Results 11 to 20 of about 94,577 (347)

Designer drugs and sexual dysfunction. [PDF]

Cent European J Urol, 2015
Benyó M.
europepmc   +2 more sources

Designer Receptors Exclusively Activated by Designer Drugs Approach to Treatment of Sleep-disordered Breathing. [PDF]

Am J Respir Crit Care Med, 2021
Fleury Curado T, Pho H, Freire C, Amorim MR, Bonaventura J, Kim LJ, Lee R, Cabassa ME, Streeter SR, Branco LG, Sennes LU, Fishbein K, Spencer RG, Schwartz AR, Brennick MJ, Michaelides M, Fuller DD, Polotsky VY.   +17 more
europepmc   +2 more sources

Resolving Behavioral Output via Chemogenetic Designer Receptors Exclusively Activated by Designer Drugs. [PDF]

J Neurosci, 2016
Burnett CJ, Krashes MJ.
europepmc   +3 more sources

High-Speed Identification of Designer Drugs by Multiple Mass Spectrometry

CHIMIA, 2005
Stephan Kölliker, Michael Oehme
doaj   +3 more sources

Conformational Restriction of Designer Drugs Reveals Subtype-Selective and Biased CB₂ Agonists with Neuroprotective Effects. [PDF]

J Med Chem
Gioé-Gallo C, Ortigueira S, Prieto-Díaz R, Contino M, Azuaje J, Perrone MG, Riganti C, Alberga D, Mangiatordi GF, Andújar-Arias A, García-Rey A, Graziano G, Stefanachi A, Val C, Martínez AL, Rebassa JB, Reza D, Selas A, Francavilla F, Paleo MR, García-Mera X, Loza MI, Navarro G, Brea J, Sotelo E.   +24 more
europepmc   +2 more sources

Occurrence of Takotsubo Cardiomyopathy after Synthetic Cannabinoid Consumption [PDF]

Addiction and Health, 2019
Background: Synthetic cannabinoid use such as “K2” and “Spice” is popular secondary to its inability to be detected in a urine drug screen. It is associated with a wide range of myocardial pathologies including obstructive and non-obstructive coronary ...
Denelle Mohammed
doaj   +1 more source

The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox

Cells, 2022
The chronic character of chemogenetics has been put forward as one of the assets of the technique, particularly in comparison to optogenetics. Yet, the vast majority of chemogenetic studies have focused on acute applications, while repeated, long-term ...
Marie Claes, Lies De Groef, Lieve Moons
doaj   +1 more source

Oneiroid catatonia due to the usage of spice: The case study

European Psychiatry, 2021
Introduction Designer drugs, as a term, first came about in the 1980s. Most of these “designer drugs” have synthetic cannabinoids and other psychoactive formulas difficulty to detect. Objectives A 28 year man was referred to the hospital.
O. Pityk, A. Pushko, N. Striltsiv, O. Lutska, N. Karbovskyi   +4 more
doaj   +1 more source

Targeted Delivery of Chemogenetic Adeno-Associated Viral Vectors to Cortical Sulcus Regions in Macaque Monkeys by Handheld Injections

Bio-Protocol, 2023
Recent advancements in chemogenetic tools, such as designer receptors exclusively activated by designer drugs (DREADDs), allow the simultaneous manipulation of activity over a specific, broad brain region in nonhuman primates.
Kei Oyama, Yuji Nagai, Takafumi Minamimoto   +2 more
doaj   +1 more source

Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. [PDF]

, 2018
To uncover the circuit-level alterations that underlie atypical sensory processing associated with autism, we adopted a symptom-to-circuit approach in the Fmr1-knockout (Fmr1-/-) mouse model of Fragile X syndrome.
A Contractor, A Estes, A Mullard, Aditi Newadkar, Anubhuti Goel, B Zupan, Barbara Todisco, BN Armbruster, BV Atallah, C He, CA Runyan, Carlos Portera-Cailliau, CD Harvey, CE Robertson, CM Niell, Craig A. Erickson, CS Kogan, CS Kogan, CX He, Daniel A. Cantu, Diego de Alba, Ernest Pedapati, F Farzin, G Fata La, Gunvant R. Chaudhari, HA Zariwala, HK Kato, IS Knoth, J Akerboom, J Poort, Janna Guilfoyle, JC Cottam, JJ LeBlanc, JM Pakan, JP Hamm, JT Gonçalves, K Juczewski, K Plaisted, L Pinto, Lauren M. Schmitt, M Dipoppa, M Rifé, MT Arnett, Nazim Kourdougli, PJ Mineault, SB Hofer, SH Lee, SR Hooper, TA Pologruto, The Dutch-Belgian Fragile X Consortium., TW Chen, Y Gonchar, Y Zhang, ZV Guo   +53 more
core   +2 more sources