Results 171 to 180 of about 14,857 (218)

The transmembrane domain of the desmosomal cadherin desmoglein-1 governs lipid raft association to promote desmosome adhesive strength. [PDF]

Mol Biol Cell
Zimmer SE, Giang W, Levental I, Kowalczyk AP.   +3 more
europepmc   +1 more source

AI driven 3D subcellular RPE map discovers cell state transitions in establishment of apical-basal polarity. [PDF]

NPJ Artif Intell
Ortolan D, Sathe P, Volkov A, Reichert D, Sebastian S, Maminishkis A, Schaub NJ, Ljungquist B, Bose D, Ferrari J, Lin N, Pegoraro G, Simon CG, Sharma R, Bajcsy P, Bharti K.   +15 more
europepmc   +1 more source

A zebrafish stable model of Galectin-3 to elucidate its role in Arrhythmogenic Cardiomyopathy

Pilichou K, Risato G, Celeghin R, Cason M, Marinas MB, Pinci S, Casas RB, De Gaspari M, Barbera MD, Facchinello N, Rizzo S, Argenton F, Thiene G, Basso C, Tiso N.   +14 more
europepmc   +1 more source

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart. [PDF]

Journal of Cell Biology, 1996
Plakoglobin (gamma-catenin), a member of the armadillo family of proteins, is a constituent of the cytoplasmic plaque of desmosomes as well as of other adhering cell junctions, and is involved in anchorage of cytoskeletal filaments to specific cadherins.
V Brinkmann, Birgit Ledermann, Christine Grund   +2 more
exaly   +2 more sources

ISOLATION OF EPIDERMAL DESMOSOMES [PDF]

Journal of Cell Biology, 1974
A method is reported for the isolation of desmosomes in a high yield and of a purity suitable for biochemical analysis. The procedure utilizes the selective solubilizing action of citric acid-sodium citrate (CASC) buffer, pH 2.6, on the non-cornified layers of cow nose epidermis, followed by discontinuous sucrose density gradient centrifugation ...
A Gedeon Matoltsy, Christine J Skerrow
exaly   +3 more sources

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Desmosomal cadherins

Current Opinion in Cell Biology, 2002
New evidence from blocking desmosomal adhesion with anti-adhesion peptides reveals a role for desmosomes in cell positioning in morphogenesis. Desmosomal adhesion is necessary for the stability of adherens junctions in epithelial cell sheets. Knockout and mis-expression of desmosomal cadherins in mice suggests that they may function directly or ...
Garrod, David R., Merritt, Anita J., Nie, Zhuxiang   +2 more
openaire   +3 more sources

Cadherin flexibility provides a key difference between desmosomes and adherens junctions

Proceedings of the National Academy of Sciences of the United States of America, 2015
Desmosomes and adherens junctions are intercellular adhesive structures essential for the development and integrity of vertebrate tissue, including the epidermis and heart.
Jordi Bella, Thomas A Jowitt, Clair Baldock   +2 more
exaly   +2 more sources

Desmoplakin Is Required Early in Development for Assembly of Desmosomes and Cytoskeletal Linkage [PDF]

Journal of Cell Biology, 1998
Desmosomes first assemble in the E3.5 mouse trophectoderm, concomitant with establishment of epithelial polarity and appearance of a blastocoel cavity. Throughout development, they increase in size and number and are especially abundant in epidermis and ...
G Ian Gallicano, Panos Kouklis, Valeri Vasioukhin   +2 more
exaly   +1 more source

Desmosomes and hemidesmosomes

Current Opinion in Cell Biology, 1993
Desmosomes and hemidesmosomes are extremely different in their molecular composition. Most of the protein and glycoprotein components are products of members of multigene families, but show specialization for plaque formation and intermediate filament attachment.
openaire   +2 more sources