Results 21 to 30 of about 1,316,154 (307)

A developmental neuroscience approach to the search for biomarkers in autism spectrum disorder. [PDF]

Curr Opin Neurol, 2016
Varcin KJ, Nelson CA.
europepmc   +2 more sources

Raging Hormones: Why Age-Based Etiological Conceptualizations of the Development of Antisocial Behavior Are Insufficient

Frontiers in Behavioral Neuroscience, 2022
Developmental science, particularly developmental neuroscience, has substantially influenced the modern legal system. However, this science has typically failed to consider the role of puberty and pubertal hormones on development when considering ...
Stuart F. White, S. Mariely Estrada Gonzalez, Eibhlis M. Moriarty   +2 more
doaj   +1 more source

Annual Research Review: Early intervention viewed through the lens of developmental neuroscience.

Journal of Child Psychology and Psychiatry and Allied Disciplines, 2023
The overarching goal of this paper is to examine the efficacy of early intervention when viewed through the lens of developmental neuroscience. We begin by briefly summarizing neural development from conception through the first few postnatal years.
C. Nelson, Eileen F. Sullivan, Anne-Michelle Engelstad   +2 more
semanticscholar   +1 more source

Casein kinase 1α is required to maintain murine hypothalamic pro-opiomelanocortin expression

iScience, 2023
Summary: Hypothalamic pro-opiomelanocortin (POMC) neuron development is considered to play an essential role in the development of obesity. However, the underlying mechanisms remain unclear.
Chenyang Lu, Jinglin Zhang, Bingjie Wang, Qiao Gao, Kezhe Ma, Shaona Pei, Juxue Li, Sheng Cui   +7 more
doaj   +1 more source

Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF/TrkB signaling alterations

iScience, 2023
Summary: In Neurodevelopmental Disorders, alterations of synaptic plasticity may trigger structural changes in neuronal circuits involved in cognitive functions.
Martina Sgritta, Beatrice Vignoli, Domenico Pimpinella, Marilena Griguoli, Spartaco Santi, Andrzej Bialowas, Grzegorz Wiera, Paola Zacchi, Francesca Malerba, Cristina Marchetti, Marco Canossa, Enrico Cherubini   +11 more
doaj   +1 more source

A Developmental Social Neuroscience Perspective on Infant Autism Interventions

Annual Review of Developmental Psychology, 2023
Research on early biomarkers and behavioral precursors of autism has led to interventions initiated during the infant period that could potentially change the course of infant brain and behavioral development in autism.
Geraldine Dawson, Amber D. Rieder, Mark H Johnson   +2 more
semanticscholar   +1 more source

FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migrations

iScience, 2023
Summary: Mutations in the human fasciculation and elongation protein zeta 1 (FEZ1) gene are found in schizophrenia and Jacobsen syndrome patients. Here, using human cerebral organoids (hCOs), we show that FEZ1 expression is turned on early during brain ...
Yinghua Qu, Jonathan Jun-Yong Lim, Omer An, Henry Yang, Yi-Chin Toh, John Jia En Chua   +5 more
doaj   +1 more source

A perspective on enhancing representative samples in developmental human neuroscience: Connecting science to society

Frontiers in Integrative Neuroscience, 2022
Marginalized groups are often underrepresented in human developmental neuroscientific studies. This is problematic for the generalizability of findings about brain-behavior mechanisms, as well as for the validity, reliability, and reproducibility of ...
Kayla H. Green, Ilse H. van de Groep, L. W. te Brinke, Renske van der Cruijsen, Fabienne van Rossenberg, H. El Marroun   +5 more
semanticscholar   +1 more source

Neonatal exposures to sevoflurane in rhesus monkeys alter synaptic ultrastructure in later life

iScience, 2022
Summary: Repeated or prolonged early life exposure to anesthesia is neurotoxic in animals and associated with neurocognitive impairment in later life in humans.
Tristan Fehr, William G.M. Janssen, Janis Park, Mark G. Baxter   +3 more
doaj   +1 more source

Unbiased characterization of the larval zebrafish enteric nervous system at a single cell transcriptomic level

iScience, 2023
Summary: The enteric nervous system (ENS) regulates many gastrointestinal functions including peristalsis, immune regulation and uptake of nutrients.
Laura E. Kuil, Naomi J.M. Kakiailatu, Jonathan D. Windster, Eric Bindels, Joke T.M. Zink, Gaby van der Zee, Robert M.W. Hofstra, Iain T. Shepherd, Veerle Melotte, Maria M. Alves   +9 more
doaj   +1 more source