Results 81 to 90 of about 5,859,979 (225)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Liver DNA methylation of FADS2 associates with FADS2 genotypex

Clinical Epigenetics, 2019
Background Non-alcoholic fatty liver disease has been associated with increased mRNA expression of FADS2 in the liver and estimated activity of delta-6 desaturase in serum, encoded by the FADS2 gene.
Paula Walle, Ville Männistö, Vanessa Derenji de Mello, Maija Vaittinen, Alexander Perfilyev, Kati Hanhineva, Charlotte Ling, Jussi Pihlajamäki   +7 more
doaj   +1 more source

Infection mechanisms of Rhizoctonia cerealis in wheat

iMeta, EarlyView.
We discover that R. cerealis (Rc) is a primary pathogen causing sharp eyespot of wheat after 335 distinct isolates were isolated from 1683 SE‐diseased wheat plants across China over 7 years using a single hyphal tip isolation method. We then generated high‐quality reference genomes via de novo sequencing of five representative Rc isolates and ...
Yan Ren, Ti Liu, Heying Zhao, Qirun Qian, Lufei Cui, Zhipeng Sun, Wenkai Yang, Peng Guo, Sisheng Wang, Lingran Zhang, Congwei Sun, Aolin Jia, Ning Zhang, Feng Chen   +13 more
wiley   +1 more source

Desaturase Genes And Their Use (Patent CA 2311472 A1)

, 1999
cDNA encoding C. elegans .DELTA.6 desaturase has been cloned and sequenced, and the .DELTA.6 desaturase amino acid sequence has been determined. The C.
Napier, J. A.
core  

Effect of seafood mediated PCB exposure on desaturase activity and PUFA profile in Faroese septuagenarians

, 2018
Polychlorinated biphenyl (PCB) exposure may affect serum concentrations of polyunsaturated fatty acids (PUFAs) by inhibiting desaturases Δ5 and Δ6 that drive their synthesis from precursor fatty acids.
Bjerve, Kristian S., Weihe, Pal, Grandjean, Philippe, Choi, Anna Lai, Tøttenborg, Sandra Søgaard   +4 more
core   +1 more source

Decoding ferroptosis via integrated multi‐omics analyses in rice blast

iMeta, EarlyView.
The rice‐Magnaporthe oryzae pathosystem is presented as a host‐pathogen ferroptosis model. Multi‐omics insights connect ferroptosis to several cellular processes, such as iron homeostasis, reactive oxygen species (ROS)/redox imbalance, and polyunsaturated fatty acid‐containing phospholipid (PUFA‐PL) peroxidation, under multiple regulators in rice and M.
Zhibin Liang, Qing Shen, Nam Khoa Nguyen, Ruhui Long, Yuming Ma, Qiao Liu, Naweed I. Naqvi, Nam‐Soo Jwa, Yi‐Zhen Deng   +8 more
wiley   +1 more source

Molecular Cloning and Functional Expression of a Δ9- Fatty Acid Desaturase from an Antarctic Pseudomonas sp. A3.

PLoS ONE, 2016
Fatty acid desaturase enzymes play an essential role in the synthesis of unsaturated fatty acids. Pseudomonas sp. A3 was found to produce a large amount of palmitoleic and oleic acids after incubation at low temperatures. Using polymerase Chain Reaction (
Lawal Garba, Mohd Shukuri Mohamad Ali, Siti Nurbaya Oslan, Raja Noor Zaliha Raja Abd Rahman   +3 more
doaj   +1 more source

Markers of endogenous desaturase activity and risk of coronary heart disease in the CAREMA cohort study.

PLoS ONE, 2012
BackgroundIntakes of n-3 polyunsaturated fatty acids (PUFAs), especially EPA (C20:5n-3) and DHA (C22:6n-3), are known to prevent fatal coronary heart disease (CHD).
Yingchang Lu, Anika Vaarhorst, Audrey H H Merry, Martijn E T Dollé, Robert Hovenier, Sandra Imholz, Leo J Schouten, Bastiaan T Heijmans, Michael Müller, P Eline Slagboom, Piet A van den Brandt, Anton P M Gorgels, Jolanda M A Boer, Edith J M Feskens   +13 more
doaj   +1 more source

Effects of feeding rapeseed oil, soybean oil or linseed oil on stearoyl-CoA desturase expression in the mammary gland of dairy cows [PDF]

, 2009
Extensive biohydrogenation of dietary fatty acids (FA) occurs in the rumen of dairy cattle, giving rise to a high proportion of saturated FA in milk fat. Saturated FA may contribute to increased risks of cardiovascular disease and the metabolic syndrome (
Dijkstra, J., van Vuuren, A.M., Vuuren, A.M., van, van Baal, J., Baal, J., van, Hengel, D., van de, Jacobs, A.A.A., van de Hengel, D.   +7 more
core  

Variation of delta(9)-desaturase activity in dairy cattle

, 2008
peer reviewedThe endogenous production of unsaturated fatty acids (FA), particularly some monounsaturated FA (%MONO) and nearly all conjugated linoleic acids, is regulated by the 9-desaturase activity. The aims of this study were to assess the variation
Dehareng, Frédéric, Bertozzi, Carlo, Mayeres, Patrick, Soyeurt, Hélène, Gengler, Nicolas   +4 more
core   +1 more source