Results 121 to 130 of about 23,741,217 (251)

A nonsense mutation in the desmoglein 1 gene underlies striate keratoderma

Experimental Dermatology, 2003
Abstract:  Striate keratodermas (PPKS) (OMIM 148700) are a rare group of autosomal dominant genodermatoses characterized by palmoplantar keratoderma typified by streaking hyperkeratosis along each finger and extending onto the palm of the hand. We report a four‐generation kindred originating from Iran‐Syria in which three members were affected with ...
Leon Gilead, Jorge Frank, Jorge Frank, Amalia Martinez-Mir, Angela M. Christiano, Abraham Zlotogorski, Ana Kljuic   +6 more
openaire   +4 more sources

Rituximab therapy improves recalcitrant Pemphigus vulgaris [PDF]

, 2015
Pemphigus is a severe life-threatening blistering disease associated with autoantibodies against cell adhesion proteins desmogleins 1 and 3. Patients with severe pemphigus commonly show high rates of relapse after conventional immunosuppressive therapy ...
Balighi, Kamran, Daneshpazhooh, Maryam, Ehsani, Amirhooshang, Gholamali, Fatemeh, Mofidi, Mohammad, Mortazavi, Hossein, Noormohammadpour, Pedram, Sadeghinia, Ali   +7 more
core  

Striatins as plaque molecules of zonulae adhaerentes in simple epithelia, of tessellate junctions in stratified epithelia, of cardiac composite junctions and of various size classes of lateral adherens junctions in cultures of epithelia- and carcinoma-derived cells [PDF]

, 2014
Proteins of the striatin family (striatins 1–4; sizes ranging from 90 to 110 kDa on SDS-polyacrylamide gel electrophoresis) are highly homologous in their amino acid sequences but can differ in their cell-type-specific gene expression patterns and ...
Dörflinger, Yvette, Franke, Werner W., Frey, Norbert, Heid, Hans, Kuhn, Caecilia, Rickelt, Steffen, Rosin-Arbesfeld, Rina, Zimbelmann, Ralf   +7 more
core   +2 more sources

The progestin receptor interactome in the female mouse hypothalamus: Interactions with synaptic proteins are isoform specific and ligand dependent [PDF]

, 2017
Progestins bind to the progestin receptor (PR) isoforms, PR-A and PR-B, in brain to influence development, female reproduction, anxiety, and stress. Hormone-activated PRs associate with multiple proteins to form functional complexes. In the present study,
Acharya, Kalpana D, Denner, Larry, Edwards, Dean P, Harling, Moriah, Huang, Shixia, Im, Dana D, Lichti, Cheryl F, Nettles, Sabin A, Pattanayak, Cassandra, Sellers, Katherine J, Srivastava, Deepak P, Tetel, Marc J, Vardar-Ulu, Didem   +12 more
core   +3 more sources

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, Volume 12, Issue 23, June 20, 2025.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Functional Effects of the TMEM43 Ser358Leu Mutation in the Pathogenesis of Arrhythmogenic Right Ventricular Cardiomyopathy [PDF]

, 2012
Background: The Ser358Leu mutation in TMEM43, encoding an inner nuclear membrane protein, has been implicated in arrhythmogenic right ventricular cardiomyopathy (ARVC). The pathogenetic mechanisms of this mutation are poorly understood.
Ahmad, Ferhaan, McDonough, Barbara Anne, Rajkumar, Revathi, Seidman, Christine Edry, Sembrat, John C   +4 more
core   +5 more sources

Sita‐ and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross‐sectional study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Sören Dräger, Claudia Kauderer, Svenja Meyhöfer, Leonie Dräger, Jens U. Marquardt, Ralf J. Ludwig, Stephan Arndt, Katharina Boch, Katja Bieber   +8 more
wiley   +1 more source

Prolonged Vancomycin‐Induced Linear IgA Disease in a Patient With Renal Failure

JEADV Clinical Practice, Volume 4, Issue 2, Page 535-539, June 2025.
ABSTRACT A 64‐year‐old man with pneumococcal septic shock and subsequent renal failure underwent treatments with antibiotics including intravenous vancomycin (VCM). Blistering skin lesions appeared 10 days after the initiation of VCM. When the patient was transferred to us 5 months later, blisters with erythema were still observed on the abdomen and ...
Kaori Takezawa, Reiko Noborio, Yuki Nomura, Takahiro Kiyohara, Mako Mine, Takashi Hashimoto   +5 more
wiley   +1 more source

Evidence for Dsg3 in regulating Src signaling by competing with it for binding to caveolin-1

Data in Brief, 2016
This data article contains extended, complementary analysis related to the research articles entitled “Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src” (Tsang et al., 2010) [1] and figures related to the review ...
Hong Wan, Kuang Lin, Siu Man Tsang, Jutamas Uttagomol   +3 more
doaj  

c-Src/Cav1-dependent activation of the EGFR by Dsg2. [PDF]

, 2016
The desmosomal cadherin, desmoglein 2 (Dsg2), is deregulated in a variety of human cancers including those of the skin. When ectopically expressed in the epidermis of transgenic mice, Dsg2 activates multiple mitogenic signaling pathways and increases ...
Brennan-Crispi, Donna M., Cooper, Felicia, Deguchi, Takahiro, Mahoney, Mỹ G., McGuinn, Kathleen P., Overmiller, Andrew M., Peltonen, Sirkku, Roberts, Brett J., Wahl, James K.   +8 more
core   +2 more sources