Results 41 to 50 of about 29,023 (291)
Investigation of the spatiotemporal responses of nanoparticles in tumor tissues with a small-scale mathematical model. [PDF]
PLoS ONE, 2013 The transport and accumulation of anticancer nanodrugs in tumor tissues are affected by many factors including particle properties, vascular density and leakiness, and interstitial diffusivity.
Cheng-Ying Chou +4 more
doaj +1 more source
Gels, 2022 Dextransucrases released by certain lactic acid bacteria form glucose polymers with predominantly α-1,6-linkages and may be exploited biotechnologically for the tailored production of polysaccharides with application potential.
Julia Bechtner +4 more
doaj +1 more source
Dextran and Insulin in Rats [PDF]
Nature, 1960 WHILE testing the effects of insulin on the circulatory reaction of laboratory rats to dextran, we found that many animals died after combined doses of the two agents which were not lethal when administered separately. The validity of this observation was put to experimental test. Male Sprague-Dawley rats weighing at least 150 gm.
C H Hanna, L. H. Marshall
openaire +3 more sources
Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski +9 more
wiley +1 more source
Advanced Functional Materials, EarlyView.The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang +9 more
wiley +1 more source
Effects of dextran and dextran sulfate on the glucoamylase-catalyzed reaction.
Agricultural and Biological Chemistry, 1977 The hydrolysis of maltose by glucoamylase (EC 3. 2. 1. 3 from Rhizopus niveus) was carried out in the presence and absence of dextran and dextran sulfate, which are the components of supports of immobilized enzymes. The interaction between dextran and the enzyme was observed by the fluorescence spectrophotometry.
Kazuhiro Nakanishi +3 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Th17 Cytokines Disrupt the Airway Mucosal Barrier in Chronic Rhinosinusitis
Mediators of Inflammation, 2016 Cytokine mediated changes in paracellular permeability contribute to a multitude of pathological conditions including chronic rhinosinusitis (CRS). The purpose of this study was to investigate the effect of interferons and of Th1, Th2, and Th17 cytokines
Mahnaz Ramezanpour +4 more
doaj +1 more source
Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy
Advanced Functional Materials, EarlyView.Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi +6 more
wiley +1 more source