Results 21 to 30 of about 275,688 (307)

Male-mediated developmental toxicity [PDF]

Toxicology and Applied Pharmacology, 2005
In recent years, the public has become more aware that exposure of males to certain agents can adversely affect their offspring and cause infertility and cancer. The hazards associated with exposure to ionising radiation have been recognised for nearly a century, but interest was aroused when a cluster of leukaemia cases was identified in young ...
openaire   +3 more sources

Prenatal ethanol exposure and changes in fetal neuroendocrine metabolic programming

Biological Research, 2023
Prenatal ethanol exposure (PEE) (mainly through maternal alcohol consumption) has become widespread. However, studies suggest that it can cause intrauterine growth retardation (IUGR) and multi-organ developmental toxicity in offspring, and susceptibility
Liang Liu, Yinxian Wen, Qubo Ni, Liaobin Chen, Hui Wang   +4 more
doaj   +1 more source

Developmental toxicity of bromoacetamide via the thyroid hormone receptors-mediated disruption of thyroid hormone homeostasis in zebrafish embryos

Ecotoxicology and Environmental Safety, 2022
Bromoacetamide (BAcAm) is a nitrogenous disinfection by-product. We previously found that BAcAm induced developmental toxicity in zebrafish embryos, but the underlying mechanisms remain to be elucidated.
Wei Wang, Qiyao Ma, Xinliang Ding, Yihua Xu, Mengting He, Jie Xu, Jianjun Liu, Cheng Ji, Jie Zhang   +8 more
doaj   +1 more source

Developmental toxicity of bisphenol A diglycidyl ether (epoxide resin badge) during the early life cycle of a native amphibian species [PDF]

, 2016
Bisphenol A diglycidyl ether (BADGE) is used in packaging materials, in epoxy adhesives, and as an additive for plastics, but it is also a potential industrial wastewater contaminant.
Andersen, Ballesteros-Gómez, Bantle, Beebee, Biedermann, Del Conte, Denoël, Di Rienzo, Durando, Edginton, Ferrari, Hammarling, Herkovits, Herkovits, Herkovits, Hutler Wolkowicz, Hutler Wolkowicz, Mann, Olea, Pisanó, Poole, Pérez-Coll, Räsänen, Sandermann, Semlitsch, Steiner, Stoker, Suárez, Terasaki, Uematsu, Un-jun, Yang   +31 more
core   +1 more source

Building a developmental toxicity ontology [PDF]

Birth Defects Research, 2018
BackgroundAs more information is generated about modes of action for developmental toxicity and more data are generated using high‐throughput and high‐content technologies, it is becoming necessary to organize that information. This report discussed the need for a systematic representation of knowledge about developmental toxicity (i.e., an ontology ...
Nancy Baker, Alan Boobis, Lyle Burgoon, Edward Carney, Richard Currie, Ellen Fritsche, Thomas Knudsen, Madeleine Laffont, Aldert H. Piersma, Alan Poole, Steffen Schneider, George Daston   +11 more
openaire   +5 more sources

Combination of the BeWo b30 placental transport model and the embryonic stem cell test to assess the potential developmental toxicity of silver nanoparticles

Particle and Fibre Toxicology, 2020
Background Silver nanoparticles (AgNPs) are used extensively in various consumer products because of their antimicrobial potential. This requires insight in their potential hazards and risks including adverse effects during pregnancy on the developing ...
Ashraf Abdelkhaliq, Meike van der Zande, Ruud J. B. Peters, Hans Bouwmeester   +3 more
doaj   +1 more source

In Vitro Consequences of Electronic-Cigarette Flavoring Exposure on the Immature Lung. [PDF]

, 2019
Background: The developing lung is uniquely susceptible and may be at increased risk of injury with exposure to e-cigarette constituents. We hypothesize that cellular toxicity and airway and vascular responses with exposure to flavored refill solutions ...
Berkelhamer, Sara, Goniewicz, Maciej, Gugino, Sylvia, Helman, Justin, Lakshminrusimha, Satyanarayana, Leigh, Noel   +5 more
core   +2 more sources

Developmental toxicity of Zishen Guchong Pill on the early life stages of Zebrafish

Phytomedicine Plus, 2021
Background: Zishen Guchong Pill (ZGP), a traditional oriental herbal medicine, has been applied broadly in the treatment of threatened or recurrent miscarriages in clinics, but little is known about its developmental toxicity.Aim of the study: This study
Jiazhen Wang, Cailian Mo, Pengfei Tu, Na Ning, Xin Liu, Shenghua Lin, Sellamani Muthulakshmi, Zixin He, Yun Zhang, Kechun Liu, Qiuxia He   +10 more
doaj   +1 more source

Review of QSAR Models and Software Tools for Predicting Developmental and Reproductive Toxicity [PDF]

, 2010
This report provides a state-of-the-art review of available computational models for developmental and reproductive toxicity, including Quantitative Structure-Activity Relationship (QSARs) and related estimation methods such as decision tree approaches ...
LO PIPARO ELENA, WORTH Andrew
core   +1 more source

Methanol and isopropanol embryo dosage response curves for wild-type and ethanol-sensitive zebrafish [PDF]

, 2016
It is well established that ethanol has an array of negative effects on developing embryos, from craniofacial abnormalities to cognitive deficits and behavioral disorders.
Anderson, Ashley
core   +1 more source