Results 61 to 70 of about 78,284 (308)

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Effects of incubation of CS6 protein and recombinant CS6-expressing E. coli with dextran and dextran sulfate.

open access: yes, 2013
Radiolabeled CS6 protein and recombinant CS6-expressing bacteria were incubated with dextran or dextran sulfate (0.01–1 mg/ml) for 1 h at room temperature.
Catharina Jarefjäll (374514)   +5 more
core   +1 more source

The mouse CRC model was induced using the azoxymethane/dextran sulfate sodium salt method.

open access: yes, 2023
The mouse CRC model was induced using the azoxymethane/dextran sulfate sodium salt method.
Jinhua Tian (5655472)   +8 more
core   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro   +7 more
wiley   +1 more source

Effects of Chondroitin Sulfate on Colitis Induced by Dextran Sulfate Sodium in Rats

open access: yesJapanese Journal of Pharmacology, 2001
Chondroitin sulfate (CS) is currently marketed as a therapeutic drug for neurodynia, lumbago and arthrodynia. Recently, many clinical studies have demonstrated the therapeutic effects of orally administered CS against diseases with inflammation. Furthermore, these reports suggest CS plays an important role in the protection of the base of ulcers and ...
Hori, Yusuke   +5 more
openaire   +3 more sources

Carbon 60 Dissolved in Grapeseed Oil Inhibits Dextran Sodium Sulfate-Induced Experimental Colitis

open access: yes, 2022
Rayko Lazcano-Silveira,1 Xiaoxiao Jia,1 Kaixuan Liu,2 Honggang Liu,2 Xinrong Li,2 Mizhou Hui1 1College of Life Sciences, Northeast Agricultural University, Harbin, Heilongjiang, People’s Republic of China; 2College of Animal Science and Technology ...
Liu H   +5 more
core  

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

open access: yesAdvanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu   +10 more
wiley   +1 more source

TDAG51 deficiency attenuates dextran sulfate sodium-induced colitis in mice

open access: yesScientific Reports, 2022
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease, is a group of chronic inflammatory diseases of the gastrointestinal tract.
Hyoeun Jeon   +5 more
doaj   +1 more source

Electrolyte Additive Strategies in Aqueous Zn‐Ion Batteries: Recent Advances and Prospects

open access: yesAdvanced Science, EarlyView.
This article provides a comprehensive overview of the current status and future development directions of AZIBs electrolyte additives in three aspects: stabilizing zinc anodes (uniform deposition, inhibition of dendritic crystals), protecting cathodes (structural stability, inhibition of dissolution), and enhancing electrolyte stability (wider ...
Yuanze Yu   +7 more
wiley   +1 more source

Effects of dextran sulfate, 4-t-butylcyclohexanol, pongamia oil and hesperidin methyl chalcone on inflammatory and vascular responses implicated in rosacea

open access: yesClinical, Cosmetic and Investigational Dermatology, 2018
Hélène Hernandez-Pigeon, Lucile Garidou, Marie‑Florence Galliano, Hélène Delga, Marie‑Françoise Aries, Hélène Duplan, Sandrine Bessou-Touya, Nathalie Castex-Rizzi Department of Pharmacology, Pierre ...
Hernandez-Pigeon H   +7 more
doaj  

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