Results 41 to 50 of about 78,284 (308)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Mouse Model of Dextran Sodium Sulfate (DSS)-induced Colitis

Bio-Protocol, 2017
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestinal tract and is primarily comprised of Crohn’s disease (CD) and ulcerative colitis (UC).
Srustidhar Das, Surinder K. Batra, Satyanarayana Rachagani   +2 more
doaj   +1 more source

Shape Memory Microneedle to Prevent Risks of Reproductive Hormone Therapy by Switching Sustained to Burst Release Under a Single Transdermal Insertion

Advanced Functional Materials, EarlyView.
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho, Hyunjae Kim, Seung Eun Yu, Sangmin Lee, Ji Youn Lee, Mi‐Lan Kang, Kang Suk Lee, Young Sik Choi, Hak‐Joon Sung   +8 more
wiley   +1 more source

Dextran Sulfate Sodium Salt-Induced Colitis Aggravates Gut Microbiota Dysbiosis and Liver Injury in Mice With Non-alcoholic Steatohepatitis

Frontiers in Microbiology, 2021
Objective: Inflammatory bowel disease (IBD) is characterized by gut microbiota dysbiosis, which is also frequently observed in patients with non-alcoholic fatty liver disease.
Bo Shen, Bo Shen, Junjun Wang, Junjun Wang, Yuecheng Guo, Yuecheng Guo, Tianyi Gu, Tianyi Gu, Zhenyang Shen, Zhenyang Shen, Cui Zhou, Cui Zhou, Binghang Li, Binghang Li, Xianjun Xu, Xianjun Xu, Fei Li, Fei Li, Qidi Zhang, Qidi Zhang, Xiaobo Cai, Xiaobo Cai, Hui Dong, Hui Dong, Lungen Lu, Lungen Lu   +25 more
doaj   +1 more source

Adhesion of Mycoplasma pneumoniae to Sulfated Glycolipids and Inhibition by Dextran Sulfate

Journal of Biological Chemistry, 1989
A virulent strain of Mycoplasma pneumoniae was metabolically labeled with [3H]palmitate and studied for binding to glycolipids and to WiDr human colon adenocarcinoma cells. The organism binds strongly to sulfatide and other sulfated glycolipids, such as seminolipid and lactosylsulfatide which all contain terminal Gal(3SO4) beta 1-residues and weakly to
H C, Krivan, L D, Olson, M F, Barile, V, Ginsburg, D D, Roberts   +4 more
openaire   +2 more sources

Effect of dextran sulfate on trimer purification via PGT145.

, 2019
(A) Aliquots of 2G12/SEC-purified BG505 SOSIP.664 trimers was incubated with dextran sulfate and then passed down a PGT145 column, with the yields recorded as a percentage of the initial amount (300 μg).
John P. Moore (260880), Anila Yasmeen (460713), Victor M. Cruz Portillo (4839432), Paul Gelfand (6564815), Albert Cupo (409522), P. J. Klasse (338325)   +5 more
core   +1 more source

Preparation and characterization of SDF-1α-chitosan-dextran sulfate nanoparticles [PDF]

, 2015
Chitosan (CS) and dextran sulfate (DS) are charged polysaccharides (glycans), which form polyelectrolyte complex-based nanoparticles when mixed under appropriate conditions.
Wang, W, Loscalzo, J, Kohane, DS, Zhang, YY, Li, T, Bader, AR   +5 more
core   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Stabilizing Water-in-Water Emulsions Using Oil Droplets

Molecules
The production of water-in-water emulsion droplets, the coalescence of which is prevented by adding oil-in-water micrometric droplets, is reported. Hexadecane (O) and cetyl trimethyl ammonium bromide (CTAB) were added to a W/W emulsion made of dextran ...
Jean-Paul Douliez, Laure Béven
doaj   +1 more source