Results 21 to 30 of about 272,773 (298)

Dermal fibroblast in cutaneous development and healing [PDF]

WIREs Developmental Biology, 2017
The skin is the largest organ of the body and is composed of two layers: the overlying epidermis and the underlying dermis. The dermal fibroblasts originate from distinct locations of the embryo and contain the positional identity and patterning information in the skin.
Venkata, Thulabandu, Demeng, Chen, Radhika P, Atit   +2 more
openaire   +2 more sources

Human dermal fibroblasts in psychiatry research [PDF]

Neuroscience, 2016
In order to decipher the disease etiology, progression and treatment of multifactorial human brain diseases we utilize a host of different experimental models. Recently, patient-derived human dermal fibroblast (HDF) cultures have re-emerged as promising in vitro functional system for examining various cellular, molecular, metabolic and (patho ...
S. Kálmán, K.A. Garbett, Z. Janka, K. Mirnics   +3 more
openaire   +4 more sources

IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics [PDF]

, 2016
Systemic sclerosis is an autoimmune connective tissue disease in which T cells play a prominent role. We and others have previously demonstrated a role for T cell-derived IL-13 in mediating the induction of collagen in dermal fibroblasts and that ...
van Laar, Jacob, Van Laar, Jacob M., O'Reilly, Steven, Fullard, Nicola, Ciechomska, Marzena, Przyborski, Stefan, van Laar, J.M., O’Reilly, S., Fullard, N., Przyborski, S., Ciechomska, M.   +10 more
core   +2 more sources

Involvement of Aquaporin 1 in the Motility and in the Production of Fibrillin 1 and Type I Collagen of Cultured Human Dermal Fibroblasts

Cosmetics, 2022
Aminocarbonyl proteins increase with age in the dermal layer. Gene Chip analysis of mRNA expression in human dermal fibroblasts cultured on collagen gels treated with glyceraldehyde as an aminocarbonyl protein and on untreated collagen gels showed a ...
Kazuhisa Maeda, Shiori Yoshida
doaj   +1 more source

Involvement of Wnt Signaling in Dermal Fibroblasts [PDF]

The American Journal of Pathology, 2010
Pachydermoperiostosis (PDP) is a rare disease characterized by unique phenotypes of the skin and bone, such as thick skin, implying that it may be caused by dysregulation of mesenchymal cells. The aim of this study is to examine the roles of dermal fibroblasts in the pathogenesis of pachydermia in association with Wnt signaling. The numbers of cultured
Kenji, Kabashima, Jun-Ichi, Sakabe, Ryutaro, Yoshiki, Yasuhiko, Tabata, Kimitoshi, Kohno, Yoshiki, Tokura   +5 more
openaire   +2 more sources

Cell Proteomic Footprint [PDF]

, 2008
The authentication of mammalian cell cultures and their subpopulations are of tremendous demand in biotechnology and cell therapy. However, current techniques are either not efficient or can be very complex and expensive.
Elena Balashova, Maxim Dashtiev, Petr Lokhov   +2 more
core   +1 more source

DETERMINATION OF BIOCOMPATIBILITY AND CYTOTOXICITY OF POROUS TITANIUM-BASED MATERIALS IN EXPERIMENT

Наука и инновации в медицине, 2017
Aim - to evaluate the proliferative activity of dermal fibroblast cultures in the presence of composite materials based on titanium silicides in vitro. Materials and methods.
AV V Kolsanov, AN N Nikolaenko, VV V Ivanov, SA A Prikhodko, PV V Platonov   +4 more
doaj   +1 more source

Murine Dermal Fibroblast Isolation by FACS [PDF]

Journal of Visualized Experiments, 2016
Fibroblasts are the principle cell type responsible for secreting extracellular matrix and are a critical component of many organs and tissues. Fibroblast physiology and pathology underlie a spectrum of clinical entities, including fibroses in multiple organs, hypertrophic scarring following burns, loss of cardiac function following ischemia, and the ...
Graham G, Walmsley, Zeshaan N, Maan, Michael S, Hu, David A, Atashroo, Alexander J, Whittam, Dominik, Duscher, Ruth, Tevlin, Owen, Marecic, H Peter, Lorenz, Geoffrey C, Gurtner, Michael T, Longaker   +10 more
openaire   +2 more sources

5α-Reductase Activity in Cultured Human Dermal Papilla Cells from Beard Compared with Reticular Dermal Fibroblasts [PDF]

, 1990
The activity of 5α -reductase was assessed in cultured human beard dermal papilla cells and reticular dermal fibroblasts to elucidate the mechanism of androgen action in promoting the growth of beards in men. The monolayer was incubated with 50nM of [1,2-
Itami, Satoshi, Kurata, Sotaro, Takayasu, Susumu   +2 more
core   +1 more source

CSL controls telomere maintenance and genome stability in human dermal fibroblasts

Nature Communications, 2019
Conversion of dermal fibroblasts into Cancer Associated Fibroblasts (CAFs) can play an important role in keratinocyte tumour development. Here the authors reveal that CSL plays a role in maintenance of telomeres and genomic integrity in both dermal ...
Giulia Bottoni, Atul Katarkar, Beatrice Tassone, Soumitra Ghosh, Andrea Clocchiatti, Sandro Goruppi, Pino Bordignon, Paris Jafari, Fabio Tordini, Thomas Lunardi, Wolfram Hoetzenecker, Victor Neel, Joachim Lingner, G. Paolo Dotto   +13 more
doaj   +1 more source