Results 121 to 130 of about 16,279,763 (246)

Characterization of Desmoglein-3 Epitope Region Peptides as Synthetic Antigens: Analysis of their in vitro T-cell Stimulating Efficacy, Cytotoxicity, Stability and their Conformational Features [PDF]

, 2015
Desmoglein-3 (Dsg3) adhesion protein is the main target of autoantibodies and autoreactive T cells in Pemphigus vulgaris (PV) autoimmune skin disorder.
Ahmed, Ahmed, Amagai, Amagai, Amber, Anhalt, Berkower, Carmicle, Chou, Delva, Dworschak, Enyedi, Estaquier, Ferrante, Green, Gómara, Hashimoto, Hertl, Holly, Hollósi, Jurcevic, Lin, Mahoney, Manning, Meager, Moesta, Mosmann, Partidos, Povey, Rammensee, Riechers, Ruocco, Sathyanarayana, Scharf, Scharf, Schiltz, Shanmugam, Siddiqui, Siligardi, Slater, Stanley, Sz, Szabados, Thomason, Toniolo, Vass, Veldman, Watts, Wheeler, Woody, Woody, Wucherpfennig, Wucherpfennig, Yang   +53 more
core   +1 more source

Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome [PDF]

, 2016
Tumors can develop a blood supply not only by promoting angiogenesis but also by forming vessel-like structures directly from tumor cells, known as vasculogenic mimicry (VM).
Bonder, C., Brown, M., Ebert, B., Ebert, L., Fedele, C., Foster-Smith, E., Johan, M., McArthur, G., Mintoff, C., Ruszkiewicz, A., Shackleton, M., Sheppard, K., Szeto, P., Tan, L., Zhang, Y.   +14 more
core   +1 more source

Oncolytic Immunotherapy: Where Are We Clinically? [PDF]

, 2014
Peer ...
Hemminki, Akseli
core   +2 more sources

Proteomic analysis of skin invasion by blood fluke larvae. [PDF]

, 2008
BackgroundDuring invasion of human skin by schistosome blood fluke larvae (cercariae), a multicellular organism breaches the epidermis, basement membrane, and dermal barriers of skin.
Braschi, Simon, Debnath, Moumita, Hansell, Elizabeth, Ingram, Jessica, Lim, KC, McKerrow, James H, Medzihradszky, Katalin F, Sajid, Mohammed   +7 more
core   +1 more source

Lesions of pemphigus vulgaris on irradiated skin [PDF]

, 2009
Summary Pemphigus vulgaris (PV) is an autoimmune blistering disease produced by IgG autoantibodies against desmoglein (Dsg)3. Lesions on the skin and mucosa can, in rare cases, be induced by radiotherapy.
Aguado, L. (Leyre), España, A. (Agustín), Marquina, M. (Miren), Pretel, M. (Maider), Ruiz-Carrillo, G. (G.)   +4 more
core   +1 more source

2504

Journal of Clinical and Translational Science, 2017
OBJECTIVES/SPECIFIC AIMS: Pemphigus vulgaris (PV) is a potentially fatal blistering disease caused by autoantibodies to the keratinocyte adhesion protein desmoglein 3.
Nina Ran, Christoph Ellebrecht, Eun Jung Choi, Aimee Payne   +3 more
doaj   +1 more source

IgG against the membrane-proximal portion of the desmoglein 3 ectodomain induces loss of keratinocyte adhesion, a hallmark in pemphigus vulgaris.

Journal of Investigative Dermatology, 2022
C. Hudemann, Y. Exner, R. Pollmann, Karina Schneider, A. Zakrzewicz, S. Feldhoff, T. Schmidt, V. Spindler, D. Rafei-Shamsabadi, F. Völlner, J. Waschke, R. Tikkanen, M. Hertl, R. Eming   +13 more
semanticscholar   +1 more source

Epitope definition by proteomic similarity analysis: identification of the linear determinant of the anti-Dsg3 MAb 5H10

Journal of Translational Medicine, 2004
Background Walking along disease-associated protein sequences in the search for specific segments able to induce cellular immune response may direct clinical research towards effective peptide-based vaccines.
Kanduc Darja, Lin Mong-Shang, Mittelman Abraham, Lucchese Alberta, Sinha Animesh A   +4 more
doaj   +1 more source

Antibodies against desmoglein 3 (pemphigus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice. [PDF]

, 1998
Masayuki Amagai, T. Níshikaẃa, Hossein C. Nousari, Grant J. Anhalt, Takashi Hashimoto   +4 more
openalex   +1 more source

Management of Cutaneous Lesions in Brunsting–Perry Pemphigoid (Bpp): A Single‐Center Retrospective Cohort Study

JEADV Clinical Practice, Volume 4, Issue 2, Page 580-583, June 2025.
Shirley P. Parraga, Matthew L. Hrin, Sarah N. Rimmer, Joseph L. Jorizzo   +3 more
wiley   +1 more source