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Male-mediated developmental toxicity [PDF]
Asian Journal of Andrology, 2014 Male-mediated developmental toxicity has been of concern for many years. The public became aware of male-mediated developmental toxicity in the early 1990s when it was reported that men working at Sellafield might be causing leukemia in their children ...
Diana Anderson +2 more
doaj +5 more sources
A Scoping Review on Male-Mediated Developmental Toxicity [PDF]
ToxicsBackground: Developmental toxicity is defined as adverse effects induced either during pregnancy or as a result of parental exposure. While considerable attention has been devoted to maternal exposure to such chemicals, the role of paternal exposure has ...
Lidia Caporossi +3 more
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CAESAR models for developmental toxicity [PDF]
Chemistry Central Journal, 2010 Background The new REACH legislation requires assessment of a large number of chemicals in the European market for several endpoints. Developmental toxicity is one of the most difficult endpoints to assess, on account of the complexity, length and costs ...
Piclin Nadège +7 more
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Transcriptomics in developmental toxicity testing [PDF]
EXCLI journal, 2013 EXCLI Journal ; Vol.
Bolt, H. M.
core +4 more sources
Using Zebrafish to Screen Developmental Toxicity of Per- and Polyfluoroalkyl Substances (PFAS) [PDF]
ToxicsPer- and polyfluoroalkyl substances (PFAS) are found in many consumer and industrial products. While some PFAS, notably perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS), are developmentally toxic in mammals, the vast majority of PFAS
Katy N. Britton +9 more
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An oral developmental toxicity study of generic pesticide pinoxaden in rabbits [PDF]
Toxicology ReportsThe safety assessment of pinoxaden by the Joint Meeting on Pesticide Residues (JMPR) established a NOAEL of 30 mg/kg bw/day for maternal and embryo/fetal toxicity from a rabbit developmental toxicity study.
Inna Rashkivska +5 more
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Male-Mediated Developmental Toxicity [PDF]
Annual Review of Public Health, 1993 The etiology of many of the adverse reproductive outcomes among humans is not well understood. Most epidemiologic and laboratory research focuses on maternal factors. Studies of such adverse developmental outcomes as spontaneous abortion, low birthweight, and birth defects have assessed maternal drug, smoking, alcohol, infectious, and occupational ...
A F, Olshan, E M, Faustman
openaire +3 more sources
Ecotoxicology and Environmental Safety, 2022 Polybrominated biphenyls (PBBs) can bioaccumulate in nature and are toxic to humans. Long-time exposure to PBBs in pregnant women can lead to the birth of an infant with abnormal conditions.
Luze Yang +3 more
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Cardiac developmental toxicity [PDF]
Birth Defects Research Part C: Embryo Today: Reviews, 2011 AbstractCongenital heart disease (CHD) is a highly prevalent problem with mostly unknown origins. Many cases of CHD likely involve an environmental exposure coupled with genetic susceptibility, but practical and ethical considerations make nongenetic causes of CHD difficult to assess in humans.
Gretchen J, Mahler, Jonathan T, Butcher
openaire +2 more sources
Effects of Decamethylcyclopentasiloxane on Reproductive Systems in Female Rats
Toxics, 2023 The female reproductive system becomes fertile through the action of hormones involved in the hypothalamic-pituitary-ovarian axis. On the other hand, estrogen-like endocrine disruptors released into the environment come into contact with humans by ...
Jimin Lee +4 more
doaj +1 more source