Results 61 to 70 of about 7,325 (186)

Bullous Wells’ syndrome successfully treated with omalizumab

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Giulia Ciccarese, William Andrew Rosato, Francesco Drago, Alexandre Raphael Meduri, Francesca Ambrogio, Aurora De Marco, Gerardo Cazzato, Caterina Foti   +7 more
wiley   +1 more source

Factors associated with persistent anti-desmoglein positivity after remission in pemphigus vulgaris: a prospective registry-based cohort study

Frontiers in Immunology
IntroductionAnti-desmoglein (Dsg) antibodies are well-established markers correlated with clinical phenotype and disease severity in pemphigus vulgaris (PV).
Yuxi Zhou, Yuxi Zhou, Yiyi Wang, Mi Wang, Xingli Zhou, Limei Luo, Wei Yan, Wei Li   +7 more
doaj   +1 more source

Identification of Desmoglein as a Cadherin and Analysis of Desmoglein Domain Structure

Journal of Investigative Dermatology, 2007
In the 1980s and early 1990s, the ability to clone complementary DNA (cDNA) resulted in great advances in cell biology, including our understanding of cell adhesion. Cloning the cDNA encoding desmosomal molecules, and the determination of their deduced amino-acid sequences, provided novel insights into their structure and function. It had been shown by
openaire   +3 more sources

Strategies for Monitoring Serum Protein Degradation With an Antibody Array‐Based Technology

Journal of Clinical Laboratory Analysis, Volume 40, Issue 5, March 2026.
This study analyzed the stability of 480 proteins in human serum samples collected from 10 healthy donors and incubated at room temperature for 0–48 h. Antibody array profiling revealed significant time‐dependent degradation of 201 proteins. Subsequent physicochemical and functional enrichment analyses demonstrated that the degraded proteins were ...
Yanlin Wang, Min Lang, Wei Huang, Siwei Zhu, Yingqing Mao, Shuhong Luo, Hua Dong, Ruo‐Pan Huang   +7 more
wiley   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source

Long-lasting Localized Pemphigus Vulgaris without Detectable Serum Autoantibodies Against Desmoglein 3 and Desmoglein 1

Indian Journal of Dermatology, 2016
Pemphigus vulgaris (PV) is an autoimmune blistering disease elicited by anti-desmoglein (DsG) 3 antibody. Although skin lesions tend to be distributed over the entire body, in some patients, they are confined to a restricted area. We report two patients who presented with long-lasting localized PV without detectable anti-DsG antibodies after suffering ...
Asuka Yoshifuku, Kazuyasu Fujii, Hisao Kawahira, Hiromi Katsue, Atsunori Baba, Yuko Higashi, Yumi Aoyama, Takuro Kanekura   +7 more
openaire   +3 more sources

miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas

Journal of Extracellular Vesicles, 2020
Exosomes, or small extracellular vesicles (sEVs), serve as intercellular messengers with key roles in normal and pathological processes. Our previous work had demonstrated that Dsg2 expression in squamous cell carcinoma (SCC) cells enhanced both sEV ...
Joseph P. Flemming, Brianna L. Hill, Mohammed W. Haque, Jessica Raad, Claudine S. Bonder, Larry A. Harshyne, Ulrich Rodeck, Adam Luginbuhl, James K. Wahl, Kenneth Y. Tsai, Peter J. Wermuth, Andrew M. Overmiller, Mỹ G. Mahoney   +12 more
doaj   +1 more source

Keratins Regulate p38MAPK-Dependent Desmoglein Binding Properties in Pemphigus

Frontiers in Immunology, 2018
Keratins are crucial for the anchorage of desmosomes. Severe alterations of keratin organization and detachment of filaments from the desmosomal plaque occur in the autoimmune dermatoses pemphigus vulgaris and pemphigus foliaceus (PF), which are mainly ...
Franziska Vielmuth, Elias Walter, Michael Fuchs, Mariya Y. Radeva, Fanny Buechau, Thomas M. Magin, Volker Spindler, Jens Waschke   +7 more
doaj   +1 more source

Dupilumab Treatment in Pemphigus: A Report of Three Cases and Literature Review

JEADV Clinical Practice, Volume 5, Issue 1, Page 254-257, March 2026.
Capsule summary Pemphigus vulgaris and foliaceus are rare autoimmune blistering diseases traditionally treated with corticosteroids, immunosuppressants, intravenous immunoglobulins, and rituximab. A subset of patients remains refractory or has contraindications to these conventional therapies. We present three cases of pemphigus treated with dupilumab.
José Javier Mateos Rico, Marta Gutiérrez Pascual, María Dolores Caro Gutiérrez, Cristina Marcos Rodríguez, Javier de Quadros Malagón, Francisco Javier Vicente Martín   +5 more
wiley   +1 more source

Squamous cell carcinoma of the soft palate associated with autoantibodies to desmoglein 1 and 3

Dermatology Practical & Conceptual, 2013
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Yoshifumi Maumi, Reiko Suzaki, Naoko Ito, Mizuki Sawada, Sumiko Ishizaki, Mariko Fujibayashi, Motohiko Aiba, Hiroyuki Kaneko, Masaru Tanaka   +8 more
doaj   +1 more source