Results 51 to 60 of about 1,974 (174)
Advanced ScienceAxially chiral diaryl ethers represent a distinct class of atropisomers, characterized by a unique dual C─O axes system, which have been found in a variety of natural products, pharmaceuticals, and ligands.
Zidan Ye +4 more
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A Short Method for the Synthesis of Alpha-Tocopherol Side Chain [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2007 The enzymatic hydrolysis of meso-1,7-diacetoxy-2,6-dimethylheptane 5, prepared from 2,6-dimethylhepta-1,6-diene 6, gave the (2S,6R)-7-acetoxy-2,6-dimethyl-1-heptanol 1, which was transformed to the (2R,6R)-2,6,10-trimethyl-1-undecanol 7.
Ghodsi Mohammadi Ziarani +2 more
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Nature Communications, 2018 Catalytic enantioselective synthesis of trifluoromethylthiolated molecules remains a challenge. Here, the authors report a bifunctional selenide-catalyzed approach for the synthesis of structurally complex chiral trifluoromethylthiolated ...
Jie Luo +3 more
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, 2014 Citation: 'desymmetrization step' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01624 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Desymmetrization of meso-bisphosphates using copper catalysis and alkylzirconocene nucleophiles
Nature Communications, 2019 Copper-catalyzed allylic desymmetrizations are, so far, limited to carbocyclic products with two tertiary stereocenters. Here, the authors report a highly enantioselective Cu-catalyzed desymmetrization of meso carbo- and hetero-cyclic bisphosphates to ...
Reece Jacques +2 more
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Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles
Nature Communications, 2019 Axially chiral arylpyrroles are structural motifs often found in natural and medicinal products. Here, the authors report the atroposelective synthesis of axially chiral arylpyrrole derivatives, which proved to be efficient chiral ligands for asymmetric ...
Lei Zhang +5 more
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Norbornanoid Chiral Ketones by Desymmetrization of Dibromoalkenes
Helvetica Chimica Acta, 2014 AbstractNew optically active polycyclic ketones 6a–6d, amenable to a large variety of synthetic applications, have been prepared from readily available 2,3‐dibromonorbornene and analogs (Scheme 2) via desymmetrization with (−)‐ephedrine, followed by hydrolysis under mild acidic conditions.
R. Kocak +3 more
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Stepwise Orthogonal Protection of Calix[4]arene Triamine: A Facile Route to Asymmetric Structures
MolbankA cone calix[4]arene having one tert-butyl group and three amino groups at the wide rim was bis-N-protected stepwise using sulfonylation with 4-nitrobenzylsulfonyl chloride, followed by acylation with di-tert-butyl dicarbonate.
Ivan Alekseev +4 more
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Advanced Science, 2019 The discovery of metal–organic frameworks (MOFs) mimicking inorganic minerals with intricate topologies requires elaborate linker design guidelines. Herein, the concept of linker desymmetrization into the design of tetratopic linker based Zr‐MOFs is ...
Yutong Wang +10 more
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Synthetic applications of the Cannizzaro reaction
Beilstein Journal of Organic ChemistryThe Cannizzaro reaction has emerged as a versatile synthetic tool for the construction of functionalized molecules. Dating back to the 19th century, this reaction, though initially used for the synthesis of an alcohol and acid functionality from ...
Bhaskar Chatterjee +2 more
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