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Pemphigus Vulgaris With an Elevated Faecal Calprotectin Mimicking Inflammatory Bowel Disease: A Case Report. [PDF]
Abdullah A, Bertfield D, Chan C.
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Could vector-derived cadherin mimicry contribute to pemphigus vulgaris? An immunogenetic and <i>in silico</i> study involving HLA-DRB104:02 and 14:01. [PDF]
Toraman B +4 more
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Proton pump inhibitors modulate esophageal epithelial barrier function and crosstalk with eosinophils. [PDF]
Gautam R +6 more
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Abstract Objective The aim of this study was to test the efficacy of autoantibodies to desmoglein 1 and desmoglein 3 detected by ELISA and indirect immunofluorescence in the diagnosis of oral pemphigus and to correlate the antibody titres with the severity of the disease.
Massimo Petruzzi +6 more
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Desmoglein 3 anchors telogen hair in the follicle
Journal of Cell Science, 1998ABSTRACT Little is known about the function of desmosomes in the normal structure and function of hair. Therefore, it was surprising that mice without desmoglein 3 (the autoantigen in pemphigus vulgaris) not only developed mucous membrane and skin lesions like pemphigus patients, but also developed hair loss.
P J, Koch +5 more
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Desmoglein 3 as a prognostic factor in lung cancer
Human Pathology, 2007Desmoglein 3 is a desmosomal protein of the cadherin family. Our cDNA expression profile demonstrated that desmoglein 3 was highly expressed in squamous cell carcinoma of the lung but not detected in pulmonary adenocarcinoma or normal lung. To investigate the clinical significance of desmoglein 3 in lung cancer, we surveyed its expression in primary ...
Junya, Fukuoka +10 more
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Experimental Cell Research, 2008
P120-catenin (p120ctn) is an armadillo-repeat protein that directly binds to the intracytoplasmic domains of classical cadherins. p120ctn binding promotes the stabilization of cadherin complexes on the plasma membrane and thus positively regulates the adhesive activity of cadherins.
Miho, Kanno +6 more
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P120-catenin (p120ctn) is an armadillo-repeat protein that directly binds to the intracytoplasmic domains of classical cadherins. p120ctn binding promotes the stabilization of cadherin complexes on the plasma membrane and thus positively regulates the adhesive activity of cadherins.
Miho, Kanno +6 more
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Oral lichen planus with antibodies to desmogleins 1 and 3
The Journal of Dermatology, 2014AbstractLichen planus (LP) is a chronic inflammatory disorder involving the skin or mucous membranes. Previous studies have demonstrated that some LP patients showed positive enzyme‐linked immunosorbent assay (ELISA) for desmoglein (DSG) antibodies. We report a case with intractable painful oral lesions.
Chihiro, Kinjyo +7 more
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Plakophilin 1 but not plakophilin 3 regulates desmoglein clustering
Cellular and Molecular Life Sciences, 2019Plakophilins (Pkp) are desmosomal plaque proteins crucial for desmosomal adhesion and participate in the regulation of desmosomal turnover and signaling. However, direct evidence that Pkps regulate clustering and molecular binding properties of desmosomal cadherins is missing. Here, keratinocytes lacking either Pkp1 or 3 in comparison to wild type (wt)
Fuchs M +8 more
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