Results 21 to 30 of about 28,654 (213)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Streamlining Time Spent in Alternative Developmental Mathematics Pathways: Increasing Access to College-Level Mathematics Courses by Altering Placement Procedures

Journal of Mathematics Education at Teachers College, 2020
Developmental mathematics, which is designed to prepare students for college-level mathematics courses, can be a barrier to students’ success. In the United States, the majority of students placed into developmental mathematics courses fail to complete ...
Marla A. Sole
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Change and Relationships in Elementary Preservice Teachers’ Mathematics Pedagogical Beliefs, Teaching Efficacy Beliefs, and Content Knowledge

Proceedings of the Annual Meeting of the Georgia Association of Mathematics Teacher Educators, 2007
This study investigated the mathematics beliefs and content knowledge of 103 elementary preservice teachers in a developmental teacher preparation program that included a two course mathematics methods sequence.
Susan Swars, Lynn Hart, Stephanie Smith, Marvin Smith   +3 more
doaj   +1 more source

Emotions and mathematics: anxiety profiles and their influence on arithmetic performance in university students

Royal Society Open Science, 2023
Mathematics anxiety (MA), general and test anxieties affect mathematics performance. However, little is known about how different anxiety profiles (i.e.
Serena Rossi, Iro Xenidou-Dervou, Krzysztof Cipora   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Understanding Changes in Developmental Students’ Self-Efficacy Towards Mathematics: The Student Voice

Journal of College Academic Support Programs
Much work has been done to measure students’ self-efficacy towards mathematics. However, less attention has been given to reporting changes in self-efficacy among college developmental math students and even less to possible reasons for those changes ...
Lauren Cavner Williams, Kirk Weller
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Examining Math Instructors’ Knowledge, Beliefs, and Attitudes of Student Learning Strategies in a Faculty Development Workshop

Journal on Empowering Teaching Excellence, 2022
A faculty development workshop, focused on incorporating universal learning strategies into developmental mathematics courses, was created and utilized in a developmental mathematics department at an open-enrollment, mid-western university to ascertain ...
Roxanne Brinkerhoff, Becky Connelly, Sam Gedeborg   +2 more
doaj   +1 more source