Results 111 to 120 of about 14,857 (218)

Immunomorphologic and Biochemical Identification of the Pemphigus Foliaceous Autoantigen Within Desmosomes

, 1992
Desmosomes are specialized domains of the plasma membrane that play a fundamental role in intercellular adhesion. This adhesive function is mediated at least in part by the cadherin homologous cell adhesion molecule (CAM) desmoglein (dg). Autoantibodies (
Norbert. Roos, John R Stanley, Klemens. Rappersberger, Roos, Norbert., Stanley, John R, Rappersberger, Klemens.   +5 more
core   +1 more source

Erratum: SIRT1 activation and its effect on intercalated disc proteins as a way to reduce doxorubicin cardiotoxicity

Frontiers in Pharmacology, 2023
Frontiers Production Office
doaj   +1 more source

Cadherin Function Is Required for Human Keratinocytes to Assemble Desmosomes and Stratify in Response to Calcium

, 1994
Elevation of the calcium concentration in keratinocyte culture induces the rapid organization of adherens junctions and desmosomes. Formation of these intercellular junctions is accompanied by reorganization of the cytoskeleton and, with a more delayed ...
Wheelock, Margaret J, Lewis, Jani E, Jensen, Pamela J   +2 more
core   +1 more source

Exploring the potential relevance of microRNAs targeting the ARVC-related gene interaction network to cancer: an in silico testing hypothesis

Journal of Biological Research - Thessaloniki
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a genetic disorder of the myocardium. Mutations in the PKP2, DSP, DSG2, DSC2, JUP, TMEM43, PLN and DES genes which encode proteins of the cardiac desmosome have been linked to the disease yet, the
Athanasios Balaskas, Argyris Dallis, Sotirios G Zarogiannis, Chrissi Hatzoglou, Konstantinos I Gourgoulianis, Erasmia Rouka   +5 more
doaj   +1 more source

Biochemical Characterization of the Desmosome [PDF]

Journal of Investigative Dermatology, 2007
Bass-Zubek, Amanda E., Green, Kathleen J.   +1 more
openaire   +3 more sources

Dsg2 ectodomain organization increases throughout desmosome assembly

Cell Adhesion & Migration
Desmosomes are intercellular junctions that regulate mechanical integrity in epithelia and cardiac muscle. Dynamic desmosome remodeling is essential for wound healing and development, yet the mechanisms governing junction assembly remain elusive.
William F. Dean, Rose M. Albert, Tomasz J. Nawara, Melanie Ubil, Reena R. Beggs, Alexa L. Mattheyses   +5 more
doaj   +1 more source

Interkeratinocyte Adherens Juncitons: Immunocytochemical Visualization of Cell-Cell Junctional Structures, Distinct from Desmosomes, in Human Epidermis

, 1996
Vinculin and β-catenin are intracellular attachment proteins linking transmembrane adhesion molecules (E-cadherin) to the actin microfilament cytoskeleton, thus participating in formation of cell-cell adherens junctions, or zonulac adherentes.
Hans W. Kreysel, Daniel Schmitt, Kreysel, Hans W., Kaiser, Hans W., Haftek, Marek, Hansen, Maren U., Marek Haftek, Schmitt, Daniel, Hans W. Kaiser, Maren U. Hansen   +9 more
core   +1 more source

Desmosomes in verrucous carcinoma of the head and neck [PDF]

, 2012
Verrucous carcinoma (VC) is a variant of squamous cell carcinoma (SCC), characterised by its inability to metastasize. In contrast, hybrid carcinomas, composed of VC and foci of conventional SCC, harbour a metastatic potential.
Odar, Katarina, Cardesa, Antonio, Gale, Nina, Stanta, Giorgio, Bonin, Serena, Zidar, Nina   +5 more
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IgG Binds to Desmoglein 3 in Desmosomes and Causes a Desmosomal Split Without Keratin Retraction in a Pemphigus Mouse Model

, 2004
Pemphigus vulgaris (PV) is an autoimmune blistering disease caused by IgG autoantibodies against desmoglein 3 (Dsg3). In this study, we characterized the ultrastructural localization of in vivo-bound IgG, Dsg3, and desmoplakin during the process of ...
Nishikawa, Takeji, Shimizu, Atsushi, Ota, Takayuki, Ishiko, Akira, Atsushi Shimizu, Kazuyuki Tsunoda, Akira Ishiko, Masayuki Amagai, Tsunoda, Kazuyuki, Takeji Nishikawa, Amagai, Masayuki, Takayuki Ota   +11 more
core   +1 more source

Analysis of vertebrate desmosomes

, 1983
This thesis is concerned with desmosomes, which are structures responsible for strong intercellular adhesion and are found characteristically between most epithelial cells of vertebrates.
Cowin, Pamela
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