Results 21 to 30 of about 809,717 (207)
Effects of Chondroitin Sulfate on Colitis Induced by Dextran Sulfate Sodium in Rats
Japanese Journal of Pharmacology, 2001 Chondroitin sulfate (CS) is currently marketed as a therapeutic drug for neurodynia, lumbago and arthrodynia. Recently, many clinical studies have demonstrated the therapeutic effects of orally administered CS against diseases with inflammation. Furthermore, these reports suggest CS plays an important role in the protection of the base of ulcers and ...
Hori, Yusuke +5 more
openaire +3 more sources
Molecular Pain, 2017 Background Curcumin has been reported to have anti-inflammatory and anti-nociceptive effects. The present study was designed to explore the potential therapeutic effects of curcumin on visceral hyperalgesia and inflammation in a rat model of ulcerative ...
Mei Yang +5 more
doaj +1 more source
Alleviating Effect and Mechanism of Boletus edulis Extract on Dextran Sodium Sulfate-Induced Enteritis in Mice [PDF]
Shipin KexueThis study systematically investigated the alleviating effect and underlying mechanism of Boletus edulis extract on dextran sodium sulfate-induced enterocolitis in mice. An integrated approach combining ultra-high performance liquid chromatography-tandem
CHANG Guofei, SHI Xiaoyu, CHENG Qin, ZENG Rongye, CHEN Tianzhen, HUANG Kailan, ZHANG Ming, ZHANG Xiuqing, MA Xiao
doaj +1 more source
Preparation of Risedronate Nanoparticles by Solvent Evaporation Technique
Molecules, 2014 One approach for the enhancement of oral drug bioavailability is the technique of nanoparticle preparation. Risedronate sodium (Biopharmaceutical Classification System Class III) was chosen as a model compound with high water solubility and low ...
Eliska Vaculikova +6 more
doaj +1 more source
Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development
Nature Communications, 2023 Chronic colonic inflammation is a feature of cancer and is strongly associated with tumorigenesis, but its underlying molecular mechanisms remain poorly understood.
Mingyu Lee +10 more
doaj +1 more source
Vimentin Suppresses Inflammation and Tumorigenesis in the Mouse Intestine
Frontiers in Cell and Developmental Biology, 2022 Vimentin has been implicated in wound healing, inflammation, and cancer, but its functional contribution to intestinal diseases is poorly understood.
Linglu Wang +16 more
doaj +1 more source
Oncology Reports, 2006 Pathogenic mechanisms responsible for inflammatory bowel disease (IBD) are poorly understood. In an IBD animal model, the oral administration of polysaccharides such as dextran sulfate sodium (DSS) induces colitis, which exhibit several clinical and histological features for IBD. However, pathogenic factors in the development of colitis remain unclear.
Yoshio, Araki +2 more
openaire +3 more sources
Dextran Sodium Sulfate-induced Colitis as a Model for Sarcopenia in Mice [PDF]
Inflammatory Bowel Diseases, 2019 Forty-two percent of inflammatory bowel disease patients suffer from sarcopenia. We established a mouse model for this condition. Dextran sodium sulfate–induced colitis caused a severe decrease in muscle mass, fiber size, and the regulation of sarcopenia-associated key players on mRNA level.
Dominik Saul, Robyn Laura Kosinsky
openaire +3 more sources
On the dynamics of nitrite, nitrate and other biomarkers of nitric oxide production in inflammatory bowel disease [PDF]
, 2010 Nitrite and nitrate are frequently used surrogate markers of nitric oxide (NO) production. Using rat models of acute and chronic DSS-induced colitis we examined the applicability of these and other NO-related metabolites, in tissues and blood, for the ...
Fumito Saijo +19 more
core +1 more source
The mouse CRC model was induced using the azoxymethane/dextran sulfate sodium salt method.
, 2023 The mouse CRC model was induced using the azoxymethane/dextran sulfate sodium salt method.
Jinhua Tian (5655472) +8 more
core +1 more source