Results 11 to 20 of about 1,176,068 (282)

Developmental disorders [PDF]

, 2002
Introduction: Connectionist models have recently provided a concrete computational platform from which to explore how different initial constraints in the cognitive system can interact with an environment to generate the behaviors we find in normal ...
Thomas, Michael S.C., Karmiloff-Smith, Annette   +1 more
core   +7 more sources

Integrating Cognitive Developmental Neuroscience in Society: Lessons Learned From a Multidisciplinary Research Project on Education and Social Safety of Youth. [PDF]

Front Integr Neurosci, 2021
Integrating fundamental science in society, with the goal to translate research findings to daily practice, comes with certain challenges. Successfully integrating research projects into society requires (1) good collaboration between scientists and ...
Vandenbroucke ARE, Crone EA, van Erp JBF, Güroğlu B, Hulshoff Pol HE, de Kogel CH, Krabbendam L, Jansen LMC, Brouwer AM.   +8 more
europepmc   +3 more sources

Raging Hormones: Why Age-Based Etiological Conceptualizations of the Development of Antisocial Behavior Are Insufficient

Frontiers in Behavioral Neuroscience, 2022
Developmental science, particularly developmental neuroscience, has substantially influenced the modern legal system. However, this science has typically failed to consider the role of puberty and pubertal hormones on development when considering ...
Stuart F. White, S. Mariely Estrada Gonzalez, Eibhlis M. Moriarty   +2 more
doaj   +1 more source

Translating Developmental Neuroscience to Substance Use Prevention [PDF]

Current Addiction Reports, 2015
Nathaniel Riggs
exaly   +2 more sources

Editorial: Social and Emotional Influences on Human Development: Perspectives From Developmental Neuroscience [PDF]

Frontiers in Psychology, 2018
Nicola Ferdinand, Markus Paulus, Tobias Schuwerk   +2 more
exaly   +2 more sources

Casein kinase 1α is required to maintain murine hypothalamic pro-opiomelanocortin expression

iScience, 2023
Summary: Hypothalamic pro-opiomelanocortin (POMC) neuron development is considered to play an essential role in the development of obesity. However, the underlying mechanisms remain unclear.
Chenyang Lu, Jinglin Zhang, Bingjie Wang, Qiao Gao, Kezhe Ma, Shaona Pei, Juxue Li, Sheng Cui   +7 more
doaj   +1 more source

Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF/TrkB signaling alterations

iScience, 2023
Summary: In Neurodevelopmental Disorders, alterations of synaptic plasticity may trigger structural changes in neuronal circuits involved in cognitive functions.
Martina Sgritta, Beatrice Vignoli, Domenico Pimpinella, Marilena Griguoli, Spartaco Santi, Andrzej Bialowas, Grzegorz Wiera, Paola Zacchi, Francesca Malerba, Cristina Marchetti, Marco Canossa, Enrico Cherubini   +11 more
doaj   +1 more source

FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migrations

iScience, 2023
Summary: Mutations in the human fasciculation and elongation protein zeta 1 (FEZ1) gene are found in schizophrenia and Jacobsen syndrome patients. Here, using human cerebral organoids (hCOs), we show that FEZ1 expression is turned on early during brain ...
Yinghua Qu, Jonathan Jun-Yong Lim, Omer An, Henry Yang, Yi-Chin Toh, John Jia En Chua   +5 more
doaj   +1 more source

Neonatal exposures to sevoflurane in rhesus monkeys alter synaptic ultrastructure in later life

iScience, 2022
Summary: Repeated or prolonged early life exposure to anesthesia is neurotoxic in animals and associated with neurocognitive impairment in later life in humans.
Tristan Fehr, William G.M. Janssen, Janis Park, Mark G. Baxter   +3 more
doaj   +1 more source

Unbiased characterization of the larval zebrafish enteric nervous system at a single cell transcriptomic level

iScience, 2023
Summary: The enteric nervous system (ENS) regulates many gastrointestinal functions including peristalsis, immune regulation and uptake of nutrients.
Laura E. Kuil, Naomi J.M. Kakiailatu, Jonathan D. Windster, Eric Bindels, Joke T.M. Zink, Gaby van der Zee, Robert M.W. Hofstra, Iain T. Shepherd, Veerle Melotte, Maria M. Alves   +9 more
doaj   +1 more source