Protective effects of mesenchymal stromal cell-derived secretome on dermonecrosis induced in rabbits by Loxosceles intermedia spider venom [PDF]
Journal of Venomous Animals and Toxins including Tropical DiseasesBackground: Loxoscelism refers to a set of clinical manifestations caused by the bite of spiders from the Loxosceles genus. The classic clinical symptoms are characterized by an intense inflammatory reaction at the bite site followed by local necrosis ...
Gabriela Marques Rodrigues +16 more
doaj +7 more sources
A Male with Acute Dermonecrosis over the Right Flank [PDF]
Indian Dermatology Online JournalVijayasankar Palaniappan +2 more
doaj +5 more sources
Engineered nanoparticles bind elapid snake venom toxins and inhibit venom-induced dermonecrosis. [PDF]
PLoS Neglected Tropical Diseases, 2018 Envenomings by snakebites constitute a serious and challenging global health issue. The mainstay in the therapy of snakebite envenomings is the parenteral administration of animal-derived antivenoms. Significantly, antivenoms are only partially effective
Jeffrey O'Brien +3 more
doaj +7 more sources
Effects of copaiba oil on dermonecrosis induced by Loxosceles intermedia venom [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2019 Background: Accidents caused by spiders of the genus Loxosceles constitute an important public health problem in Brazil. The venom of Loxosceles sp induces dermonecrosis at the bite site and systemic disease in severe cases. Traditional medicine based on
Mara Fernandes Ribeiro +8 more
doaj +5 more sources
Local Dermonecrosis with Generalized Urticaria Probably Due to Loxosceles rufescens Bite [PDF]
Open Access Macedonian Journal of Medical Sciences, 2020 BACKGROUND: The spiders of the Loxosceles genus, commonly denoted as “brown spiders” or “Mediterranean recluse” or “brown recluse,” belong to the spider family Sicariidae, suborder Labidognatha, order Araneida, class Arachnida, and phylum Arthropoda ...
Charitos, Ioannis Alexandros +3 more
core +7 more sources
Staphylococcus aureus alpha toxin suppresses effective innate and adaptive immune responses in a murine dermonecrosis model. [PDF]
PLoS ONE, 2013 An optimal host response against Staphylococcus aureus skin and soft tissue infections (SSTI) is dependent on IL-1β and IL-17 mediated abscess formation.
Christine Tkaczyk +11 more
doaj +5 more sources
Insights into the Mechanisms Involved in Strong Hemorrhage and Dermonecrosis Induced by Atroxlysin-Ia, a PI-Class Snake Venom Metalloproteinase [PDF]
Toxins, 2017 Hemorrhage is the most prominent effect of snake venom metalloproteinases (SVMPs) in human envenomation. The capillary injury is a multifactorial effect caused by hydrolysis of the components of the basement membrane (BM).
Luciana Aparecida Freitas-de-Sousa +4 more
doaj +5 more sources
Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib. [PDF]
Proc Natl Acad Sci U S ASnakebite envenoming is a neglected tropical disease that causes substantial mortality and morbidity globally. The venom of African spitting cobras often causes permanent injury via tissue-destructive dermonecrosis at the bite site, which is ...
Bartlett KE +13 more
europepmc +10 more sources
Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin [PDF]
EBioMedicine, 2018 Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), typified by the pulse-field type USA300, is an emerging endemic pathogen that is spreading rapidly among healthy people.
Heidi Wolfmeier +6 more
doaj +5 more sources
Rare case of dermonecrosis caused by a recluse spider bite in Europe [PDF]
BMJ Case Reports, 2016 Spider poisoning is rare in Europe, with very few reported cases in the literature. Recluse spider (genus Loxosceles) bites may lead to cutaneous and systemic manifestations known as loxoscelism. We report the second known case of spider bite poisoning in Malta caused by Loxosceles rufescens (Mediterranean recluse spider).
Monique Cachia +3 more
openalex +4 more sources