Results 21 to 30 of about 1,182,997 (280)

The development of developmental neuroscience. [PDF]

J Neurosci, 2009
### Introduction Forty years ago in the emerging field of developmental neurobiology, neuroanatomists studied cellular development in their favorite brain region by annotating static Golgi preparations at different time points. Cell biologists examined how growth cones grow in tissue culture,
Mason C.
europepmc   +4 more sources

Neonatal exposures to sevoflurane in rhesus monkeys alter synaptic ultrastructure in later life

iScience, 2022
Summary: Repeated or prolonged early life exposure to anesthesia is neurotoxic in animals and associated with neurocognitive impairment in later life in humans.
Tristan Fehr, William G.M. Janssen, Janis Park, Mark G. Baxter   +3 more
doaj   +1 more source

Constructivist developmental theory is needed in developmental neuroscience. [PDF]

NPJ Sci Learn, 2016
AbstractNeuroscience techniques provide an open window previously unavailable to the origin of thoughts and actions in children. Developmental cognitive neuroscience is booming, and knowledge from human brain mapping is finding its way into education and pediatric practice.
Arsalidou M, Pascual-Leone J.
europepmc   +4 more sources

Unbiased characterization of the larval zebrafish enteric nervous system at a single cell transcriptomic level

iScience, 2023
Summary: The enteric nervous system (ENS) regulates many gastrointestinal functions including peristalsis, immune regulation and uptake of nutrients.
Laura E. Kuil, Naomi J.M. Kakiailatu, Jonathan D. Windster, Eric Bindels, Joke T.M. Zink, Gaby van der Zee, Robert M.W. Hofstra, Iain T. Shepherd, Veerle Melotte, Maria M. Alves   +9 more
doaj   +1 more source

The balance of rigor and reality in developmental neuroscience. [PDF]

Neuroimage, 2020
The balance realism and rigor in psychological research is essential to the development of rich and accurate theories about the developing brain. In the field of neuroimaging researchers have used predominantly controlled laboratory methods to decompose neural signals into meaningful functions but there is currently a push to integrate naturalistic ...
Cantlon JF.
europepmc   +5 more sources

Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity

iScience, 2021
Summary: Atypical cadherin Celsr3 is critical for brain embryonic development, and its role in the postnatal cerebellum remains unknown. Using Celsr3-GFP mice, Celsr3 shows high expression in postnatal Purkinje cells (PCs). Mice with conditional knockout
Qinji Zhou, Jingwen Qin, Yaying Liang, Wei Zhang, Siyuan He, Fadel Tissir, Yibo Qu, Libing Zhou   +7 more
doaj   +1 more source

The developmental profile of visual cortex astrocytes

iScience, 2023
Summary: We investigated how astrocytes in layer 5 mouse visual cortex mature over postnatal days (P) 3–50. Across this age range, resting membrane potential increased, input resistance decreased, and membrane responses became more passive with age.
Airi Watanabe, Connie Guo, Per Jesper Sjöström   +2 more
doaj   +1 more source

Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells

iScience, 2019
Summary: We report that cerebrum-specific inactivation of the histone deacetylase 3 (HDAC3) gene causes striking developmental defects in the neocortex, hippocampus, and corpus callosum; post-weaning lethality; and abnormal behaviors, including ...
Lin Li, Jianliang Jin, Xiang-Jiao Yang
doaj   +1 more source

Developmental cognitive neuroscience using Latent Change Score models: A tutorial and applications [PDF]

, 2017
Assessing and analysing individual differences in change over time is of central scientific importance to developmental neuroscience. However, the literature is based largely on cross-sectional comparisons, which reflect a variety of influences and ...
Ulman Lindenberger, Anne-Laura van Harmelen, Bullmore, E, JONES, Peter, Goodyer, I.M., Bullmore, E., FONAGY, Peter, Susanne M.M. de Mooij, Goodyer, I., Kievit, RA, Lindenberger, U., Ian M. Goodyer, DOLAN, Raymond J., Raymond J. Dolan, Brandmaier, A.M., Moutoussis, M., NSPN Consortium, Kievit, R. ; https://orcid.org/, Peter B. Jones, Fonagy, P., LINDENBERGER, Ulman, Dolan, RJ, Harmelen, A.L. van, Michael Moutoussis, Andreas M. Brandmaier, Mooij, S.M.M. de, GOODYER, Ian M., null null, MOUTOUSSIS, Michael, Brandmaier, AM, Susanne M. M. de Mooij, De Mooij, SMM, Gabriel Ziegler, Kievit, R.A., Moutoussis, M. ; https://orcid.org/, ZIEGLER, Gabriel, Lindenberger, U, Jones, P.B., Moutoussis, M, Ed Bullmore, KIEVIT, Rogier A., Peter Fonagy, Brandmaier, A. ; https://orcid.org/, Ian Goodyer, Rogier A. Kievit, Ziegler, G, Fonagy, P, Jones, PB, Dolan, R. ; https://orcid.org/, Goodyer, IM, BRANDMAIER, Andreas M., de Mooij, S., Dolan, R.J., Jones, P., BULLMORE, Ed, van Harmelen, A., Ziegler, G., Van Harmelen, AL, DE MOOIJ, Susanne M. M., VAN HARMELEN, Anne-Laura, Lindenberger, U. ; https://orcid.org/, Bullmore, E.T.   +61 more
core   +2 more sources

Theoretical Models of Neural Development

iScience, 2018
Constructing a functioning nervous system requires the precise orchestration of a vast array of mechanical, molecular, and neural-activity-dependent cues.
Geoffrey J. Goodhill
doaj   +1 more source