Results 21 to 30 of about 63,586 (320)

Dexmedetomidine for patients with croup

open access: yesRespiratory Medicine Case Reports, 2021
Agitation exacerbates symptoms in patients with croup, but the reports on the therapeutic effects of sedation in these patients without intubation are scarce. We describe a typical case of croup wherein light sedation with dexmedetomidine was effective in treating and discuss how agitation exacerbates and sedation improves symptoms from the viewpoint ...
Norihiko Tsuboi   +4 more
openaire   +4 more sources

Safe electrophysiologic profile of dexmedetomidine in different experimental arrhythmia models

open access: yesScientific Reports, 2021
Previous studies suggest an impact of dexmedetomidine on cardiac electrophysiology. However, experimental data is sparse. Therefore, purpose of this study was to investigate the influence of dexmedetomidine on different experimental models of ...
Christian Ellermann   +9 more
doaj   +1 more source

Incidence of acute kidney injury after noncardiac surgery in patients receiving intraoperative dexmedetomidine: a retrospective study

open access: yesBJA Open, 2023
Background: Postoperative acute kidney injury (AKI) is a common complication and is associated with increased hospital length of stay and 30 day all-cause mortality.
Manuel A. Paredes-Flores   +10 more
doaj   +1 more source

Clinically relevant concentrations of dexmedetomidine may reduce oxytocin-induced myometrium contractions in pregnant rats [PDF]

open access: yesAnesthesia and Pain Medicine, 2020
Background Recently, there have been some trials to use dexmedetomidine in the obstetric field but concerns regarding the drug include changes in uterine contractions after labor.
Dong Joon Kim   +5 more
doaj   +1 more source

Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine

open access: yesClinical Pharmacokinetics, 2017
Dexmedetomidine is an α2-adrenoceptor agonist with sedative, anxiolytic, sympatholytic, and analgesic-sparing effects, and minimal depression of respiratory function.
Maud A. S. Weerink   +5 more
semanticscholar   +1 more source

Effect of Intraoperative Dexmedetomidine on Recovery of Gastrointestinal Function After Abdominal Surgery in Older Adults

open access: yesJAMA Network Open, 2021
Key Points Question Does the intraoperative administration of dexmedetomidine accelerate the recovery of gastrointestinal function among older patients undergoing abdominal surgery? Findings In this randomized clinical trial of 808 patients aged 60 years

semanticscholar   +1 more source

The Effect of Dexmedetomidine on Postoperative Nausea and Vomiting in Patients Undergoing Thoracic Surgery-A Meta-Analysis of a Randomized Controlled Trial

open access: yesFrontiers in Surgery, 2022
BackgroundDexmedetomidine reduces the occurrence of postoperative nausea and vomiting (PONV); however, the effect of dexmedetomidine on PONV in patients undergoing thoracic surgery remains inconclusive.
Wei Zhang   +5 more
doaj   +1 more source

Dexmedetomidine in Enhanced Recovery After Surgery (ERAS) Protocols for Postoperative Pain

open access: yesCurrent Pain and Headache Reports, 2020
Purpose of Review Effective acute pain management has evolved considerably in recent years and is a primary area of focus in attempts to defend against the opioid epidemic.
A. Kaye   +8 more
semanticscholar   +1 more source

Dexmedetomidine-induced contraction of isolated rat aorta is dependent on extracellular calcium concentration [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
BackgroundDexmedetomidine is a highly selective α2-adrenoceptor agonist that is widely used for sedation and analgesia during the perioperative period. Intravenous administration of dexmedetomidine induces transient hypertension due to vasoconstriction ...
Seong-Ho Ok   +3 more
doaj   +1 more source

Early Sedation with Dexmedetomidine in Critically Ill Patients.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Dexmedetomidine produces sedation while maintaining a degree of arousability and may reduce the duration of mechanical ventilation and delirium among patients in the intensive care unit (ICU).
Y. Shehabi   +13 more
semanticscholar   +1 more source

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