Emerging Role of Targeting Deubiquitinating Enzymes to Inhibit Pathological Cardiac Hypertrophy. [PDF]
Liu RP, McMullen JR.
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A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway. [PDF]
Pauzaite T, Nathan JA.
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The C-degron pathway eliminates mislocalized proteins and products of deubiquitinating enzymes. [PDF]
Yeh CW +10 more
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The deubiquitinating enzymes-related signature predicts the prognosis and immunotherapy response in breast cancer. [PDF]
Deng Y +9 more
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Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients With Type 2 Diabetes. [PDF]
Dantas WS +12 more
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Deubiquitinating enzymes: potential regulators of the tumor microenvironment and implications for immune evasion. [PDF]
Hsu SK +5 more
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The Role of Deubiquitinating Enzymes in the Various Forms of Autophagy. [PDF]
Csizmadia T, Lőw P.
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Regulation of Deubiquitinating Enzymes by Post-Translational Modifications. [PDF]
Das T, Shin SC, Song EJ, Kim EE.
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Deubiquitinating enzyme YOD1 deubiquitinates and destabilizes α-synuclein
Biochemical and Biophysical Research Communications, 2023α-synuclein is one of the proteins involved in degenerative neuronal diseases such as Parkinson's disease (PD) or Lewy body dementia (LBD). The pathogenesis is imparted by the abnormal accumulation of α-synuclein resulting in the formation of a Lewy body (LB) and exerting neurotoxicity via an unknown mechanism.
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Enzymes of ubiquitination and deubiquitination
Essays in Biochemistry, 2012Ubiquitination, the covalent attachment of the small protein modifier ubiquitin to a substrate protein is involved in virtually all cellular processes by mediating the regulated degradation of proteins. Aside from proteasomal degradation, ubiquitination plays important roles in transcriptional regulation, protein trafficking, including endocytosis and ...
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