Results 41 to 50 of about 18,497 (276)
eLife, 2017 Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed ‘glymphatic’ clearance mechanism additionally suggests that ...
Alex J Smith +4 more
doaj +1 more source
Aqueous Angiography: Real-Time and Physiologic Aqueous Humor Outflow Imaging. [PDF]
PLoS ONE, 2016 PURPOSE:Trabecular meshwork (TM) bypass surgeries attempt to enhance aqueous humor outflow (AHO) to lower intraocular pressure (IOP). While TM bypass results are promising, inconsistent success is seen.
Sindhu Saraswathy +6 more
doaj +1 more source
Uptake of macromolecules by cercariae during skin penetration and transformation to schistosomula (Schistosoma mansoni) [PDF]
, 2010 Here, we observed the uptake of membrane-impermeant molecules by cercariae as they penetrate the skin and are transformed into schistosomula. We propose that membrane-impermeant molecules, Lucifer Yellow, Propidium iodide and Hoechst 33258 enter the ...
Alvisi de Oliviera, Fabricia +7 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Large molecules from the cerebrospinal fluid enter the optic nerve but not the retina of mice
Fluids and Barriers of the CNSIt has been proposed that cerebrospinal fluid (CSF) can enter and leave the retina and optic nerve along perivascular spaces surrounding the central retinal vessels as part of an aquaporin-4 (AQP4) dependent ocular ‘glymphatic’ system.
Xiao J. Tong +4 more
doaj +1 more source
Biomaterials Research, 2020 Background Transdermal delivery is of great importance for the effective delivery of bioactive or therapeutic agents into a body. The microporation device based on radiofrequency can be used to enhance delivery efficiency by removing the epidermis layer.
Guk Young Ahn +3 more
doaj +1 more source
Calibration of ultrafiltration membranes against size exclusion chromatography columns [PDF]
, 2010 Using the extension of the concept of universal calibration parameter, yielding a relation between the hydrodynamic volume of molecules and the elution volume in sizeexclusionchromatography (SEC), to retention coefficients in ultrafiltration (UF), we ...
Aimar, Pierre, Meireles, Martine
core +2 more sources
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers
Scientific Reports, 2020 Enteric bacteria and/or their products are necessary for doxorubicin (DXR)-induced small intestine mucosal damage. While DXR does not induce gross loss of epithelium, others have shown elevated serum endotoxin after DXR administration.
Paul Cray +3 more
doaj +1 more source
The Induction of Oxidative/Nitrosative Stress, Inflammation, and Apoptosis by a Ferric Carboxymaltose Copy Compared to Iron Sucrose in a Non-Clinical Model [PDF]
, 2015 Introduction: Ferric carboxymaltose is a next-generation polynuclear iron(III)-hydroxide carbohydrate complex for intravenous iron therapy belonging to the class of so-called non-biological complex drugs.
Angerosa, Margarita +2 more
core +1 more source