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Online preconcentration and determination of chondroitin sulfate, dermatan sulfate and hyaluronic acid in biological and cosmetic samples using capillary electrophoresis.

Journal of Separation Science, 2019
Capillary electrophoresis with large-volume sample stacking using an electroosmotic flow pump was developed for the determination of chondroitin sulfate, dermatan sulfate and hyaluronic acid.
Kanokporn Chindaphan   +4 more
semanticscholar   +1 more source

Enzymatic Reconstruction of Dermatan Sulfate

Biochemical and Biophysical Research Communications, 2000
We investigated the enzymatic reconstruction of dermatan sulfate (DS) using the transglycosylation reaction of testicular hyaluronidase. First, in order to insert the IdoA-GalNAc disaccharide unit into chondroitin sulfate chains consisting of GlcA-GalNAc disaccharide units, desulfated DS as a donor and pyridylaminated (PA) chondroitin 6-sulfate (Ch6S ...
K, Takagaki   +4 more
openaire   +2 more sources

Dermatan sulfate and chondroitin 6-sulfate conformations

Biochemical and Biophysical Research Communications, 1973
Abstract X-ray diffraction patterns show that dermatan sulfate in oriented, crystalline films occurs as two or three or eight-fold helices. The two-fold helix has a greater axial rise per disaccharide residue [ h = 9.6 A ] than the corresponding chondroitin 6-sulfate helix [ h = 9.3 A ] .
S, Arnott   +3 more
openaire   +2 more sources

Potential Therapeutic Application of Chondroitin Sulfate/Dermatan Sulfate

Current Drug Discovery Technologies, 2008
Glycosaminoglycans (GAGs) are complex polysaccharides, which play important roles in cell growth, differentiation, morphogenesis, cell migration, and bacterial/viral infections. Major GAGs include heparin (Hep)/heparan sulfate, and chondroitin sulfate (CS)/dermatan sulfate (DS).
Shuhei, Yamada, Kazuyuki, Sugahara
openaire   +2 more sources

Biosynthesis of Chondroitin/Dermatan Sulfate

IUBMB Life, 2002
AbstractChondroitin sulfate and dermatan sulfate are synthesized as galactosaminoglycan polymers containing N ‐acetylgalactosmine alternating with glucuronic acid. The sugar residues are sulfated to varying degrees and positions depending upon the tissue sources and varying conditions of formation.
Jeremiah E, Silbert, Geetha, Sugumaran
exaly   +3 more sources

Immunology of Chondroitin/Dermatan Sulfate

1995
Variable substitutions and locations of the sulfate esters along the backbone of chondroitin/dermatan sulfate chains, combined with their carbohydrate structures, present topographies to immune systems which can be recognized as antigenic. This has led to the development of a number of monoclonal antibodies which recognize distinct epitopes in the ...
V C, Hascall   +3 more
openaire   +2 more sources

Synthesis of disaccharide fragments of dermatan sulfate

Carbohydrate Research, 1989
Condensation of crystalline methyl 2-azido-4,6-O-benzylidene-2-deoxy-beta-D-galactopyranoside with methyl (2,3,4-tri-O-acetyl-alpha-L-idopyranosyl bromide)uronate in dichloromethane, in the presence of silver triflate and molecular sieve, provided 54% of methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(methyl 2,3,4-tri-O-acetyl-alpha-L-idopyranosyluronate)
MARRA, Alberto   +3 more
openaire   +3 more sources

The anticoagulant effect of heparan sulfate and dermatan sulfate

Thrombosis Research, 1976
Abstract The potency of the various glycosaminoglycans (GAGs) as anticoagulants in the activated partial thromboplastin time (APTT) test system has been investigated. Heparin, heparan sulfate (HS) and dermatan sulfate (DS) exhibit anticoagulant effect.
A N, Teien, U, Abildgaard, M, Höök
openaire   +2 more sources

Plasmatic dermatan sulfate and chondroitin sulfate determination in mucopolysaccharidoses

Journal of Pharmaceutical and Biomedical Analysis, 2013
The evaluation of plasmatic galactosaminoglycans, dermatan sulfate (DS) and chondroitin sulfate (CS) can be helpful in the early identification of MPS patients, also considering that primary storage of one type of GAG can lead to secondary accumulation of other lysosomal substrates.
Nicola, Volpi   +8 more
openaire   +2 more sources

Dermatan sulfates of normal and scarred fascia

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2001
We evaluated the composition of dermatan sulfates (DS) derived from 23 samples of normal and 23 samples of scarred fascia lata. We analyzed the molecular weight of intact DS chains and the length of chain regions comprising: (1) clusters of L-iduronate-containing disaccharides ("iduronic sections"); (2) clusters of D-glucuronate-containing ...
E M, Kozma, K, Olczyk, A, Głowacki
openaire   +2 more sources

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