Results 121 to 130 of about 139,872 (278)

Optimizing Monetization Strategies for Generative AI Firms: Implications for Search Engagement

Psychology &Marketing, EarlyView.
ABSTRACT As Generative Artificial Intelligence (GenAI) platforms, such as ChatGPT, have transformed digital search querying behavior, mounting operational costs challenge firms to explore alternative monetization strategies beyond traditional subscription models.
Veronica Rosendo‐Rios, Paurav Shukla
wiley   +1 more source

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk, Michel Wyndaele, Ana Charrua, Christopher Fry, Paul Abrams, Gommert A. van Koeveringe, Anthony J. Kanai, Marcus J. Drake   +7 more
wiley   +1 more source

Desensitization in patients with hypersensitivity to platinum and taxane in gynecological cancers

Cancer Medicine
Background Exposure to paclitaxel and carboplatin has the risk of developing hypersensitivity reactions (HSRs), which could necessitate using less effective treatments to avoid anaphylaxis.
Tibor A. Zwimpfer, Kathrin Scherer, Andreas Schötzau, Viola Heinzelmann‐Schwarz, Karin Hartmann, Marcus Vetter, Céline Montavon   +6 more
doaj   +1 more source

Rates and equilibria at the acetylcholine receptor of electrophorus electroplaques. A study of neurally evoked postsynaptic currents and of voltage-jump relaxations [PDF]

, 1977
Kinetic measurements are employed to reconstruct the steady-state activation of acetylcholine [Ach] receptor channels in electrophorus electroplaques. Neurally evoked postsynaptic currents (PSCs) decay exponentially; at 15°C the rate constant, α, equals ...
Lester, Henry A., Sheridan, Robert E.
core   +2 more sources

“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan, Alyssa Kobayashi, Zhina Sadeghi   +2 more
wiley   +1 more source

Chronic Nicotine Selectively Enhances α4β2* Nicotinic Acetylcholine Receptors in the Nigrostriatal Dopamine Pathway [PDF]

, 2009
These electrophysiological experiments, in slices and intact animals, study the effects of in vivo chronic exposure to nicotine on functional α4β2* nAChRs in the nigrostriatal dopaminergic (DA) pathway.
Cai, Haijiang, Lester, Henry A., McIntosh, J. Michael, McKinney, Sheri, Nashmi, Raad, Xiao, Cheng   +5 more
core  

Structural characterization and optimum machining parameters of jute/carbon fibre hybrid reinforced epoxy composite laminates

Polymer International, EarlyView.
Hybrid jute/carbon epoxy laminates have better mechanical performance and less drilling damage by the use of optimized stacking sequence and machining parameters. Abstract Three composite laminate systems were produced using the standard hand lay‐up method: jute‐fibre‐reinforced polymer (JFRP), carbon‐fibre‐reinforced polymer (CFRP) and a hybrid of the
Paulraj Prabhu, Anbalagan Arunkumar, Nadir Ayrilmis, Vellingiri Suresh, Ram Subbiah, Emarose Shankar   +5 more
wiley   +1 more source

Personal History of Violence and Response to Violence: A Quantitative and Free-Response Study Focusing on College-Age Students [PDF]

, 2011
This study examined the relationship between people’s history with violence and how they responded to a graphically violent real-life video. A review of the literature revealed there had been extensive research done about the effects of media and ...
Haswell, Margaret
core   +1 more source

Molecular and genomic advances in breast cancer: A comprehensive review of predictive and therapeutic innovations

Precision Medical Sciences, EarlyView.
Breast cancer subtypes, estrogen receptor‐positive (ER+), HER2‐enriched, and TNBC, are defined by genomic and epigenetic signatures. Multi‐omics profiling, immunotherapy, liquid biopsy, and AI‐driven radiogenomics enable precision medicine. Tools like Oncotype DX and PAM50 support personalized care.
Samina Malik, Arif Malik, Shahzad Ahmad, Hassan Mohsin, Shazia Iqbal   +4 more
wiley   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source