Results 41 to 50 of about 102,443 (368)
Beilstein Journal of Organic Chemistry, 2015 Novel (S)-camptothecin–dextran polymers were obtained by “click” grafting of azide-modified (S)-camptothecin and alkyne-modified dextrans. Two series based on 10 kDa and 70 kDa dextrans were prepared with a degree of substitution of (S)-camptothecin ...
Thorbjørn Terndrup Nielsen +6 more
doaj +1 more source
Inducing an LCST in hydrophilic polysaccharides via engineered macromolecular hydrophobicity
Scientific Reports, 2023 Thermoresponsive polysaccharide-based materials with tunable transition temperatures regulating phase-separated microdomains offer substantial opportunities in tissue engineering and biomedical applications.
Saniya Yesmin Bubli +5 more
doaj +1 more source
Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability [PDF]
, 2016 Sizing nanomaterials in complex biological fluids, such as blood, remains a great challenge in spite of its importance for a wide range of biomedical applications. In drug delivery, for instance, it is essential that aggregation of protein-based drugs is
Braeckmans, Kevin +8 more
core +2 more sources
The Induction of Oxidative/Nitrosative Stress, Inflammation, and Apoptosis by a Ferric Carboxymaltose Copy Compared to Iron Sucrose in a Non-Clinical Model [PDF]
, 2015 Introduction: Ferric carboxymaltose is a next-generation polynuclear iron(III)-hydroxide carbohydrate complex for intravenous iron therapy belonging to the class of so-called non-biological complex drugs.
Angerosa, Margarita +2 more
core +1 more source
THE PERMEABILITY OF GLOMERULAR CAPILLARIES TO GRADED DEXTRANS
Journal of Cell Biology, 1974 Graded dextrans have been used as tracers to identify the primary permeability barrier(s) to macromolecules among the structural elements (endothelium, mesangium, basement membrane, epithelium) of the glomerular capillary wall.
J. Caulfield, M. Farquhar
semanticscholar +1 more source
eFoodAlthough ultraviolet (UV)/H2O2 treatment could effectively improve the bioactivities of polysaccharides, the relationship between free radical‐induced structural changes and the bioactivities of products remains unknown. Therefore, this work investigated
Biyang Zhu +4 more
doaj +1 more source
eLife, 2017 Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed ‘glymphatic’ clearance mechanism additionally suggests that ...
Alex J Smith +4 more
doaj +1 more source
Aqueous Angiography: Real-Time and Physiologic Aqueous Humor Outflow Imaging. [PDF]
PLoS ONE, 2016 PURPOSE:Trabecular meshwork (TM) bypass surgeries attempt to enhance aqueous humor outflow (AHO) to lower intraocular pressure (IOP). While TM bypass results are promising, inconsistent success is seen.
Sindhu Saraswathy +6 more
doaj +1 more source
Formation of Microcages from a Collagen Mimetic Peptide via Metal-Ligand Interactions
Molecules, 2021 Here, the hierarchical assembly of a collagen mimetic peptide (CMP) displaying four bipyridine moieties is described. The CMP was capable of forming triple helices followed by self-assembly into disks and domes.
Jeremy Gleaton +2 more
doaj +1 more source
VH-RELATED IDIOTOPES DETECTED BY SITE-DIRECTED MUTAGENESIS [PDF]
, 1992 The function of the CD4 cell surface protein as coreceptor on T helper lymphocytes and as receptor for HIV makes this glycoprotein a prime target for an immune intervention with mAb.
Cheng, Y. H. +4 more
core +1 more source