Results 21 to 30 of about 163,366 (294)

Opportunities for increased reproducibility and replicability of developmental neuroimaging [PDF]

open access: yes, 2020
Many workflows and tools that aim to increase the reproducibility and replicability of research findings have been suggested. In this review, we discuss the opportunities that these efforts offer for the field of developmental cognitive neuroscience, in ...
Tamnes, Christian K   +33 more
core   +1 more source

The developmental profile of visual cortex astrocytes

open access: yesiScience, 2023
Summary: We investigated how astrocytes in layer 5 mouse visual cortex mature over postnatal days (P) 3–50. Across this age range, resting membrane potential increased, input resistance decreased, and membrane responses became more passive with age.
Airi Watanabe   +2 more
doaj   +1 more source

16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis

open access: yesiScience, 2022
Summary: The complex 16p11.2 deletion syndrome (16pdel) is accompanied by neurological disorders, including epilepsy, autism spectrum disorder, and intellectual disability. We demonstrated that 16pdel iPSC differentiated neurons from affected people show
Danielle L. Tomasello   +7 more
doaj   +1 more source

Developmental cognitive neuroscience using Latent Change Score models: A tutorial and applications [PDF]

open access: yes, 2017
Assessing and analysing individual differences in change over time is of central scientific importance to developmental neuroscience. However, the literature is based largely on cross-sectional comparisons, which reflect a variety of influences and ...
Ulman Lindenberger   +60 more
core   +1 more source

Development and cadherin-mediated control of prefrontal corticostriatal projections in mice

open access: yesiScience, 2023
Summary: Action-outcome associations depend on prefrontal cortex (PFC) projections to the dorsal striatum. To assess how these projections form, we measured PFC axon patterning, synapse formation, and functional maturation in the postnatally developing ...
Roxana E. Mesías   +11 more
doaj   +1 more source

Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells

open access: yesiScience, 2019
Summary: We report that cerebrum-specific inactivation of the histone deacetylase 3 (HDAC3) gene causes striking developmental defects in the neocortex, hippocampus, and corpus callosum; post-weaning lethality; and abnormal behaviors, including ...
Lin Li, Jianliang Jin, Xiang-Jiao Yang
doaj   +1 more source

Theoretical Models of Neural Development

open access: yesiScience, 2018
Constructing a functioning nervous system requires the precise orchestration of a vast array of mechanical, molecular, and neural-activity-dependent cues.
Geoffrey J. Goodhill
doaj   +1 more source

Aberrant cortical projections to amygdala GABAergic neurons contribute to developmental circuit dysfunction following early life stress

open access: yesiScience, 2023
Summary: Early life stress (ELS) results in enduring dysfunction of the corticolimbic circuitry, underlying emotional and social behavior. However, the neurobiological mechanisms involved remain elusive.
Joni Haikonen   +10 more
doaj   +1 more source

Neuroblasts contribute to oligodendrocytes generation upon demyelination in the adult mouse brain

open access: yesiScience, 2022
Summary: After demyelinating insult, the neuronal progenitors of the adult mouse sub-ventricular zone (SVZ) called neuroblasts convert into oligodendrocytes that participate to the remyelination process.
Bilal El Waly   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy