Results 131 to 140 of about 98,007 (275)
The Effects Of 5-Ht4 Receptor Agonists On Interleukin-10 Knockout Mice [PDF]
, 2018 Recent studies have demonstrated that activation of the 5-HT4 receptors in the colonic mucosa can have healing and protective actions in experimental models of colitis.
Mylie, Quentin
core +1 more source
Increased calcification by erythrophagocytosis in aortic valvular interstitial cells
ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin +3 more
wiley +1 more source
The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]
, 2015 OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G +5 more
core
Food Bioengineering, EarlyView.ABSTRACT Bitter melon polysaccharides (BMPs), a key bioactive component of bitter melon, exhibit a range of biological activities including gut microbiota regulation, immune modulation, and antioxidant activity. Based on previous evidence of its protective effect on the colonic mucus barrier under high‐fat‐diet condition, this study evaluated the ...
Tangying Kang +6 more
wiley +1 more source
Determination of chain conformation of polysaccharides using a SEC‐MALLS‐Vis
Food Biomacromolecules, EarlyView.Abstract For polysaccharides, biological activity is associated with the chemical structure as well as the chain conformation. The chain conformation is conventionally derived from the scaling relationships between weight‐average molecular weight (Mw) and intrinsic viscosity ([η]) or the radius of gyration (Rg) or the translational diffusion ...
Xuan Li +3 more
wiley +1 more source
Food Safety and Health, EarlyView.ABSTRACT Currently, small‐molecular‐weight collagen peptides are a research hotspot in functional factor development due to their high bioavailability and diverse bioactivities. In this study, gelatin was extracted from tilapia (Oreochromis niloticus) scales by hot water extraction, followed by pepsin hydrolysis and ultrafiltration to obtain the < 3 ...
Ya‐ru Liu +5 more
wiley +1 more source
Overexpression of alpha(1)-acid glycoprotein in transgenic mice leads to sensitisation to acute colitis. [PDF]
, 2002 BAUMANN, H +6 more
core +2 more sources
Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae
Interdisciplinary Medicine, EarlyView.A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang +10 more
wiley +1 more source
Interdisciplinary Medicine, EarlyView.Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li +24 more
wiley +1 more source