Results 81 to 90 of about 91,740 (302)

receptor desensitization in CHO cells

open access: yes, 2003
International audienceSerotonin 5-HT 4 receptor isoforms dier in their C-terminal tail and yet little is known about their regulation. In this study, we investigated the desensitization of two human 5-HT 4 receptors stably expressed in CHO cells, with a ...
Mialet, Jeanne   +5 more
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

Sublingual desensitization: a new approach to latex allergy problem

open access: yes, 2002
The prevalence of latex allergy has rapidly increased. Clinical manifestations range from contact urticaria-angioedema and rhinoconjunctivitis to more severe bronchial asthma and anaphylactic shock. The only effective therapy is desensitization.
Roncallo, Chiara   +7 more
core  

Hypnosis and the Desensitization Behavior Therapies

open access: yes, 1970
A distinction is made between desensitization techniques carried out in vivo and other modes of desensitization therapy (flooding, implosion, and systematic desensitization) which rely upon mental operations or processes. Research is reviewed and points
Stuart B. Litvak
core   +1 more source

Multi‐Modal Low‐Power Adaptive Braille Recognition System Based on Hf0.3Zr0.7O2 Memristor

open access: yesAdvanced Science, EarlyView.
A multimodal adaptive perception system based on HZO ferroelectric memristor realizes efficient Braille digit recognition via reservoir computing. It delivers high recognition accuracy with ultralow‑energy analog computation, offering a promising hardware solution for environment‑robust neuromorphic assistive devices for visually impaired users ...
Jikang Xu   +9 more
wiley   +1 more source

Successful desensitization of a child with desferrioxamine hypersensitivity

open access: yes, 1997
Desferrioxamine is produced by a type of actinomycetes. It reacts with trivalent iron ions and forms a hydrosoluble complex called ferrioxamine B. This complex is able to remove iron from ferrous protein, but not from hemoglobin. This feature permits its
Pagliari, Gabriella   +4 more
core  

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

open access: yesAdvanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo   +11 more
wiley   +1 more source

Group Desensitization of Test Anxiety [PDF]

open access: yes, 1970
Following an orientation session in which test-anxious students were instructed in the theory and method of desensitization, eighteen ISU under-graduates applied for a desensitization and counseling program for test-taking anxiety. All students committed
McManus, Marianne
core   +1 more source

Targeted Lysosomal Degradation of Extracellular and Membrane Proteins: From Receptor Hijacking to Programmable Endolysosomal Routing

open access: yesAdvanced Science, EarlyView.
Targeted chimeric degraders engage extracellular or membrane proteins and endocytosable cell‐surface receptors, forming ternary complexes that induce receptor‐mediated internalization. Following endocytosis, post‐endocytic sorting—not internalization alone—determines target fate.
Ke Liu   +6 more
wiley   +1 more source

Food allergy in children: results of a standardized protocol for oral desensitization

open access: yes, 1998
Food allergy in children is still an unresolved problem that merits investigation, particularly when the food is fundamental for the child's growth. Reports in the literature that deal with the possibility of a desensitizing treatment are sporadic and ...
Nucera, Eleonora   +4 more
core  

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