Results 101 to 110 of about 8,293 (200)

Pemphigus Foliaceus Autoantibodies Induce Redistribution Primarily of Extradesmosomal Desmoglein 1 in the Cell Membrane. [PDF]

Front Immunol, 2022
Hiermaier M, Kugelmann D, Radeva MY, Didona D, Ghoreschi K, Farzan S, Hertl M, Waschke J.   +7 more
europepmc   +1 more source

Rilzabrutinib-induced transition from pemphigus vulgaris to pemphigus foliaceous: case report and review of the literature

Dermatology Reports
The discovery of the role of Bruton’s Tyrosine Kinase (BTK) in inflammation and autoimmunity has recently led to the development of BTK inhibitors for the treatment of autoimmune diseases, including pemphigus vulgaris.
Christian Ciolfi, Jacopo Tartaglia, Francesca Pampaloni, Laura Fagotto, Andrea Sechi, Mauro Alaibac   +5 more
doaj  

A comprehensive analysis of mRNA expression profiles of Esophageal Squamous Cell Carcinoma reveals downregulation of Desmoglein 1 and crucial genomic targets. [PDF]

Cancer Biomark, 2023
Alotaibi A, Gadekar VP, Gundla PS, Mandarthi S, Ravi S, Mallya D, Tungekar A, Lavanya BV, Bhagavath AK, Cordero MW, Pitkaniemi J, Seetharam RN, Bepari A, Hebbar P.   +13 more
europepmc   +1 more source

Desmoglein 1 in ovine muzzle skin detected by immunohistochemistryand immunoblotting

, 2005
SUMMARY Desmosomes are epithelial adhesion structures that assure the mechanical cell-cell adhesion, by linking the intermediate filaments of two adjacent cells.
Miragliotta, Vincenzo, Coli, Alessandra, Ricciardi, Maria Paola, Stornelli, Maria Rita, Giannessi, Elisabetta, Donadio, Elena, DONADIO E   +6 more
core  

iRHOM2 in skin disease and oesophageal cancer [PDF]

, 2015
PhDMutations in RHBDF2, the gene encoding inactive rhomboid protein iRHOM2, result in the dominantly inherited condition Tylosis with oesophageal cancer (TOC). TOC causes plamoplantar keratoderma, oral precursor lesions and up to a 95 % life-time risk of
Etheridge, Sarah
core  

The IgG "Lupus-Band" Deposition Pattern of Pemphigus Erythematosus Association With the Desmoglein 1 Ectodomain as Revealed by 3 Cases

, 2012
Background: Pemphigus foliaceus is an autoimmune skin disease characterized by subcorneal blistering and IgG antibodies directed against desmoglein 1. In the skin, these antibodies deposit intraepidermally.
Kramer, Duco, Poot, Angelique M., Jonkman, Marcel F., Oktarina, Dyah A. M., Pas, Hendri H., Kramer, Duco; id_orcid, Diercks, Gilles F. H.; id_orcid, Diercks, Gilles F. H.   +7 more
core   +1 more source

Differential Pathomechanisms of Desmoglein 1 Transmembrane Domain Mutations in Skin Disease. [PDF]

J Invest Dermatol, 2022
Zimmer SE, Takeichi T, Conway DE, Kubo A, Suga Y, Akiyama M, Kowalczyk AP.   +6 more
europepmc   +1 more source

Phenotypic alteration of basal cells in oral lichen planus; switching keratin 19 and desmoglein 1 expression

, 2018
application/pdfIn oral lichen planus, extracellular matrix and basal cells are damaged by T-lymphocytes. As a consequence, changes in expression of collagen fibers within the connective tissue and cytoskeletons of the epithelial tissue can be observed ...
Shimada, Katsumitsu, Hasegawa, Hiromasa, 沈, 溌智, 落合, 隆永, 島田, 勝光, Shen, Fa-Chih, 長谷川, 博雅, Ochiai, Takanaga   +7 more
core   +1 more source

Oral pemphigus vulgaris with one year follow-up and complete remission

Oral Oncology Reports
Pemphigus vulgaris is a chronic autoimmune disorder that usually presents with blister formation which are mucocutaneous in nature that causes excruciating erosions.
Dineshkumar Thayalan, Rajkumar Krishnan, Rameshkumar Annasamy, Priyadharsini Nataraj, N. Indumathi   +4 more
doaj   +1 more source

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

, 2005
Mutations in SPINK5, encoding the serine protease inhibitor LEKTI, cause Netherton syndrome, a severe autosomal recessive genodermatosis. Spink5(-/-) mice faithfully replicate key features of Netherton syndrome, including altered desquamation, impaired ...
Zambruno, G., Maaike Kreft, Kishibe, M., Mari Kishibe, Yann Barrandon, Giovanna Zambruno, Peter Elias, Elias, P., Céline Deraison, Barrandon, Y., Bonnart, C., Ishida-Yamamoto, A., Hovnanian, A., Deraison, C., Akemi Ishida-Yamamoto, Chrystelle Bonnart, Arnoud Sonnenberg, Alain Hovnanian, Sonnenberg, A., Kreft, M., Pascal Descargues, Descargues, P.   +21 more
core   +1 more source