Results 101 to 110 of about 158,350 (323)

Deferasirox desensitization [PDF]

open access: yesThe Journal of Allergy and Clinical Immunology: In Practice, 2016
Karen E, Bruner, Kevin M, White
openaire   +2 more sources

Using artificial intelligence thanabots as “thanatobots” to assist anatomy learning and professional development: Ghosts masquerading as opportunity?

open access: yesAnatomical Sciences Education, EarlyView.
Thanabots—AI‐generated digital representations of deceased donors—could enhance anatomy education by linking medical history with anatomy and fostering humanistic engagement. However, their use poses ethical questions and carries psychological risks, including issues around consent, authenticity, and emotional harm.
Jon Cornwall, Sabine Hildebrandt
wiley   +1 more source

Penicillin allergy de‐labelling in the critical care unit: Simulations to design an intravenous drug provocation test that mirrors the plasma profile of an enteral challenge

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The majority of penicillin allergy labels are incorrect and a label of penicillin allergy is associated with worse outcomes and increased use of healthcare services. Penicillin allergy assessment and de‐labelling may be considered in critically ill patients. An oral penicillin challenge is a common component of most penicillin allergy protocols.
Cleodie Swire   +7 more
wiley   +1 more source

TRAF6-mediated ubiquitination of AKT in the nucleus is a critical event underlying the desensitization of G protein-coupled receptors

open access: yesCell Communication and Signaling
Background Desensitization of G protein–coupled receptors (GPCRs) refers to the attenuation of receptor responsiveness by prolonged or intermittent exposure to agonists.
Chengyan Wu   +7 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Two-year follow-up after drug desensitization in mucopolysaccharidosis

open access: yesOrphanet Journal of Rare Diseases
Background Mucopolysaccharidosis (MPS) type 1 S and type 2 are rare lysosomal storage disorders characterized by impaired enzyme production, resulting in glycosaminoglycans accumulation within lysosomes.
Federico Spataro   +8 more
doaj   +1 more source

Disingenuous ‘box‐ticking’: Undergraduate students' attitudes towards university mental health awareness efforts

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Mental health problems are common among UK undergraduate students. In response, many universities have put considerable effort into raising awareness about student mental health problems and avenues of support (e.g., via workshops, posters, email newsletters and social media posts).
Sorcha Finan, Lucy Foulkes
wiley   +1 more source

Effects of anti-HLA donor-specific antibodies and desensitization on engraftment of haploidentical hematopoietic stem cell transplantation

open access: yes陆军军医大学学报
Objective To investigate the effects of anti-HLA donor-specific antibodies (DSA) and desensitization for DSA+patients on engraftment of haploidentical hematopoietic stem cell transplantation (haplo-HSCT). Methods The patients who underwent haplo-HSCT and
MA Yao, ZHANG Yanfang, ZHOU Kang
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

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