Results 121 to 130 of about 91,740 (302)

Stability of carboplatin infusion solutions used in desensitization protocol

open access: yes, 2019
Carboplatin hypersensitivity reactions are one of the major clinical challenges in treating patients with relapse/recurrent ovarian malignancies.
Vázquez-Sánchez, Rocío   +4 more
core   +1 more source

Clinical Experience With Eliglustat in Children With Gaucher Disease Type 1

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Erika R. Vucko   +6 more
wiley   +1 more source

Effect of volume for injection of the 15th to 16th thoracic interspinous space: An ex vivo study

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Impinging (overriding) spinous processes (ISPs) are commonly identified in horses with back pain. Diagnostic analgesia is widely used as the clinical reference standard for confirming association with clinical signs of back pain, but the specificity of dorsal spinous region diagnostic analgesia remains poorly understood.
Virginia Melly   +6 more
wiley   +1 more source

Desensitization of nicotinic ACh receptors: shaping cholinergic signaling

open access: yes, 2005
Nicotinic ACh receptors (nAChRs) can undergo desensitization, a reversible reduction in response during sustained agonist application. Although the mechanism of desensitization remains incompletely understood, recent investigations have elucidated new ...
YAKEL JL   +4 more
core   +1 more source

Operating in perpetual motion? Coping with the dark side of global boundary spanning

open access: yesGlobal Strategy Journal, EarlyView.
Abstract Research Summary This paper explores how individuals experience and cope with the demands of global boundary spanning in multinational enterprises (MNEs). We foreground temporary colocation as a modality through which mobile global boundary spanners repeatedly traverse multiple boundaries, triggering intense demands with adverse consequences ...
Kieran M. Conroy   +2 more
wiley   +1 more source

Cystic fibrosis: desensitization in delayed hypersensitivity reactions to elexacaftor/tezacaftor/ivacaftor

open access: yesFrontiers in Pharmacology
Background: Cystic fibrosis transmembrane conductance regulator modulators are the only available treatment for cystic fibrosis. Although elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) is well-tolerated, rash has been reported as very frequent. In severe
L. Gómez-Ganda   +9 more
doaj   +1 more source

μ‐Opioid receptor desensitization: homologous or heterologous?

open access: yes, 2012
There is considerable controversy over whether μ-opioid receptor (MOPr) desensitization is homologous or heterologous and over the mechanisms underlying such desensitization.
Chris P. Bailey   +17 more
core   +1 more source

Exploring the Value Realization and Management of Healthcare Data Elements in the Context of New Quality Productive Forces

open access: yesHealth Care Science, EarlyView.
With the rapid advancement of information technology, data has become a key driver of social progress, particularly in the medical field. The accumulation and innovative application of medical data have not only reshaped the structure of medical production factors but also provided a strong impetus for the development of new productivity.
Zhixuan Yu   +4 more
wiley   +1 more source

Longitudinal Study on Post‐Traumatic Stress Disorder, Anxiety, and Depression Among Medical Staff in China

open access: yesHealth Care Science, EarlyView.
A six‐month study of 2650 medical staff found post‐traumatic stress disorder and depression bidirectionally predicted each other, and both drove later anxiety. These findings highlight the need for integrated early screening and intervention strategies targeting post‐traumatic stress disorder, anxiety and depression in high‐stress healthcare settings ...
Zongju Chen   +11 more
wiley   +1 more source

Botulinum Toxin for First Bite Syndrome: A Symptom‐Guided “Follow‐The‐Pain” Injection Strategy

open access: yesHead &Neck, EarlyView.
ABSTRACT Background To evaluate botulinum toxin type A (BoNT‐A) for First Bite Syndrome (FBS) and assess a symptom‐guided “Follow‐the‐Pain” (FTP) injection strategy in patients with incomplete response to standard treatment. Methods Consecutive patients with postoperative FBS were treated with ultrasound‐guided intraparotid BoNT‐A injection.
Rosario Marchese‐Ragona   +5 more
wiley   +1 more source

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