Results 21 to 30 of about 389,547 (323)

Social re-orientation and brain development: An expanded and updated view. [PDF]

open access: yes, 2016
Social development has been the focus of a great deal of neuroscience based research over the past decade. In this review, we focus on providing a framework for understanding how changes in facets of social development may correspond with changes in ...
Guyer, Amanda E   +2 more
core   +8 more sources

Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity

open access: yesiScience, 2021
Summary: Atypical cadherin Celsr3 is critical for brain embryonic development, and its role in the postnatal cerebellum remains unknown. Using Celsr3-GFP mice, Celsr3 shows high expression in postnatal Purkinje cells (PCs). Mice with conditional knockout
Qinji Zhou   +7 more
doaj   +1 more source

Editorial: Developmental neuroscience comes of age [PDF]

open access: bronzeJournal of Child Psychology and Psychiatry, 2011
James F. Leckman, John S. March
openaire   +4 more sources

The developmental profile of visual cortex astrocytes

open access: yesiScience, 2023
Summary: We investigated how astrocytes in layer 5 mouse visual cortex mature over postnatal days (P) 3–50. Across this age range, resting membrane potential increased, input resistance decreased, and membrane responses became more passive with age.
Airi Watanabe   +2 more
doaj   +1 more source

How can neuroscience contribute to moral philosophy, psychology and education based on Aristotelian virtue ethics? [PDF]

open access: yes, 2016
The present essay discusses the relationship between moral philosophy, psychology and education based on virtue ethics, contemporary neuroscience, and how neuroscientific methods can contribute to studies of moral virtue and character. First, the present
Han, Hyemin
core   +2 more sources

16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis

open access: yesiScience, 2022
Summary: The complex 16p11.2 deletion syndrome (16pdel) is accompanied by neurological disorders, including epilepsy, autism spectrum disorder, and intellectual disability. We demonstrated that 16pdel iPSC differentiated neurons from affected people show
Danielle L. Tomasello   +7 more
doaj   +1 more source

Models of atypical development must also be models of normal development [PDF]

open access: yes, 2002
Functional magnetic resonance imaging studies of developmental disorders and normal cognition that include children are becoming increasingly common and represent part of a newly expanding field of developmental cognitive neuroscience. These studies have
Mareschal, D, Westermann, G
core   +1 more source

Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells

open access: yesiScience, 2019
Summary: We report that cerebrum-specific inactivation of the histone deacetylase 3 (HDAC3) gene causes striking developmental defects in the neocortex, hippocampus, and corpus callosum; post-weaning lethality; and abnormal behaviors, including ...
Lin Li, Jianliang Jin, Xiang-Jiao Yang
doaj   +1 more source

Development and cadherin-mediated control of prefrontal corticostriatal projections in mice

open access: yesiScience, 2023
Summary: Action-outcome associations depend on prefrontal cortex (PFC) projections to the dorsal striatum. To assess how these projections form, we measured PFC axon patterning, synapse formation, and functional maturation in the postnatally developing ...
Roxana E. Mesías   +11 more
doaj   +1 more source

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