Results 101 to 110 of about 67,666 (216)

“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan, Alyssa Kobayashi, Zhina Sadeghi   +2 more
wiley   +1 more source

Molecular and genomic advances in breast cancer: A comprehensive review of predictive and therapeutic innovations

Precision Medical Sciences, EarlyView.
Breast cancer subtypes, estrogen receptor‐positive (ER+), HER2‐enriched, and TNBC, are defined by genomic and epigenetic signatures. Multi‐omics profiling, immunotherapy, liquid biopsy, and AI‐driven radiogenomics enable precision medicine. Tools like Oncotype DX and PAM50 support personalized care.
Samina Malik, Arif Malik, Shahzad Ahmad, Hassan Mohsin, Shazia Iqbal   +4 more
wiley   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Vitamin B12 desensitization and provocation: Ten-year clinical experience. [PDF]

World Allergy Organ J
Dindar Çelik F, Aksu K, Göktürk Ö, Karahan Y, Baştuğ İnan NB, Uslu B, Demir Ş, Çelik E.   +7 more
europepmc   +1 more source

Clinical characteristics of immediate allergic adverse reactions to intravenous amoxicillin‒clavulanic acid in conscious dogs

Veterinary Record, EarlyView.
Abstract Background Amoxicillin‒clavulanic acid (AMC) is one of the most frequently used antibiotics in small animal practice, and reports on adverse reactions are scarce. The aim of this study was to describe the clinical characteristics of immediate allergic adverse reactions to intravenous (IV) AMC in conscious dogs. Methods The medical records of a
Leonel Frutuoso, Anna Threlfall
wiley   +1 more source

Abattoir antemortem inspection protocol: Observation of unloading improves detection of transport welfare compromises in livestock

Veterinary Record, EarlyView.
Abstract Background Ensuring livestock welfare throughout the production chain, including transport, is an ethical and regulatory imperative. However, protocols to assess transport‐related welfare during routine abattoir inspections are not standardised, including antemortem (AM) inspection by an official veterinarian at UK abattoirs.
Sayaka Mochizuki, Declan Arden, Kurt Arden   +2 more
wiley   +1 more source

Management of Rituximab-Associated Hypersensitivity Reactions with Successfully Applied Desensitization Protocols: A Clinical Experience of 46 Infusions in 11 Patients. [PDF]

J Clin Med
Candar Ö, Özkocaman V, Tülümen Öztürk R, Ersal T, Gülderen E, Yalçın C, Çubukçu S, Güllü Koca T, Hunutlu FÇ, Yavuz Ş, Ediger D, Özkalemkaş F.   +11 more
europepmc   +1 more source

Comparison of the effects of rectal examination on heart rate and eye temperature in cattle of different parity

Veterinary Record, EarlyView.
Abstract Background Rectal examination is a routine procedure in bovine reproductive management, but its physiological impact may vary depending on the cow's age and parity. Stress responses during such procedures can negatively affect animal welfare and compliance, especially in inexperienced animals.
Atakan Cortu, Orsan Gungor
wiley   +1 more source

Mapping the multi-domain allosteric network for CKAMP44 modulation of AMPA receptors. [PDF]

J Biol Chem
Bharti P, Visal S, Vinnakota R, Kumar J.
europepmc   +1 more source

Enhanced Early Detection of Allergic Rhinitis: A Prospective Study on a Symptom‐Based Predictive Model

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Allergic rhinitis (AR) and non‐allergic rhinitis (NAR) share overlapping symptoms but differ in pathophysiology and treatment. Current AR diagnosis relies on skin prick testing (SPT) and serum IgE quantification, both of which are complex.
Ke‐Zhang Zhu, Chao He, Si‐Zhe Zhu, Zheng Liu, Ming Zeng   +4 more
wiley   +1 more source