Results 61 to 70 of about 1,974 (174)

Preparation and Synthetic Applications of 8-Oxabicyclo[3.2.1]oct-6-en-3-one Derivatives

CHIMIA, 2008
The development of efficient routes to multi-gram quantities of chiral synthons is a key issue in the total synthesis of natural products and analogues.
Sylvain Favre, Sandrine Gerber-Lemaire, Pierre Vogel   +2 more
doaj   +1 more source

Synthesis of chiral sulfoximine-based thioureas and their application in asymmetric organocatalysis

Beilstein Journal of Organic Chemistry, 2012
For the first time, chiral sulfoximine derivatives have been applied as asymmetric organocatalysts. In combination with a thiourea-type backbone the sulfonimidoyl moiety leads to organocatalysts showing good reactivity in the catalytic desymmetrization ...
Marcus Frings, Isabelle Thomé, Carsten Bolm   +2 more
doaj   +1 more source

Evaluation of lipases in the desymmetrization of meso-exo-3,5-dihydroxymethylenetricyclo[5.2.1.0 2,6]decane and the synthesis of chiral derivatives

Journal of the Brazilian Chemical Society, 2004
meso-exo-3,5-dihydroxymethylenetricyclo[5.2.1.0(2,6)]decane was efficiently desymmetrized by the lipase from Pseudomonas cepacia (PS-C 'Amano' II) in vinyl acetate in high yields (93%) and with excellent enantiomeric excesses (ee > 99% by chiral GC ...
Costa Valentim E. U, Pohlmann Adriana R, Sordi Marli L. T. de   +2 more
doaj  

Access to Axially Chiral Aryl Aldehydes via Carbene-Catalyzed Nitrile Formation and Desymmetrization Reaction

Research
An approach utilizing N-heterocyclic carbene for nitrile formation and desymmetrization reaction is developed. The process involves kinetic resolution, with the axially chiral aryl monoaldehydes obtained in moderate yields with excellent optical purities.
Yuanlin Cai, Ya Lv, Liangzhen Shu, Zhichao Jin, Yonggui Robin Chi, Tingting Li   +5 more
doaj   +1 more source

Palladium-catalyzed desymmetric coupling reaction between silacyclobutanes and terminal alkynes for the synthesis of silicon-stereogenic allyl vinylsilanes

Tetrahedron Chem
A palladium/TADDOL-derived phosphonate catalyzed desymmetric ring-opening coupling bewteen prochiral silacyclobutanes and alkyl terminal alkynes was developed.
Zhi-Yuan Chen, Zi-Lu Wang, Jin-Bo Zhao, Yun-He Xu   +3 more
doaj   +1 more source

Procrystalline Self-Assembly of Desymmetrized Pentaphenylcyclopentadiene

The Journal of Physical Chemistry Letters
The interplay between the molecular shape and the intermolecular interaction plays a decisive role in self-assembled structures. Recently, inherent randomness of low ordered assemblies, resulting from lack of short- and long-range periodicities, has attracted significant attention due to the unique structural, electronic, and mechanical properties ...
Li, Donglin, Seki, Sota, Ishikawa, Atsushi, Omoto, Kenichiro, Yasuhara, Kazuma, Rapenne, Gwénaël, Kawai, Shigeki   +6 more
openaire   +4 more sources

Catalytic asymmetric desymmetrization of diesters: advances and perspectives

Tetrahedron Chem
Catalytic asymmetric desymmetrization of prochiral and meso-diesters has emerged as a powerful strategy for the synthesis of chiral compounds featuring tertiary or quaternary stereogenic carbon centers.
Yu Huang, Jia-Yu Liao
doaj   +1 more source

Enantioselective synthesis of chiral

Green Synthesis and Catalysis
The C–N axial chirality is widely present in natural products, bioactive molecules, and chiral ligands. Catalytic asymmetric construction of C–N axially chiral compounds is a challenging task due to the lower rotational barriers of the C–N bond. Here, we
Zi-Wei He, Dong Liang, Jia-Rong Chen, Ying Cheng, Wen-Jing Xiao   +4 more
doaj   +1 more source

Total Synthesis of 4-epi-Bengamide E

Molecules
Bengamide E is a bioactive natural product that was isolated from Jaspidae sponges by Crews and co-workers in 1989. It displays a wide range of biological activities, including antitumor, antibiotic, and anthelmintic properties.
Gabriella Vitali Forconesi, Andrea Basso, Luca Banfi, Davide Gugliotta, Chiara Lambruschini, Marta Nola, Renata Riva, Valeria Rocca, Lisa Moni   +8 more
doaj   +1 more source

Recent Advances in Enantioselective Desymmetrization Enabled by Chiral Phosphoric Acid Catalysis. [PDF]

Chirality
Zhang D, Xu B, Yang Y, Zhang D.
europepmc   +1 more source