Results 91 to 100 of about 2,154,958 (312)

Co-creativity through play and game design thinking [PDF]

, 2019
This article discusses the application of game design thinking as a learning process for scaffolding co-creativity in Higher Education based on the GameChangers initiative (gamify.org.uk) part-funded by the Higher Education Funding Council of England ...
Arnab, Sylvester, Clarke, Samantha, Morini, Luca   +2 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Implementasi Design Thinking dalam Membangun Inovasi Model Bisnis Perusahaan Percetakan [PDF]

, 2016
Penelitian ini bertujuan untuk membagun Inovasi Model Bisnis berbasis Kanvas Model Bisnis dengan implementasi Design Thinking pada Perusahaan percetakan di Surabaya.
Saputra, T. A. (Tommy)
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

DEEP EMPATHIC DESIGN

Journal of Industrial Design and Engineering Graphics, 2015
Empathic design is often described as a creative process that translates observations - typically of people and their behaviours into design ideas.
FRAQUELLI Roberto
doaj  

Measuring the effectiveness of programmed instructions (PI) to learn design thinking concepts for secondary school students

Design Science
Self-instructional media in education has the potential to address educational challenges such as accessibility, flexible and personalised learning, real-time assessment and resource efficiency.
Apoorv Naresh Bhatt, Amaresh Chakrabarti
doaj   +1 more source

Transforming Teachers’ Instructional Design for Enhancing Critical Thinking in Ugandan Schools

, 2023
Mauro Giacomazzi, Edimond Serwanga, Gillian Atuheire   +2 more
openalex   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Application of the design strategy that is supported by lateral thinking techniques in product design [PDF]

Journal of Architecture, Art & Humanistic Science
Lateral thinking methods have a key role in developing the designer's ability to deal with challenges and life situations in a more creative way. It gives him the power to produce original and unique ideas.
Ahmed Kassab, Sayed Abdou Ahmed Abdou
doaj   +1 more source

Instructional Design and Application based on Process fortified assessment to enhance Students’ Procedural Thinking ability in Software Education in Elementary School

, 2022
Hwakyung Rim, Hyung-Mo Ahn
openalex   +1 more source