Results 151 to 160 of about 18,623 (291)
Antibodies against desmoglein 3 (pemphigus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice. [PDF]
Masayuki Amagai+4 more
openalex +1 more source
JEADV Clinical Practice, Volume 4, Issue 2, Page 580-583, June 2025.
Shirley P. Parraga+3 more
wiley +1 more source
Emerging data and innovative technologies are re-shaping our understanding of the scope and specificity of the autoimmune response in Pemphigus vulgaris (PV), a prototypical humorally mediated autoimmune skin blistering disorder.
Animesh A. Sinha, Thomas Sajda
doaj +1 more source
Stat3 regulates desmoglein 3 transcription in epithelial keratinocytes.
Pemphigus vulgaris (PV) is an epithelial blistering disease caused by autoantibodies to the desmosomal cadherin desmoglein 3 (DSG3). Glucocorticoids improve disease within days by increasing DSG3 gene transcription, although the mechanism for this ...
X. Mao+4 more
semanticscholar +1 more source
Several sporadic cases, in which direct and indirect immunofluorescence studies simultaneously detected IgG and IgA autoantibodies to keratinocyte cell surfaces, have been reported mainly under the name of IgG/IgA pemphigus.
Takashi Hashimoto+14 more
doaj +1 more source
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation
Pemphigus is an autoimmune blistering disease targeting the desmosomal proteins desmoglein (Dsg) 1 and Dsg3. Recently, a genetic variant of the Suppression of tumorigenicity 18 (ST18) promoter was reported to cause ST18 up-regulation, associated with ...
Mariya Y. Radeva+9 more
doaj +1 more source
Desmoglein, the target molecule in autoimmunity and infection
To form the human body and maintain the integrity of its complex tissues, individual cells need to hold tightly to each other. The desmosome is the major type of intercellular adhesive junction, and has desmoglein (Dsg), a cadherin type cell-cell adhesion molecule, as a transmembrane component.
openaire +3 more sources
Desmoglein-1–specific T lymphocytes from patients with endemic pemphigus foliaceus (fogo selvagem) [PDF]
Mong-Shang Lin+10 more
openalex +1 more source
Desmoplakin (DSP) and Desmoglein 1 (DSG1) variants result in skin barrier defects leading to erythroderma, palmoplantar keratoderma and variable [AQ4] other features.
Svetlana Vakkilainen+13 more
doaj +1 more source