Results 81 to 90 of about 8,293 (200)

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 415-424, June 2026.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri   +2 more
wiley   +1 more source

Organoids: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li   +6 more
wiley   +1 more source

Deciphering the full spectrum of Castleman diseases based on a cohort of 700 patients in a western country

open access: yesBritish Journal of Haematology, Volume 208, Issue 6, Page 2036-2046, June 2026.
The spectrum of Castleman diseases has expanded over the past three decades. The phenotype of the diseases varies not only among the three major types but also according to the patient ancestry. Summary Under the Castleman disease (CD) eponym, three distinct diseases sharing common pathological features have been described over time.
Eric Oksenhendler   +4 more
wiley   +1 more source

Expression of desmoglein-1 and claudin-1 in the ectocervical epithelium.

open access: yes, 2022
Boxplots showing the height (A) and area (B) of the ectocervical epithelium as well as the height of the three individual layers based on desmoglein-1 staining (C), and based on claudin-1 staining (D).
Paulo Czarnewski (5820374)   +16 more
core   +1 more source

Bridging Rare to Common Diseases: Precision Medicine and the Transforming Landscape of Pediatric Allergy and Immunology

open access: yesPediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
This graphical abstract illustrates the conceptual framework linking rare and common diseases in pediatric allergy and immunology through precision medicine. On the left, rare conditions such as inborn errors of immunity and primary atopic disorders represent well‐defined monogenic models that reveal fundamental mechanisms of immune dysregulation.
Riccardo Castagnoli   +26 more
wiley   +1 more source

Serological diagnosis of autoimmune bullous skin diseases: Prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy

open access: yesOrphanet Journal of Rare Diseases, 2012
Background Various antigen-specific immunoassays are available for the serological diagnosis of autoimmune bullous diseases. However, a spectrum of different tissue-based and monovalent antigen-specific assays is required to establish the diagnosis ...
van Beek Nina   +9 more
doaj   +1 more source

Use of Domain-Swapped Molecules for Conformational Epitope Mapping of Desmoglein 3 in Pemphigus Vulgaris

open access: yes, 2000
Pemphigus vulgaris is an autoimmune blistering disease caused by autoantibodies against desmoglein 3, a member of the desmosomal cadherin family. These autoantibodies recognize conformation-dependent epitopes on desmoglein 3.
Nishikawa, Takeji   +5 more
core   +1 more source

Colocalization of desmoglein-2 and integrin-beta8 in N-MVECs.

open access: yes, 2013
A) Immunostaining of N-MVECs with anti-desmoglein-2 and anti-integrin-beta8 antibodies (nuclei stained with DAPI) in a single N-MVEC (upper row) and in a group of N-MVECs (lower row).
Simona Serratì (220041)   +13 more
core   +1 more source

Correlations of the mean fluorescence intensity of desmoglein-1 and claudin-1 versus estradiol levels in the DMPA and control groups.

open access: yes, 2022
Spearman’s correlations of the MFI of (A-B) desmoglein-1 and (C-D) claudin-1 expression as assessed for potential influence of plasma estradiol levels in the control and DMPA groups, respectively. P-values (TIFF)
Paulo Czarnewski (5820374)   +16 more
core   +1 more source

بررسی وجود آنتی‌بادی دسموگلین 1 در بیماران مبتلا به لیشمانیوز جلدی

open access: yesمجله دانشکده پزشکی اصفهان, 2012
مقدمه: پمفیگوس فولیاسه، یکی از بیماریهای پوستی اتوایمیون است که بوسیله حضور آنتی بادیهای آنتیمیگردد. تصور میشود تشکیل این آنتی بادیها، از طریق وکتورهای بیماریهای انگلی مانند لیشمانیازیس که در مناطق آندمیک پمفیگوس فولیاسه شیوع فراوانتری دارند واسطه گری ...
Fariba Jaffary   +4 more
doaj  

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