Results 161 to 170 of about 15,816 (206)

Ephrin-Eph signaling: an important regulator of epithelial integrity and barrier function. [PDF]

Tissue Barriers
Liu M, Charek JG, Vicetti Miguel RD, Cherpes TL.   +3 more
europepmc   +1 more source

Kallikrein related peptidases 7 and 10 and their substrate desmoglein 3 are upregulated in early stage pancreatic cancerous lesions. [PDF]

Sci Rep
Eisenhauer J, Argo R, Martinez AKF, Maldosevic E, Bastea LI, Wehrkamp CJ, Döppler HR, Edenfield BH, Lewis JT, Wallace MB, Storz P.   +10 more
europepmc   +1 more source

Meeting report - Alpine desmosome disease meeting 2024: advances and emerging topics in desmosomes and related diseases.

J Cell Sci
Waschke J, Amagai M, Becker C, Delmar M, Duru F, Garrod DR, Gerull B, Green KJ, Hertl M, Kowalczyk AP, Niessen CM, Nusrat A, Schinner C, Schlegel N, Sivasankar S, Vielmuth F, Spindler V.   +16 more
europepmc   +1 more source

A zebrafish stable model of Galectin-3 to elucidate its role in Arrhythmogenic Cardiomyopathy

Pilichou K, Risato G, Celeghin R, Cason M, Marinas MB, Pinci S, Casas RB, De Gaspari M, Barbera MD, Facchinello N, Rizzo S, Argenton F, Thiene G, Basso C, Tiso N.   +14 more
europepmc   +1 more source

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart. [PDF]

Journal of Cell Biology, 1996
Plakoglobin (gamma-catenin), a member of the armadillo family of proteins, is a constituent of the cytoplasmic plaque of desmosomes as well as of other adhering cell junctions, and is involved in anchorage of cytoskeletal filaments to specific cadherins.
C Birchmeier, Behrend, M., Günthert, U., B Ledermann, F Vogel, M Behrend, Birchmeier, C., V Brinkmann, P Ruiz, U Günthert, Guenthert, U., Franke, W.W., C Thalhammer, Thalhammer, C., Vogel, F., Birchmeier, W., Ruiz, P., Ledermann, B., C Grund, Franke, W. W., Brinkmann, V., Grund, C., W Birchmeier, W W Franke   +23 more
exaly   +2 more sources

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Desmosomal cadherins

Current Opinion in Cell Biology, 2002
New evidence from blocking desmosomal adhesion with anti-adhesion peptides reveals a role for desmosomes in cell positioning in morphogenesis. Desmosomal adhesion is necessary for the stability of adherens junctions in epithelial cell sheets. Knockout and mis-expression of desmosomal cadherins in mice suggests that they may function directly or ...
Garrod, David R., Merritt, Anita J., Nie, Zhuxiang   +2 more
openaire   +3 more sources

ISOLATION OF EPIDERMAL DESMOSOMES [PDF]

Journal of Cell Biology, 1974
A method is reported for the isolation of desmosomes in a high yield and of a purity suitable for biochemical analysis. The procedure utilizes the selective solubilizing action of citric acid-sodium citrate (CASC) buffer, pH 2.6, on the non-cornified layers of cow nose epidermis, followed by discontinuous sucrose density gradient centrifugation ...
A G Matoltsy
exaly   +3 more sources

Desmosomes and hemidesmosomes

Current Opinion in Cell Biology, 1993
Desmosomes and hemidesmosomes are extremely different in their molecular composition. Most of the protein and glycoprotein components are products of members of multigene families, but show specialization for plaque formation and intermediate filament attachment.
openaire   +2 more sources

Cadherin flexibility provides a key difference between desmosomes and adherens junctions

Proceedings of the National Academy of Sciences of the United States of America, 2015
Desmosomes and adherens junctions are intercellular adhesive structures essential for the development and integrity of vertebrate tissue, including the epidermis and heart.
Lydia Tabernero, Thomas Jowitt, David Garrod   +2 more
exaly   +2 more sources

Desmosomes at a glance

Journal of Cell Science
ABSTRACT Desmosomes are relatives of ancient cadherin-based junctions, which emerged late in evolution to ensure the structural integrity of vertebrate tissues by coupling the intermediate filament cytoskeleton to cell–cell junctions.
Abbey L. Perl, Jenny L. Pokorny, Kathleen J. Green   +2 more
openaire   +2 more sources