Results 51 to 60 of about 650,495 (350)

Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation [PDF]

, 2016
Although defects in intestinal barrier function are discussed as a key pathogenic factor in patients with inflammatory bowel diseases (IBD), the molecular pathways driving disease-specific alterations of intestinal epithelial cells (IECs) are largely ...
Alastair J.M. Watson, Arif B. Ekici, Becker, Christoph Becker, Claudia Günther, Cord Brakebusch, Distler, Gionata Fiorino, Heller, Hopkins, Imke Atreya, Kerstin Amann, Lin, Markus F. Neurath, Martin Bergö, Ohkusa, Pastorelli, Pechlivanis, Raja Atreya, Rocío López-Posadas, Silvio Danese, Stefan Tenzer, Stefan Wirtz, Stefania Vetrano, Turcotte, Ulrike Billmeier, Veronika Thonn, Zverina   +27 more
core   +1 more source

Effects of the sulfated polysaccharides dextran sulfate and heparin on shrimp immunity and infection by white spot syndrome virus and Vibrio parahaemolyticus

Aquaculture Reports
White spot syndrome virus (WSSV) and Vibrio parahaemolyticus are major pathogens of the economically important shrimp, Litopenaeus vannamei, causing white spot syndrome and hepatopancreatic necrosis disease (AHPND), respectively.
Soraat Amphan, Pasunee Laohawutthichai, Thapanan Jatuyosporn, Premruethai Supungul, Anchalee Tassanakajon, David G. Fernig, Kuakarun Krusong   +6 more
doaj   +1 more source

Alleviating Effect and Mechanism of Boletus edulis Extract on Dextran Sodium Sulfate-Induced Enteritis in Mice [PDF]

Shipin Kexue
This study systematically investigated the alleviating effect and underlying mechanism of Boletus edulis extract on dextran sodium sulfate-induced enterocolitis in mice. An integrated approach combining ultra-high performance liquid chromatography-tandem
CHANG Guofei, SHI Xiaoyu, CHENG Qin, ZENG Rongye, CHEN Tianzhen, HUANG Kailan, ZHANG Ming, ZHANG Xiuqing, MA Xiao
doaj   +1 more source

Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo [PDF]

, 2015
Objective: Gut homing of lymphocytes via adhesion molecules has recently emerged as new target for therapy in inflammatory bowel diseases. We aimed to analyze the in vivo homing of effector (Teff) and regulatory (Treg) T cells to the inflamed gut via ...
Agace, Alastair Watson, Anika Fischer, Atreya, Babyatsky, Baumgart, Canavan, Caroline Voskens, Christoph Becker, Clemens Neufert, Danese, Desreumaux, Dustin, Egawa, Fantini, Feagan, Fuss, Gerlach, Gerold Schuler, Ghosh, Haddad, Hamann, Hesterberg, Hoshino, Imke Atreya, Jovani, Kanai, Kempster, Kim, Ley, Li, Macdonald, Markus F Neurath, Matsuzaki, Maul, Neurath, Neurath, Nguyen, Nourshargh, Oki, Papadakis, Picarella, Podolsky, Pryde, Raja Atreya, Rocío López-Posadas, Rott, Rutgeerts, Sandborn, Sandborn, Sebastian Zundler, Shultz, Simon Hirschmann, Strober, Thomas, Tidswell, Timo Rath, Van Assche, Vermeire, Villablanca, Wang, Weninger, Wirtz, Wyant, Wyant   +64 more
core   +1 more source

Transport of Dextran Sulfates to Rat Livers

Japanese Journal of Pharmacology, 1979
Liver subcellular distributions of three different dextran sulfates (DSs) with average molecular weight (AMW) of 3000, 20,000, and 200,000, and sulfur content of 18%, anticoagulants and antilipemic agents, were examined in rats after intravenous administration of 50 mg/kg.
K, Kagawa, S, Tomizawa
openaire   +2 more sources

Anti-Inflammatory and Intestinal Microbiota Modulation Properties of Jinxiang Garlic (Allium sativum L.) Polysaccharides toward Dextran Sodium Sulfate-Induced Colitis.

Journal of Agricultural and Food Chemistry, 2020
Garlic polysaccharides are great potential agents because of their anti-inflammation, antioxidation, and immunomodulation properties. However, few studies have reported their anti-inflammatory effects on improving the colon system and corresponding ...
Xin Shao, Chongzheng Sun, Xin Tang, Xiaosa Zhang, Duo Han, Shan Liang, Rong Qu, Xiaodan Hui, Yangwei Shan, Linhui Hu, Heng Fang, Huidan Zhang, Xiyang Wu, Chunbo Chen   +13 more
semanticscholar   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Protective and Aggravating Effects of Nlrp3 Inflammasome Activation in IBD Models: Influence of Genetic and Environmental Factors [PDF]

, 2012
Background: Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation due to dysregulation of the mucosal immune system.
Bauer, Christian, Düwell, Peter, Endres, Stefan, Lehr, Hans-Anton, Schnurr, Max   +4 more
core   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Factors affecting synthesis of silver-nanoparticles and antimicrobial applications

Tạp chí Khoa học Đại học Huế: Khoa học Tự nhiên, 2020
Silver nanoparticles were synthesized from silver sulfate by using the chemical reduction method with dextran as both a reducing agent and a protective agent.
Phuong My Ton Nu, Nguyen Thi Thanh Hai, Nguyen Thi Thu Thuy, Nguyen Vinh Phu, Nguyen Thi Huong, Doan Thi Hang Nga, Ha Xuan Quoc Huy, Tran Thai Hoa   +7 more
doaj   +1 more source