Results 111 to 120 of about 15,816 (206)

Disrupted desmosomes in induced lesions of familial benign chronic pemphigus

, 1979
An occlusive dressing was applied to the unaffected skin of the back of a patient with familial benign chronic pemphigus (FBCP). Small lesions of FBCP appeared after 48 h, and the ultrastructure of successive biopsies was studied. It was concluded that: (
Achten, Georges, De Dobbeleer, Gilbert
core   +1 more source

The desmosome comes into focus

Journal of Cell Biology
The desmosome is a cell–cell adhesive junction that provides integrity and mechanical resistance to tissues through its attachment to the intermediate filament cytoskeleton. Defects in desmosomes cause diseases impacting the heart, epidermis, and other epithelia.
Navaneetha Krishnan Bharathan, Alexa L. Mattheyses, Andrew P. Kowalczyk   +2 more
openaire   +2 more sources

Erratum: SIRT1 activation and its effect on intercalated disc proteins as a way to reduce doxorubicin cardiotoxicity

Frontiers in Pharmacology, 2023
Frontiers Production Office
doaj   +1 more source

Chapter 18 Visualization of Desmosomes in the Electron Microscope

, 2008
Desmosomes are intercellular junctions found in epithelia and some other tissues. Their primary function is strong cell-cell adhesion. They also link the intermediate filament (IF) cytoskeletons between cells and have roles in cell signaling, tissue ...
Anthea Scothern, Scothern, Anthea, Garrod, David, David Garrod   +3 more
core   +1 more source

Dsg2 ectodomain organization increases throughout desmosome assembly

Cell Adhesion & Migration
Desmosomes are intercellular junctions that regulate mechanical integrity in epithelia and cardiac muscle. Dynamic desmosome remodeling is essential for wound healing and development, yet the mechanisms governing junction assembly remain elusive.
William F. Dean, Rose M. Albert, Tomasz J. Nawara, Melanie Ubil, Reena R. Beggs, Alexa L. Mattheyses   +5 more
doaj   +1 more source

Plakoglobin is required for effective intermediate filament anchorage to desmosomes.

, 2008
Desmosomes are adhesive junctions that provide mechanical coupling between cells. Plakoglobin (PG) is a major component of the intracellular plaque that serves to connect transmembrane elements to the cytoskeleton.
Acehan D, Gumper I, Müller EJ, Petzold C, Cowin P, Stokes DL, Sabatini DD   +6 more
core   +1 more source

Analysis of vertebrate desmosomes

, 1983
This thesis is concerned with desmosomes, which are structures responsible for strong intercellular adhesion and are found characteristically between most epithelial cells of vertebrates.
Cowin, Pamela
core   +1 more source

Cadherin regulation of endoplasmic reticulum-plasma membrane contact sites. [PDF]

Cell Rep
Lhamo S, Bharathan NK, Giang W, Levental KR, Simpson CL, Zimmer SE, Saba T, Beaucousin J, Heuzé ML, Kowalczyk AP.   +9 more
europepmc   +1 more source

Regulation of mechanical intercellular junctions and components of the mitochondrial electron transport chain and the TCA cycle in the hypertrophic heart by pyridostigmine or trandolapril. [PDF]

Front Mol Biosci
Drastichova Z, Hejnova L, Boroš A, Behuliak M, Novotny J.   +4 more
europepmc   +1 more source

Desmosome [PDF]

, 2020
openaire   +1 more source