Results 71 to 80 of about 389,547 (323)

Theories of the development of human communication [PDF]

, 2013
This article considers evidence for innate motives for sharing rituals and symbols from animal semiotics, developmental neurobiology, physiology of prospective motor control, affective neuroscience and infant communication. Mastery of speech and language
Delafield-Butt, Jonathan, Trevarthen, Colwyn   +1 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Development of sensorimotor-visual connectome gradient at birth predicts neurocognitive outcomes at 2 years of age

iScience
Summary: Functional connectome gradients represent fundamental organizing principles of the brain. Here, we report the development of the connectome gradients in preterm and term babies aged 31–42 postmenstrual weeks using task-free functional MRI and ...
Yunman Xia, Jianlong Zhao, Yuehua Xu, Dingna Duan, Mingrui Xia, Tina Jeon, Minhui Ouyang, Lina Chalak, Nancy Rollins, Hao Huang, Yong He   +10 more
doaj   +1 more source

Opportunities and challenges for current developmental neuroscience [PDF]

Theory & Psychology, 2016
While developmental neuroscience can often be motivated by clinical and policy concerns, its constituent research methodologies aim to provide insights into the limits and potential of the developing brain. Our article addresses two main approaches for characterizing psychological and neural changes that occur between infancy and adolescence ...
Steinbeis, N, Margulies, DS
openaire   +4 more sources

Only the strong survive: therapeutic selective pressure drives medulloblastoma leptomeningeal metastasis

Molecular Oncology, EarlyView.
Radiation therapy induces cancer cell death and immune cell infiltration, mainly monocytes, macrophages, and dendritic cells. Elevated serum cytokine levels and disruption of the blood–brain barrier promote leptomeningeal dissemination. Cotreatment with dexamethasone reduces cytokine levels, preserves barrier integrity, and limits metastatic spread ...
Francis Y. He, Adrienne Boire
wiley   +1 more source

Microbiota-dependent early-life programming of gastrointestinal motility

iScience
Summary: Gastrointestinal microbes modulate peristalsis and stimulate the enteric nervous system (ENS), whose development, as in the central nervous system (CNS), continues into the murine postweaning period.
Mary E. Frith, Purna C. Kashyap, David R. Linden, Betty Theriault, Eugene B. Chang   +4 more
doaj   +1 more source

Developmental change in predictive motor abilities

iScience, 2023
Summary: Prediction is critical for successful interactions with a dynamic environment. To test the development of predictive processes over the life span, we designed a suite of interceptive tasks implemented as interactive video games.
Se-Woong Park, Annie Cardinaux, Dena Crozier, Marta Russo, Margaret Kjelgaard, Pawan Sinha, Dagmar Sternad   +6 more
doaj   +1 more source

Sensory over-responsivity and social cognition in ASD: Effects of aversive sensory stimuli and attentional modulation on neural responses to social cues. [PDF]

, 2018
Sensory over-responsivity (SOR) is a common condition in autism spectrum disorders (ASD) that is associated with greater social impairment. However, the mechanisms through which sensory stimuli may affect social functioning are not well understood.
Bookheimer, Susan Y, Bowman, Hilary C, Dapretto, Mirella, Green, Shulamite A, Hernandez, Leanna M   +4 more
core   +2 more sources

Anxious to see you: Neuroendocrine mechanisms of social vigilance and anxiety during adolescence. [PDF]

, 2020
Social vigilance is a behavioral strategy commonly used in adverse or changing social environments. In animals, a combination of avoidance and vigilance allows an individual to evade potentially dangerous confrontations while monitoring the social ...
Cassano G. B., Gegenhuber B., Hollingworth S. A., Marler C. A., Park J., Pickett C. L., Williamson C. M.   +6 more
core   +1 more source

Developmental aspects in cultural neuroscience

Developmental Review, 2018
Research in cultural neuroscience and development examines the processes and mechanisms underlying the interaction of cultural systems with environmental and biological systems with a life course approach. Culture interacts with environmental and biological factors to shape the mind, brain and behavior across stages of development.
openaire   +4 more sources