Results 91 to 100 of about 29,699,951 (159)

The Transition from Pemphigus Foliaceus to Pemphigus Vegetans—An Intriguing Phenomenon within the Spectrum of Autoimmune Blistering Diseases: A Case Report

Dermato
Pemphigus vegetans and pemphigus foliaceus are rare autoimmune blistering diseases characterized by the disruption of desmosomal adhesion proteins, particularly desmoglein 3 and desmoglein 1.
Olguța Anca Orzan, Liliana Gabriela Popa, Iulia Badiu, Ana Ion, Călin Giurcăneanu, Beatrice Bălăceanu-Gurău, Irina Tudose   +6 more
doaj   +1 more source

A comprehensive analysis of mRNA expression profiles of Esophageal Squamous Cell Carcinoma reveals downregulation of Desmoglein 1 and crucial genomic targets. [PDF]

Cancer Biomark, 2023
Alotaibi A, Gadekar VP, Gundla PS, Mandarthi S, Ravi S, Mallya D, Tungekar A, Lavanya BV, Bhagavath AK, Cordero MW, Pitkaniemi J, Seetharam RN, Bepari A, Hebbar P.   +13 more
europepmc   +1 more source

Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination

Nature Communications, 2018
The epidermis is a multi-layered epithelium formed by the differentiation of basal cells and movement into suprabasal layers. Here the authors define a role for the desmosomal cadherin desmoglein-1 in promoting the delamination of basal cells by ...
Oxana Nekrasova, Robert M. Harmon, Joshua A. Broussard, Jennifer L. Koetsier, Lisa M. Godsel, Gillian N. Fitz, Margaret L. Gardel, Kathleen J. Green   +7 more
doaj   +1 more source

Differential Pathomechanisms of Desmoglein 1 Transmembrane Domain Mutations in Skin Disease. [PDF]

J Invest Dermatol, 2022
Zimmer SE, Takeichi T, Conway DE, Kubo A, Suga Y, Akiyama M, Kowalczyk AP.   +6 more
europepmc   +1 more source

Rilzabrutinib-induced transition from pemphigus vulgaris to pemphigus foliaceous: case report and review of the literature

Dermatology Reports
The discovery of the role of Bruton’s Tyrosine Kinase (BTK) in inflammation and autoimmunity has recently led to the development of BTK inhibitors for the treatment of autoimmune diseases, including pemphigus vulgaris.
Christian Ciolfi, Jacopo Tartaglia, Francesca Pampaloni, Laura Fagotto, Andrea Sechi, Mauro Alaibac   +5 more
doaj  

Oral pemphigus vulgaris with one year follow-up and complete remission

Oral Oncology Reports
Pemphigus vulgaris is a chronic autoimmune disorder that usually presents with blister formation which are mucocutaneous in nature that causes excruciating erosions.
Dineshkumar Thayalan, Rajkumar Krishnan, Rameshkumar Annasamy, Priyadharsini Nataraj, N. Indumathi   +4 more
doaj   +1 more source

A case of anti-laminin gamma-1 (p200) pemphigoid with bullous lesions on the lips, hands and feet showing antibodies to desmoglein 1. [PDF]

Skin Health Dis, 2022
Kaneko F, Ozasa M, Togashi A.
europepmc   +1 more source

Evaluation of the Role of Oral Mucosal Direct Immunofluorescence and Salivary Desmoglein 1 and 3 Enzyme-Linked Immunosorbent Assay in Patients With Oral Mucosal Pemphigus. [PDF]

Indian Dermatol Online J, 2022
Asokan S, Rai R, Boppe A, Umamaheswari G.   +3 more
europepmc   +1 more source

Treatment-naïve pemphigus patients showing IgG tissue deposits have serum IgG antibodies against desmoglein 1 detected more often than those against desmoglein 3: a monocentre laboratory experience. [PDF]

Postepy Dermatol Alergol, 2023
Jałowska M, Dmochowski M, Gornowicz-Porowska J, Bowszyc-Dmochowska M.   +3 more
europepmc   +1 more source

Alpha-1 antitrypsin promotes re-epithelialization by regulating inflammation and migration

Frontiers in Immunology
PurposeRegulation of inflammation and re-epithelialization are critical for efficient wound healing. This study explores the role of human α1-antitrypsin (hAAT), an immunomodulatory protein, in modulating inflammation and promoting re-epithelialization ...
Idan Farber, Idan Farber, Muhammad Wated, Ronen Schuster, Lihie Sheffer, Yuval Anav, Navit Ogen-Shtern, Navit Ogen-Shtern, Alexandra Tsitrina, Diya Tacruri, Anna Bunin, Noah Benjamin Nagar, Maayan Hagbi Bal, Tomer Eliyahu, Dor Halpern, Dor Halpern, Boris Knyazer, Samuel Cohen, Sabri El-Saied, Eli C. Lewis, Eldad Silberstein, Erez Tsumi   +21 more
doaj   +1 more source