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Synergy among non-desmoglein antibodies contributes to the immunopathology of desmoglein antibody–negative pemphigus vulgaris [PDF]
Journal of Biological Chemistry, 2019 Pemphigus vulgaris (PV) is a potentially lethal mucocutaneous blistering disease characterized by IgG autoantibodies (AuAbs) binding to epidermal keratinocytes and inducing this devastating disease. Here, we observed that non-desmoglein (Dsg) AuAbs in the sera of patients with Dsg1/3 AuAb-negative acute PV are pathogenic, because IgGs from these ...
Kyle Amber, Sergei Grando
exaly +5 more sources
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British Journal of Dermatology, 1999
Acantholytic blisters in pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are caused by a dissociation of desmosomes mediated by autoantibodies against desmoglein (Dsg) 3 and Dsg 1, respectively. The blistering occurs at the suprabasilar level in PV and at the subcorneal level in PF, which corresponds to the distribution of target antigens in the ...
K, Iwatsuki +6 more
openaire +2 more sources
Acantholytic blisters in pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are caused by a dissociation of desmosomes mediated by autoantibodies against desmoglein (Dsg) 3 and Dsg 1, respectively. The blistering occurs at the suprabasilar level in PV and at the subcorneal level in PF, which corresponds to the distribution of target antigens in the ...
K, Iwatsuki +6 more
openaire +2 more sources
Nihon rinsho. Japanese journal of clinical medicine, 2011
Shigenori, Tamaki +3 more
openaire +3 more sources
Shigenori, Tamaki +3 more
openaire +3 more sources
2010
Introduction: Blistering diseases are heterogenous group of diseases, inherited and acquired, known for their symptom - pemphix of blister - for a long time, but well defined only in the second part of 20th century. Methods: First to use name pemphigus was Hyppokrates, but first to apply it for blistering disease was Francois Boissier in 1731. Results:
Lipozenčić, Jasna, Marinović, Branka
openaire
Introduction: Blistering diseases are heterogenous group of diseases, inherited and acquired, known for their symptom - pemphix of blister - for a long time, but well defined only in the second part of 20th century. Methods: First to use name pemphigus was Hyppokrates, but first to apply it for blistering disease was Francois Boissier in 1731. Results:
Lipozenčić, Jasna, Marinović, Branka
openaire
The Prevalence of Antibodies against Desmoglein 1 in Endemic Pemphigus Foliaceus in Brazil
New England Journal of Medicine, 2000Günter Hans Filho +2 more
exaly
Desmoglein 1 and desmoglein 3 as autoimmune target of herpetiform pemphigus
Journal of Dermatological Science, 1998Ken Ishii +6 more
openaire +1 more source