Results 231 to 240 of about 16,428 (265)

Dendritic Cell Migration to Skin-Draining Lymph Nodes Is Controlled by Dermatan Sulfate and Determines Adaptive Immunity Magnitude. [PDF]

Front Immunol, 2018
Nadafi R, Koning JJ, Veninga H, Stachtea XN, Konijn T, Zwiers A, Malmström A, den Haan JMM, Mebius RE, Maccarana M, Reijmers RM.   +10 more
europepmc   +1 more source

Dermatan sulfate epimerase 1 and dermatan 4-O-sulfotransferase 1 form complexes that generate long epimerized 4-O-sulfated blocks. [PDF]

J Biol Chem, 2018
Tykesson E, Hassinen A, Zielinska K, Thelin MA, Frati G, Ellervik U, Westergren-Thorsson G, Malmström A, Kellokumpu S, Maccarana M.   +9 more
europepmc   +1 more source

Polyethylenimine-dermatan sulfate complex, a bioactive biomaterial with unique toxicity to CD146-positive cancer cells. [PDF]

ACS Biomater Sci Eng, 2017
Kim BK, Kim D, Kwak G, Yhee JY, Kwon IC, Kim SH, Yeo Y.   +6 more
europepmc   +1 more source

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Enzymatic Reconstruction of Dermatan Sulfate

Biochemical and Biophysical Research Communications, 2000
We investigated the enzymatic reconstruction of dermatan sulfate (DS) using the transglycosylation reaction of testicular hyaluronidase. First, in order to insert the IdoA-GalNAc disaccharide unit into chondroitin sulfate chains consisting of GlcA-GalNAc disaccharide units, desulfated DS as a donor and pyridylaminated (PA) chondroitin 6-sulfate (Ch6S ...
Mitsuo Majima, Hidekazu Munakata, Keiichi Takagaki, Ikuko Kakizaki, Masahiko Endo   +4 more
openaire   +3 more sources

Biosynthesis of Chondroitin/Dermatan Sulfate

IUBMB Life, 2002
AbstractChondroitin sulfate and dermatan sulfate are synthesized as galactosaminoglycan polymers containing N ‐acetylgalactosmine alternating with glucuronic acid. The sugar residues are sulfated to varying degrees and positions depending upon the tissue sources and varying conditions of formation.
Jeremiah E. Silbert, Geetha Sugumaran
openaire   +3 more sources

The anticoagulant effect of heparan sulfate and dermatan sulfate

Thrombosis Research, 1976
Abstract The potency of the various glycosaminoglycans (GAGs) as anticoagulants in the activated partial thromboplastin time (APTT) test system has been investigated. Heparin, heparan sulfate (HS) and dermatan sulfate (DS) exhibit anticoagulant effect.
Magnus Höök, Arne N. Teien, Ulrich Abildgaard   +2 more
openaire   +3 more sources

Solvolytic depolymerization of chondroitin and dermatan sulfates [PDF]

Carbohydrate Research, 2009
It is essential to establish a library of glycosaminoglycan oligosaccharides from the chondroitin and dermatan sulfates to investigate their biological functions and structure-activity relationships (SARs). There are several approaches to obtain oligosaccharides using chemical and enzymatic degradation procedures; however, purification of each ...
Robert J. Linhardt, Kenji Sato, Noriko Sakamoto, Shinobu Sakai, Toshihiko Toida, Saori Hosoyama   +5 more
openaire   +2 more sources

Dermatan sulfate and chondroitin 6-sulfate conformations

Biochemical and Biophysical Research Communications, 1973
Abstract X-ray diffraction patterns show that dermatan sulfate in oriented, crystalline films occurs as two or three or eight-fold helices. The two-fold helix has a greater axial rise per disaccharide residue [ h = 9.6 A ] than the corresponding chondroitin 6-sulfate helix [ h = 9.3 A ] .
David W.L. Hukins, J.M. Guss, Struther Arnott, Martin B. Mathews   +3 more
openaire   +3 more sources

Synthesis of disaccharide fragments of dermatan sulfate

Carbohydrate Research, 1989
Condensation of crystalline methyl 2-azido-4,6-O-benzylidene-2-deoxy-beta-D-galactopyranoside with methyl (2,3,4-tri-O-acetyl-alpha-L-idopyranosyl bromide)uronate in dichloromethane, in the presence of silver triflate and molecular sieve, provided 54% of methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(methyl 2,3,4-tri-O-acetyl-alpha-L-idopyranosyluronate)
MARRA, Alberto, XIA D, PETITOU M, SINAY P.   +3 more
openaire   +4 more sources