneic human dermal fibroblasts are viable in peripheral blood mononuclear co-culture [PDF]

Universa Medicina, 2014
BACKGROUND Transplanted allogeneic dermal fibroblasts retain stem cell subpopulations, and are easily isolated, expanded and stored using standard techniques. Their potential for regenerative therapy of chronic wounds should be evaluated.
Restu Syamsul Hadi, Indra Kusuma, Yurika Sandra   +2 more
doaj   +2 more sources

The mechano-chemical circuit in fibroblasts and dendritic cells drives basal cell proliferation in psoriasis

Cell Reports
Summary: Psoriasis is an intractable immune-mediated disorder that disrupts the skin barrier. While studies have dissected the mechanism by which immune cells directly regulate epidermal cell proliferation, the involvement of dermal fibroblasts in the ...
Jingwei Jiang, Xinyi Shao, Weiwei Liu, Mengyue Wang, Qiwei Li, Miaomiao Wang, Yang Xiao, Ke Li, Huan Liang, Nian’ou Wang, Xuegang Xu, Yan Wu, Xinghua Gao, Qiaoli Xie, Xiao Xiang, Wanqian Liu, Wang Wu, Li Yang, Zhong-Ze Gu, Jin Chen, Mingxing Lei   +20 more
doaj   +1 more source

Non pharmacological high-intensity ultrasound treatment of human dermal fibroblasts to accelerate wound healing

Scientific Reports, 2021
Inspired by the effectiveness of low-intensity ultrasound on tissue regeneration, we investigated the potential effect of short-term high-intensity ultrasound treatment for acceleration of wound healing in an in vitro wound model and dermal equivalent ...
Jeong Yu Lee, Dae-Jin Min, Wanil Kim, Bum-Ho Bin, Kyuhan Kim, Eun-Gyung Cho   +5 more
doaj   +1 more source

Metformin-stimulated Mannose Transport in Dermal Fibroblasts [PDF]

Journal of Biological Chemistry, 2004
The biguanide drug metformin stimulates AMP-activated protein kinase, a master regulator of cellular energy metabolism, and has antihyperglycemic activity due to attenuation of gluconeogenesis in hepatocytes and 2-fold stimulation of glucose transport by skeletal muscle.
Jie, Shang, Mark A, Lehrman
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source